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  • In vivo visualization of cardiac extracellular adenosine dynamics and its pharmacological modulation in zebrafish heart failure models


    Phurpa Phurpa, Magdeline E. Carrasco Apolinario, Ryohei Umeda, Shinichiro Kume, Hitoshi Teranishi, Nobuyuki Shimizu, Mengting Shan, Kenshiro Shikano, Tatsuki Kurokawa, Takatoshi Hikida, Toshikatsu Hanada, Yulong Li, and Reiko Hanada, “In vivo visualization of cardiac extracellular adenosine dynamics and its pharmacological modulation in zebrafish heart failure models,” Scientific Reports, vol. 16, Art. no. 8220, 2026.

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  • Experimental lung ultrasound scoring in a murine model of aspiration pneumonia: Challenges and diagnostic perspectives


    Ching-Wei Chuang, Wen-Yi Lai, Kuo-Wei Chang, Chao-Yuan Chang, Shang-Ru Yeoh, and Chun-Jen Huang, “Experimental lung ultrasound scoring in a murine model of aspiration pneumonia: Challenges and diagnostic perspectives,” Diagnostics, vol. 16, no. 2, Art. no. 361, 2026.

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  • Melatonin attenuates high-fat diet- and particulate matter-induced cardiac injury: Involvement of mitochondrial quality and miR-221/222 expression


    Ya-Chun Chen, Ming-Hsueh Lee, Szu-Ju Fu, Chiang-Wen Lee, Wen-Chi Shen, Tsai-Chun Lai, Shu-Rung Lin, Shu-Wha Lin, I-Shing Yu, Tzu-Yi Chuang, Jaw-Shiun Tsai, and Yuh-Lien Chen, “Melatonin attenuates high-fat diet- and particulate matter-induced cardiac injury: Involvement of mitochondrial quality and miR-221/222 expression,” Biochemical Pharmacology, vol. 242, Art. no. 117346, 2025.

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  • Transcranial ultrasound combined with intravenous metformin-loaded oxygenated microbubbles attenuates noise-induced hearing loss in mice


    Ai-Ho Liao, Chih-Hung Wang, Lin-Yi Chou, Yu-Chan Hung, Yi-Chun Lin, Ho-Chiao Chuang, Kuo-Hsing Ma, Hao-Li Liu, Jehng-Kang Wang, and Cheng-Ping Shih, “Transcranial ultrasound combined with intravenous metformin-loaded oxygenated microbubbles attenuates noise-induced hearing loss in mice,” Drug Delivery, vol. 32, no. 1, Art. no. 2576220, 2025.

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  • A zebrafish model of chronic heart failure caused by protein aggregation in heart valves


    Yitong Li, Shingo Maegawa, Ryo Kimura, Shiho R. Suzuki, Taiki Nishimura, and Masatoshi Hagiwara, “A zebrafish model of chronic heart failure caused by protein aggregation in heart valves,” Communications Biology, vol. 8, Art. no. 1520, 2025.

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  • MiR221/222 in the conditioned medium of adipose-derived stem cells attenuates particulate matter and high-fat diet-induced cardiac apoptosis


    Ya-Chun Chen, Chi-Ming Pu, Shu-Rung Lin, Shu-Wha Lin, I-Shing Yu, Ho-Jun Shih, Chiang-Wen Lee, Ming-Hsueh Lee, Yen-Ting Kuo, and Yuh-Lien Chen, “MiR221/222 in the conditioned medium of adipose-derived stem cells attenuates particulate matter and high-fat diet-induced cardiac apoptosis,” Stem Cell Research & Therapy, vol. 16, Art. no. 285, 2025.

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  • Deficiency of synaptotagmin-1 aggravates pressure overload-induced cardiac hypertrophy and dysfunction via the p38 MAPK signaling pathway in mice


    Jing Shen, Junqiu Miao, Lifei Wu, Deping Wang, Guang Li, Haixiong Wang, and Jimin Cao, “Deficiency of synaptotagmin-1 aggravates pressure overload-induced cardiac hypertrophy and dysfunction via the p38 MAPK signaling pathway in mice,” Human Cell, vol. 38, Art. no. 96, 2025.

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  • Subtherapeutic lithium supplementation causes physiological eccentric cardiac hypertrophy in young-adult wild-type male mice


    Sophie I. Hamstra, Mia S. Geromella, Peter Tiidus, Panagiota Klentrou, Rebecca E. K. MacPherson, and Val A. Fajardo, “Subtherapeutic lithium supplementation causes physiological eccentric cardiac hypertrophy in young-adult wild-type male mice,” Physiological Reports, vol. 13, no. 7, Art. no. e70299, 2025.

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  • Mir221- and Mir222-enriched adsc-exosomes mitigate PM exposure-exacerbated cardiac ischemia-reperfusion injury through the modulation of the BNIP3-MAP1LC3B-BBC3/PUMA pathway


    Tzu-Lin Lee, Wen-Chi Shen, Ya-Chun Chen, Tsai-Chun Lai, Shu-Rung Lin, Shu-Wha Lin, I-Shing Yu, Yen-Hsiu Yeh, Tsai-Kun Li, I-Ta Lee, Chiang-Wen Lee, and Yuh-Lien Chen, “Mir221- and Mir222-enriched adsc-exosomes mitigate PM exposure-exacerbated cardiac ischemia-reperfusion injury through the modulation of the BNIP3-MAP1LC3B-BBC3/PUMA pathway,” Autophagy, vol. 21, no. 2, pp. 374–393, 2025.

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  • Matrix mechanics regulates muscle regeneration by modulating kinesin-1 activity


    Wan-Yu Chiang, Helen Wenshin Yu, Ming-Chung Wu, Yi-Man Huang, Yin-Quan Chen, Jong-Wei Lin, Yen-Wenn Liu, Li-Ru You, Arthur Chiou, and Jean-Cheng Kuo, “Matrix mechanics regulates muscle regeneration by modulating kinesin-1 activity,” Biomaterials, vol. 308, Art. no. 122551, 2024.

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  • ENG is a biomarker of prognosis and angiogenesis in liver cancer, and promotes the differentiation of tumor cells into vascular ECs


    Shangheng Shi, Cunle Zhu, Yue Hu, Peng Jiang, Jinxin Zhao, and Qingguo Xu, “ENG is a biomarker of prognosis and angiogenesis in liver cancer, and promotes the differentiation of tumor cells into vascular ECs,” Frontiers in Bioscience-Landmark, vol. 29, no. 9, Art. no. 315, 2024.

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  • STING activation disrupts tumor vasculature to overcome the EPR limitation and increase drug deposition


    Xiaomin Jiang, Taokun Luo, Kaiting Yang, Morten J. Lee, Jing Liu, Langston Tillman, Wenyao Zhen, Ralph R. Weichselbaum, and Wenbin Lin, “STING activation disrupts tumor vasculature to overcome the EPR limitation and increase drug deposition,” Science Advances, vol. 10, Art. no. 29, 2024.

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  • Reflected shear wave computed tomography for elasticity imaging of 3D cell cultures using a single-element transducer


    Ting-Wei Chen, You-Chuan Chen, and Pai-Chi Li, “Reflected shear wave computed tomography for elasticity imaging of 3D cell cultures using a single-element transducer,” Applied Physics Letters, vol. 124, Art. no. 23, 2024.

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  • Iontophoresis-enhanced buccal delivery of cisplatin-encapsulated chitosan nanoparticles for treating oral cancer in a mouse model


    Yi-Wen Chen, Ai-Chia He, Tzu-Yun Huang, De-Hao Lai, Yi-Ping Wang, Wei-Wen Liu, Wei-Ting Kuo, Hsin-Han Hou, Shih-Jung Cheng, Chen-Yi Lee, Wei-Chun Chuang, Che-Chen Chang, and Bor-Shiunn Lee, “Iontophoresis-enhanced buccal delivery of cisplatin-encapsulated chitosan nanoparticles for treating oral cancer in a mouse model,” International Journal of Nanomedicine, vol. 19, pp. 10435–10453, 2024.

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  • Inhibition of G protein-coupled receptor 68 using homoharringtonine attenuates chronic kidney disease-associated cardiac impairment


    Yuya Yoshida, Kohei Fukuoka, Miyu Sakugawa, Masayuki Kurogi, Kengo Hamamura, Keika Hamasaki, Fumiaki Tsurusaki, Kurumi Sotono, Takumi Nishi, Taiki Fukuda, Taisei Kumamoto, Kosuke Oyama, Takashi Ogino, Akito Tsuruta, Kouta Mayanagi, Tomohiro Yamashita, Hiroyuki Fuchino, Nobuo Kawahara, Kayo Yoshimatsu, Hitomi Kawakami, Satoru Koyanagi, Naoya Matsunaga, and Shigehiro Ohdo, “Inhibition of G protein-coupled receptor 68 using homoharringtonine attenuates chronic kidney disease-associated cardiac impairment,” Translational Research, vol. 269, pp. 31–46, 2024.

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  • Treatment with a new barbituric acid derivative suppresses diet-induced metabolic dysfunction and non-alcoholic fatty liver disease in mice


    Fat-Moon Suk, Fang-Yu Hsu, Ming-Hua Hsu, Wan-Chun Chiu, Cheng-Chieh Fang, Tzu-Lang Chen, and Yi-Jen Liao, “Treatment with a new barbituric acid derivative suppresses diet-induced metabolic dysfunction and non-alcoholic fatty liver disease in mice,” Life Sciences, vol. 336, Art. no. 122327, 2024.

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  • Synaptotagmin-7 mediates cardiac hypertrophy by targeting autophagy


    Teng Sun, Yu Han, Jia-Lei Li, Shuang Wang, Zhi-Jie Jing, Zi Yan, Lan Zhou, Lin Zuo, Jun-Li Yang, and Ji-Min Cao, “Synaptotagmin-7 mediates cardiac hypertrophy by targeting autophagy,” FEBS Journal, vol. 291, pp. 489–509, 2024.

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  • Optimizing cell therapy by sorting cells with high extracellular vesicle secretion


    Doyeon Koo, Xiao Cheng, Shreya Udani, Dashuai Zhu, Junlang Li, Brian Hall, Natalie Tsubamoto, Shiqi Hu, Jina Ko, Ke Cheng, and Dino Di Carlo, “Optimizing cell therapy by sorting cells with high extracellular vesicle secretion,” Nature Communications, vol. 15, Art. no. 4870, 2024.

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  • A novel caffeic acid derivative prevents angiotensin II-induced cardiac remodeling


    Shih-Yi Lee, Yueh-Hsiung Kuo, Chen-Xuan Du, Cheng-Wei Huang, and Hui-Chun Ku, “A novel caffeic acid derivative prevents angiotensin II-induced cardiac remodeling,” Biomedicine & Pharmacotherapy, vol. 162, Art. no. 114709, 2023.

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  • VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid–liquid phase separation


    Yuma Horii, Shoichi Matsuda, Chikashi Toyota, Takumi Morinaga, Takeo Nakaya, Soken Tsuchiya, Masaki Ohmuraya, Takanori Hironaka, Ryo Yoshiki, Kotaro Kasai, Yuto Yamauchi, Noburo Takizawa, Akiomi Nagasaka, Akira Tanaka, Hidetaka Kosako, and Michio Nakaya, “VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid–liquid phase separation,” Nature Communications, vol. 14, Art. no. 550, 2023.

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  • Establishment of ultrasound-responsive SonoBacteriaBot for targeted drug delivery and controlled release


    Meng Du, Ting Wang, Renjie Feng, Penghui Zeng, and Zhiyi Chen, “Establishment of ultrasound-responsive SonoBacteriaBot for targeted drug delivery and controlled release,” Frontiers in Bioengineering and Biotechnology, vol. 11, Art. no. 1144963, 2023.

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  • Alleviating effects of ovatodiolide and antcin K supplements on high-fat diet-induced cardiovascular dysfunction in ApoE-knockout mice by attenuating oxidative stress


    Chen-Wen Lu, Wen-Jhen Wu, Thi Kim Ngan Nguyen, Szu-Chuan Shen, Yeh-B. Wu, Hui-Ju Liang, and Chung-Hsin Wu, “Alleviating effects of ovatodiolide and antcin K supplements on high-fat diet-induced cardiovascular dysfunction in ApoE-knockout mice by attenuating oxidative stress,” Nutrients, vol. 15, Art. no. 18, 2023.

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  • Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of lamin A toxicity


    Chia Yee Tan, Pui Shi Chan, Hansen Tan, Sung Wei Tan, Chang Jie Mick Lee, Jiong-Wei Wang, Shu Ye, Hendrikje Werner, Ying Jie Loh, Yin Loon Lee, Matthew Ackers-Johnson, Roger S. Y. Foo, and Jianming Jiang, “Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of lamin A toxicity,” Journal of Translational Medicine, vol. 21, Art. no. 690, 2023.

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  • A novel needle mouse model of vascular cognitive impairment and dementia


    Zhongfang Weng, Catherine Cao, Nadezda A. Stepicheva, Fenghua Chen, Lesley M. Foley, Sarah Cao, Mohammad Iqbal H. Bhuiyan, Qingde Wang, Yuan Wang, T. Kevin Hitchens, Dandan Sun, and Guodong Cao, “A novel needle mouse model of vascular cognitive impairment and dementia,” Journal of Neuroscience, vol. 43, no. 44, pp. 7351–7360, 2023.

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  • Pharmacological inhibition of gasdermin D suppresses angiotensin II-induced experimental abdominal aortic aneurysms


    Jia Guo, Jinyun Shi, Min Qin, Yan Wang, Zhidong Li, Takahiro Shoji, Toru Ikezoe, Yingbin Ge, and Baohui Xu, “Pharmacological inhibition of gasdermin D suppresses angiotensin II-induced experimental abdominal aortic aneurysms,” Biomolecules, vol. 13, no. 6, Art. no. 899, 2023.

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  • Overexpression of GRK2 in vascular smooth muscle leads to inappropriate hypertension and acute heart failure as in clinical scenario 1


    Hiroki Yano, Kenji Onoue, Shiho Tokinaga, Tomoko Ioka, Satomi Ishihara, Yukihiro Hashimoto, Yasuki Nakada, Hitoshi Nakagawa, Tomoya Ueda, Ayako Seno, Taku Nishida, Makoto Watanabe, and Yoshihiko Saito, “Overexpression of GRK2 in vascular smooth muscle leads to inappropriate hypertension and acute heart failure as in clinical scenario 1,” Scientific Reports, vol. 13, Art. no. 7707, 2023.

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  • Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair


    Dashuai Zhu, Shuo Liu, Ke Huang, Junlang Li, Xuan Mei, Zhenhua Li, and Ke Cheng, “Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair,” European Heart Journal, vol. 44, no. 19, pp. 1748–1760, 2023.

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  • Treatment efficacy of low-dose 5-fluorouracil with ultrasound in mediating 5-fluorouracil-loaded microbubble cavitation in head and neck cancer


    Ai-Ho Liao, Yu-An Lee, Dao-Lung Lin, Ho-Chiao Chuang, Jehng-Kang Wang, Ching-En Chang, Hsiang-Tzu Li, Ting-Yi Wu, Cheng-Ping Shih, Chih-Hung Wang, and Yueng-Hsiang Chu, “Treatment efficacy of low-dose 5-fluorouracil with ultrasound in mediating 5-fluorouracil-loaded microbubble cavitation in head and neck cancer,” Drug Delivery, vol. 30, no. 1, pp. 1–13, 2023.

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  • Cancer 'avatars': Patient-derived xenograft growth correlation with postoperative recurrence and survival in pancreaticobiliary cancer


    Isaac T. Lynch, Amro M. Abdelrahman, Roberto Alva-Ruiz, Alessandro Fogliati, Rondell P. Graham, Rory Smoot, and Mark J. Truty, “Cancer 'avatars': Patient-derived xenograft growth correlation with postoperative recurrence and survival in pancreaticobiliary cancer,” Journal of the American College of Surgeons, vol. 237, no. 3, pp. 483–500, 2023.

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  • Combined use of microbubbles of various sizes and single-transducer dual-frequency ultrasound for safe and efficient inner ear drug delivery


    Ai-Ho Liao, Chih-Hung Wang, Bo-Han Wang, Yi-Chun Lin, Ho-Chiao Chuang, Hao-Li Liu, and Cheng-Ping Shih, “Combined use of microbubbles of various sizes and single-transducer dual-frequency ultrasound for safe and efficient inner ear drug delivery,” Bioengineering and Translational Medicine, vol. 8, no. 5, Art. no. e10450, 2023.

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  • The imaging performance of preclinical ultrasound scanners using the Edinburgh pipe phantom


    Carmel M Moran, Christopher McLeod, Karne McBride, Scott Inglis, Adrian JW Thomson, and Stephen D Pye, “The imaging performance of preclinical ultrasound scanners using the Edinburgh pipe phantom,” Frontiers in Physics, vol. 10, Art. no. 802588, 2022.

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  • Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction


    Junlang Li, Yongbo Lv, Dashuai Zhu, Xuan Mei, Ke Huang, Xianyun Wang, Zhenhua Li, Sichen Zhang, Shiqi Hu, Kristen D. Popowski, Ke Cheng, and Juan Wang, “Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction,” Chemical Engineering Journal, vol. 427, Art. no. 131581, 2022.

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  • Ultrasound shear-wave computed tomography for elasticity imaging


    Geng-Shi Jeng, Chia-Lun Yeh, Chia-Lin Lee, Yung-Shao Yang, Ling-Yi Tseng, and Pai-Chi Li, “Ultrasound shear-wave computed tomography for elasticity imaging,” Applied Physics Letters, vol. 121, no. 4, Art. no. 043702, 2022.

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  • Allogeneic expanded human peripheral NK cells control prostate cancer growth in a preclinical mouse model of castration-resistant prostate cancer


    Fangming Wang, Xuejiao Dong, Jing Wang, Feiya Yang, Donghua Liu, Jianlin Ma, Shuai Liu, Dehua Chang, and Nianzeng Xing, “Allogeneic expanded human peripheral NK cells control prostate cancer growth in a preclinical mouse model of castration-resistant prostate cancer,” Journal of Immunology Research, vol. 2022, Art. no. 1786395, 2022.

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  • Longitudinal shear wave elasticity measurements of millimeter-sized biomaterials using a single-element transducer platform


    Shao-Lun Lu, Pei-Yu Chao, Wei-Wen Liu, Kun Han, Jason Chia-Hsien Cheng, and Pai-Chi Li, “Longitudinal shear wave elasticity measurements of millimeter-sized biomaterials using a single-element transducer platform,” PLOS ONE, vol. 17, no. 4, Art. no. e0266235, 2022.

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  • Global profiling of protein lysine malonylation in mouse cardiac hypertrophy


    Li-Fei Wu, De-Ping Wang, Jing Shen, Li-Juan Gao, Ying Zhou, Qing-Hua Liu, and Ji-Min Cao, “Global profiling of protein lysine malonylation in mouse cardiac hypertrophy,” Journal of Proteomics, vol. 266, Art. no. 104667, 2022.

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  • 5-methoxytryptophan attenuates postinfarct cardiac injury by controlling oxidative stress and immune activation


    Wan-Tseng Hsu, Ya-Hsuan Tseng, Hsiang-Yiang Jui, Chen-Chin Kuo, Kenneth K Wu, and Chii-Ming Lee, “5-methoxytryptophan attenuates postinfarct cardiac injury by controlling oxidative stress and immune activation,” Journal of Molecular and Cellular Cardiology, vol. 158, pp. 101–114, 2021.

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  • Stepwise candidate drug screening for myopia control by using zebrafish, mouse, and Golden Syrian hamster myopia models


    Meng-Yin Lin, I-Tsen Lin, Yu-Ching Wu, and I-Jong Wang, “Stepwise candidate drug screening for myopia control by using zebrafish, mouse, and Golden Syrian hamster myopia models,” EBioMedicine, vol. 65, Art. no. 103263, 2021.

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  • A novel ALDH2 activator AD-9308 improves diastolic and systolic myocardial functions in streptozotocin-induced diabetic mice


    Hsiao-Lin Lee, Siow-Wey Hee, Chin-Feng Hsuan, Wenjin Yang, Jing-Yong Huang, Ya-Ling Lin, Chih-Neng Hsu, Juey-Jen Hwang, Shiau-Mei Chen, Zhi-Zhong Ding, Tung-Yuan Lee, Yu-Chiao Lin, Feng-Chiao Tsai, Wei-Lun Su, Li-Yun Chueh, Meng-Lun Hsieh, Che-Hong Chen, Daria Mochly-Rosen, Yi-Cheng Chang, and Lee-Ming Chuang, “A novel ALDH2 activator AD-9308 improves diastolic and systolic myocardial functions in streptozotocin-induced diabetic mice,” Antioxidants, vol. 10, no. 3, Art. no. 450, 2021.

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  • A shift in tissue stiffness during hippocampal maturation correlates to the pattern of neurogenesis and composition of the extracellular matrix


    Youngjae Ryu, Misato Iwashita, Wonyoung Lee, Kenji Uchimura, and Yoichi Kosodo, “A shift in tissue stiffness during hippocampal maturation correlates to the pattern of neurogenesis and composition of the extracellular matrix,” Frontiers in Aging Neuroscience, vol. 13, Art. no. 709620, 2021.

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  • Development of thermosensitive poloxamer 407-based microbubble gel with ultrasound mediation for inner ear drug delivery


    Ai-Ho Liao, Cheng-Ping Shih, Ming-Wei Li, Yi-Chun Lin, Ho-Chiao Chuang, and Chih-Hung Wang, “Development of thermosensitive poloxamer 407-based microbubble gel with ultrasound mediation for inner ear drug delivery,” Drug Delivery, vol. 28, no. 1, pp. 1256–1271, 2021.

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  • Minoxidil-coated lysozyme-shelled microbubbes combined with ultrasound for the enhancement of hair follicle growth: Efficacy in vitro and in vivo


    Ai-Ho Liao, Yu-Jhen Huang, Ho-Chiao Chuang, Chih-Hung Wang, Cheng-Ping Shih, and Chien-Ping Chiang, “Minoxidil-coated lysozyme-shelled microbubbes combined with ultrasound for the enhancement of hair follicle growth: Efficacy in vitro and in vivo,” Frontiers in Pharmacology, vol. 12, Art. no. 668754, 2021.

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  • Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway


    Tzu-Lin Lee, Tsai-Chun Lai, Shu-Rung Lin, Shu-Wha Lin, Yu-Chen Chen, Chi-Ming Pu, I-Ta Lee, Jaw-Shiun Tsai, Chiang-Wen Lee, and Yuh-Lien Chen, “Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway,” Theranostics, vol. 11, no. 7, pp. 3131–3149, 2021.

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  • Evaluation of antitumor immunity by a combination treatment of high-dose irradiation, anti-PDL1, and anti-angiogenic therapy in murine lung tumors


    Jenny Ling-Yu Chen, ChunKai Pan, Yu-Sen Huang, Ching-Yi Tsai, Chun-Wei Wang, Yu-Li Lin, Sung-Hsin Kuo, and Ming-Jium Shieh, “Evaluation of antitumor immunity by a combination treatment of high-dose irradiation, anti-PDL1, and anti-angiogenic therapy in murine lung tumors,” Cancer Immunology, Immunotherapy, vol. 70, no. 2, pp. 391–404, 2021.

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  • MicroRNA-221/222 mediates ADSC-exosome-induced cardioprotection against ischemia/reperfusion by targeting PUMA and ETS-1


    Tsai-Chun Lai, Tzu-Lin Lee, Yu-Chun Chang, Yu-Chen Chen, Shu-Rung Lin, Shu-Wha Lin, Chi-Ming Pu, Jaw-Shiun Tsai, and Yuh-Lien Chen, “MicroRNA-221/222 mediates ADSC-exosome-induced cardioprotection against ischemia/reperfusion by targeting PUMA and ETS-1,” Frontiers in Cell and Developmental Biology, vol. 8, Art. no. 569150, 2020.

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  • Bispecific antibody inhalation therapy for redirecting stem cells from the lungs to repair heart injury


    Mengrui Liu, Halle Lutz, Dashuai Zhu, Ke Huang, Zhenhua Li, Phuong‐Uyen C Dinh, Junqing Gao, Yi Zhang, and Ke Cheng, “Bispecific antibody inhalation therapy for redirecting stem cells from the lungs to repair heart injury,” Advanced Science, vol. 8, no. 1, Art. no. 2002127, 2020.

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  • Heparanase from triple-negative breast cancer and platelets acts as an enhancer of metastasis


    Wen-Jing Yang, Gan-Lin Zhang, Ke-Xin Cao, Xiao-Ni Liu, Xiao-Min Wang, MingWei Yu, JinPing Li, and Guo-Wang Yang, “Heparanase from triple-negative breast cancer and platelets acts as an enhancer of metastasis,” International Journal of Oncology, vol. 57, no. 4, pp. 890–904, 2020.

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  • Enhanced radiosensitization for cancer treatment with gold nanoparticles through sonoporation


    Shao-Lun Lu, Wei-Wen Liu, Jason Chia-Hsien Cheng, Lien-Chieh Lin, Churng-Ren Chris Wang, and Pai-Chi Li, “Enhanced radiosensitization for cancer treatment with gold nanoparticles through sonoporation,” International Journal of Molecular Sciences, vol. 21, Art. no. 8370, 2020.

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  • miR‐26a attenuates cardiac apoptosis and fibrosis by targeting ataxia–telangiectasia mutated in myocardial infarction


    Ming‐Hsien Chiang, Chan‐Jung Liang, Lung‐Chun Lin, Yi‐Fan Yang, Ching‐Chang Huang, Ying‐Hsien Chen, Hsien‐Li Kao, Yu‐Chen Chen, Shin‐Rong Ke, Chiang‐Wen Lee, Mao‐Shin Lin, and Yuh‐Lien Chen, “miR‐26a attenuates cardiac apoptosis and fibrosis by targeting ataxia–telangiectasia mutated in myocardial infarction,” Journal of Cellular Physiology, vol. 235, no. 9, pp. 6085–6102, 2020.

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  • NIR dye-loaded mesoporous silica nanoparticles for a multifunctional theranostic platform: Visualization of tumor and ischemic lesions, and performance of photothermal therapy


    Sang Bong Lee, Ho Won Lee, Bobby Aditya Darmawan, In-Kyu Lee, Sung Jin Cho, Jungwook Chin, Sang Kyoon Kim, Jong-Oh Park, Kil Soo Kim, Sang-Woo Lee, Jaetae Lee, and Yong Hyun Jeon, “NIR dye-loaded mesoporous silica nanoparticles for a multifunctional theranostic platform: Visualization of tumor and ischemic lesions, and performance of photothermal therapy,” Journal of Industrial and Engineering Chemistry, vol. 88, pp. 99–105, 2020.

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  • Low-frequency dual-frequency ultrasound-mediated microbubble cavitation for transdermal minoxidil delivery and hair growth enhancement


    Ai-Ho Liao, Keng-Hsien Lin, Ho-Chiao Chuang, Chih-Hung Tsai, Yi-Chun Lin, Chih-Hung Wang, Cheng-Ping Shih, and Hao-Li Liu, “Low-frequency dual-frequency ultrasound-mediated microbubble cavitation for transdermal minoxidil delivery and hair growth enhancement,” Scientific Reports, vol. 10, Art. no. 4338, 2020.

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  • The potential effect of fucoidan on inhibiting epithelial-to-mesenchymal transition, proliferation, and increase in apoptosis for endometriosis treatment: In vivo and in vitro study


    Li-Chun Chang, Yi-Fen Chiang, Hsin-Yuan Chen, Yun-Ju Huang, An-Chieh Liu, and Shih-Min Hsia, “The potential effect of fucoidan on inhibiting epithelial-to-mesenchymal transition, proliferation, and increase in apoptosis for endometriosis treatment: In vivo and in vitro study,” Biomedicines, vol. 8, no. 11, Art. no. 528, 2020.

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  • Multimodal imaging techniques show differences in homing capacity between mesenchymal stromal cells and macrophages in mouse renal injury models


    Arthur Taylor, Jack Sharkey, Rachel Harwood, Lauren Scarfe, Michael Barrow, Matthew J. Rosseinsky, Dave J. Adams, Bettina Wilm, and Patricia Murray, “Multimodal imaging techniques show differences in homing capacity between mesenchymal stromal cells and macrophages in mouse renal injury models,” Molecular Imaging and Biology, vol. 22, no. 4, pp. 904–913, 2019.

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  • Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics


    Wei-Ting Ho, Jung-Shen Chang, San-Fang Chou, Wei-Lun Hwang, Po-Jen Shih, Shu-Wen Chang, Muh-Hwa Yang, Tzuu-Shuh Jou, and I-Jong Wang, “Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics,” Journal of Molecular Medicine, vol. 97, no. 9, pp. 1345–1357, 2019.

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  • A noninvasive imaging toolbox indicates limited therapeutic potential of conditionally activated macrophages in a mouse model of multiple organ dysfunction


    Jack Sharkey, Lorenzo Ressel, Nathalie Brillant, Lauren Scarfe, Bettina Wilm, B. Kevin Park, and Patricia Murray, “A noninvasive imaging toolbox indicates limited therapeutic potential of conditionally activated macrophages in a mouse model of multiple organ dysfunction,” Stem Cells International, vol. 2019, Art. no. 7386954, 2019.

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  • MiR-195-5p promotes cardiomyocyte hypertrophy by targeting MFN2 and FBXW7


    Lei Wang, Dongze Qin, Hongtao Shi, Yanan Zhang, Hao Li, and Qinghua Han, “MiR-195-5p promotes cardiomyocyte hypertrophy by targeting MFN2 and FBXW7,” BioMed Research International, vol. 2019, Art. no. 1580982, 2019.

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  • In vivo fate of free and encapsulated iron oxide nanoparticles after injection of labelled stem cells


    Sumaira Ashraf, Arthur Taylor, Jack Sharkey, Michael Barrow, Patricia Murray, Bettina Wilm, Harish Poptani, Matthew J. Rosseinsky, Dave J. Adams, and Raphaël Lévy, “In vivo fate of free and encapsulated iron oxide nanoparticles after injection of labelled stem cells,” Nanoscale Advances, vol. 1, no. 1, pp. 367–377, 2019.

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  • Ursolic acid prevents doxorubicin‐induced cardiac toxicity in mice through eNOS activation and inhibition of eNOS uncoupling


    Haiman Mu, Haiwen Liu, Jiayi Zhang, Jianhua Huang, Chen Zhu, Yue Lu, Yueping Shi, and Yi Wang, “Ursolic acid prevents doxorubicin‐induced cardiac toxicity in mice through eNOS activation and inhibition of eNOS uncoupling,” Journal of Cellular and Molecular Medicine, vol. 23, pp. 2174–2183, 2019.

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  • Echographic and physical characterization of albumin-stabilized nanobubbles


    Akiko Watanabe, Hong Sheng, Hitomi Endo, Loreto B. Feril, Yutaka Irie, Koichi Ogawa, Seyedeh Moosavi-Nejad, and Katsuro Tachibana, “Echographic and physical characterization of albumin-stabilized nanobubbles,” Heliyon, vol. 5, no. 6, Art. no. e01907, 2019.

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  • Functionalized holmium-doped hollow silica nanospheres for combined sonodynamic and hypoxia-activated therapy


    Yanke Wang, Yan Liu, Huixia Wu, Jianping Zhang, Qiwei Tian, and Shiping Yang, “Functionalized holmium-doped hollow silica nanospheres for combined sonodynamic and hypoxia-activated therapy,” Advanced Functional Materials, vol. 29, no. 3, Art. no. 1805764, 2019.

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  • Development of a PD-L1-expressing orthotopic liver cancer model: Implications for immunotherapy for hepatocellular carcinoma


    Da-Liang Ou, Yu-Yang Lin, Chia-Lang Hsu, Yin-Yao Lin, Chia-Wei Chen, Jhang-Sian Yu, Shi-Chuen Miaw, Ping-Ning Hsu, Ann-Lii Cheng, and Chiun Hsu, “Development of a PD-L1-expressing orthotopic liver cancer model: Implications for immunotherapy for hepatocellular carcinoma,” Liver Cancer, vol. 8, no. 3, pp. 155–171, 2019.

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  • Insulin-like growth factor binding protein related protein 1 knockdown attenuates hepatic fibrosis via the regulation of MMPs/TIMPs in mice


    Ren Jun-Jiea, Huang Ting-Juana, Zhang Qian-Qiana, Zhang Hai-Yana, Guo Xiao-Hong, Fan Hui-Qin, Li Ren-Ke, and Liu Li-Xin, “Insulin-like growth factor binding protein related protein 1 knockdown attenuates hepatic fibrosis via the regulation of MMPs/TIMPs in mice,” Hepatobiliary & Pancreatic Diseases International, vol. 18, no. 1, pp. 38–47, 2019.

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  • Real-time observation of pathophysiological processes during murine experimental schistosoma japonicum infection using high-resolution ultrasound imaging


    Katsumi Maezawa, Rieko Furushima-Shimogawara, Akio Yasukawa, Nobuo Ohta, and Shiro Iwanaga, “Real-time observation of pathophysiological processes during murine experimental schistosoma japonicum infection using high-resolution ultrasound imaging,” Tropical Medicine and Health, vol. 46, Art. no. 1, 2018.

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  • Ultrasound-mediated EGF-coated-microbubble cavitation in dressings for wound-healing applications


    Ai-Ho Liao, Chi-Ray Hung, Hang-Kang Chen, and Chien-Ping Chiang, “Ultrasound-mediated EGF-coated-microbubble cavitation in dressings for wound-healing applications,” Scientific Reports, vol. 8, Art. no. 8327, 2018.

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  • Surface-engineered nanobubbles with pH-/light-responsive drug release and charge-switchable behaviors for active NIR/MR/US imaging-guided tumor therapy


    Tianliang Li, Jia Zhou, Chunlei Zhang, Xiao Zhi, Jiaqi Niu, Hualin Fu, Jie Song, and Daxiang Cui, “Surface-engineered nanobubbles with pH-/light-responsive drug release and charge-switchable behaviors for active NIR/MR/US imaging-guided tumor therapy,” NPG Asia Materials, vol. 10, pp. 1046–1060, 2018.

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  • Ultrasound molecular imaging of breast cancer in MCF-7 orthotopic mice using gold nanoshelled poly(lactic-co-glycolic acid) nanocapsules: A novel dual-targeted ultrasound contrast agent


    Li Xu, Jing Du, Caifeng Wan, Yu Zhang, Shaowei Xie, Hongli Li, Hong Yang, and Fenghua Li, “Ultrasound molecular imaging of breast cancer in MCF-7 orthotopic mice using gold nanoshelled poly(lactic-co-glycolic acid) nanocapsules: A novel dual-targeted ultrasound contrast agent,” International Journal of Nanomedicine, vol. 13, pp. 1791–1807, 2018.

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  • Cardioprotective and functional effects of levosimendan and milrinone in mice with cecal ligation and puncture-induced sepsis


    Shigeyuki Yamashita, Tokiko Suzuki, Keisuke Iguchi, Takuya Sakamoto, Kengo Tomita, Hiroki Yokoo, Mari Sakai, Hiroki Misawa, Kohshi Hattori, Toshi Nagata, Yasuhide Watanabe, Naoyuki Matsuda, Naoki Yoshimura, and Yuichi Hattori, “Cardioprotective and functional effects of levosimendan and milrinone in mice with cecal ligation and puncture-induced sepsis,” Naunyn-Schmiedeberg's Archives of Pharmacology, vol. 391, no. 9, pp. 1021–1032, 2018.

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  • Exploration of antigen induced CaCO3 nanoparticles for therapeutic vaccine


    Shuang Wang, Dezhi Ni, Hua Yue, Nana Luo, Xiaobo Xi, Yugang Wang, Min Shi, Wei Wei, and Guanghui Ma, “Exploration of antigen induced CaCO3 nanoparticles for therapeutic vaccine,” Small, vol. 14, no. 14, Art. no. 1704272, 2018.

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  • Preparation and imaging investigation of dual-targeted C3F8-filled PLGA nanobubbles as a novel ultrasound contrast agent for breast cancer


    Jing Du, Xiao-Yu Li, He Hu, Li Xu, Shi-Ping Yang, and Feng-Hua Li, “Preparation and imaging investigation of dual-targeted C3F8-filled PLGA nanobubbles as a novel ultrasound contrast agent for breast cancer,” Scientific Reports, vol. 8, Art. no. 3887, 2018.

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  • SNR improvement and range side lobe suppression in golay-encoded Doppler detection for ultrasound high-frequency swept-scan imaging system


    Jyun-Gong Yu, Pin-Hsian Liu, and Che-Chou Shen, “SNR improvement and range side lobe suppression in golay-encoded Doppler detection for ultrasound high-frequency swept-scan imaging system,” Biomedical Signal Processing and Control, vol. 41, pp. 31–39, 2018.

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  • Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genes


    Joan Comenge, Jack Sharkey, Oihane Fragueiro, Bettina Wilm, Mathias Brust, Patricia Murray, Raphael Levy, and Antonius Plagge, “Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genes,” eLife, vol. 7, Art. no. e33140, 2018.

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  • Oral administration of ginsenoside Rg1 prevents cardiac toxicity induced by doxorubicin in mice through anti-apoptosis


    Chen Zhu, Yi Wang, Hua Liu, Haiman Mu, Yue Lu, Jiayi Zhang, and Jianhua Huang, “Oral administration of ginsenoside Rg1 prevents cardiac toxicity induced by doxorubicin in mice through anti-apoptosis,” Oncotarget, vol. 8, no. 48, pp. 83792–83801, 2017.

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  • Aliskiren improves ischemia- and oxygen glucose deprivation-induced cardiac injury through activation of autophagy and AMP-activated protein kinase


    Ming-Hsien Chiang, Chan-Jung Liang, Chen-Wei Liu, Bo-Jhih Pan, Wen-Ping Chen, Yi-Fan Yang, I-Ta Lee, Jaw-Shiun Tsai, Chiang-Wen Lee, and Yuh-Lien Chen, “Aliskiren improves ischemia- and oxygen glucose deprivation-induced cardiac injury through activation of autophagy and AMP-activated protein kinase,” Frontiers in Pharmacology, vol. 8, Art. no. 819, 2017.

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  • Exosomes derived from natural killer cells exert therapeutic effect in melanoma


    Liya Zhu, Senthilkumar Kalimuthu, Prakash Gangadaran, Ji-Min Oh, Ho-Won Lee, Se-Hwan Baek, Shin-Young Jeong, Sang-Woo Lee, Jaetae Lee, and Byeong-Cheol Ahn, “Exosomes derived from natural killer cells exert therapeutic effect in melanoma,” Theranostics, vol. 7, no. 10, pp. 2732–2745, 2017.

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  • Synergistic inhibitory effects on hepatocellular carcinoma with recombinant human adenovirus Aspp2 and oxaliplatin via p53-independent pathway in vitro and in vivo


    Xiaoni Liu, Jianji Xu, Shuang Wang, Xiaoxiao Yu, Boxin Kou, Mengyin Chai, Yunjin Zang, and Dexi Chen, “Synergistic inhibitory effects on hepatocellular carcinoma with recombinant human adenovirus Aspp2 and oxaliplatin via p53-independent pathway in vitro and in vivo,” International Journal of Oncology, vol. 51, no. 4, pp. 1291–1299, 2017.

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  • Diminished responsiveness to dobutamine as an inotrope in mice with cecal ligation and puncture-induced sepsis: Attribution to phosphodiesterase 4 upregulation


    Sakai M, Suzuki T, Tomita K, Yamashita S, Palikhe S, Hattori K, Yoshimura N, Matsuda N, and Hattori Y., “Diminished responsiveness to dobutamine as an inotrope in mice with cecal ligation and puncture-induced sepsis: Attribution to phosphodiesterase 4 upregulation,” American Journal of Physiology-Heart and Circulatory Physiology, vol. 312, no. 6, pp. H1224–H1237, 2017.

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  • Shear-wave elasticity measurements of three-dimensional cell cultures for mechanobiology


    Po-Ling Kuo, Chin-Che Charng, Po-Chen Wu, and Pai-Chi Li, “Shear-wave elasticity measurements of three-dimensional cell cultures for mechanobiology,” Journal of Cell Science, vol. 130, no. 1, pp. 292–302, 2017.

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  • Using high-frequency ultrasound statistical scattering model to assess nonalcoholic fatty liver disease (NAFLD) in mice


    Che-Chou Shen, Sheng-Chang Yu, and Chia-Yuan Liu, “Using high-frequency ultrasound statistical scattering model to assess nonalcoholic fatty liver disease (NAFLD) in mice,” presented at the Telecommunications and Signal Processing (TSP), Vienna, Austria, 2016.

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  • Evaluation of the enhancements with ultrasound-mediated retinoid loaded microbubbles on photoaging


    Ai-Ho Liao and You-Lin Cia, “Evaluation of the enhancements with ultrasound-mediated retinoid loaded microbubbles on photoaging,” presented at the WMIC 2016, New York, New York, USA, 2016.

  • Evaluation of the wound healing enhancements with ultrasound-mediated epidermal growth factor loaded lysozyme shelled microbubbles


    Ai-Ho Liao and Chi-Ruei Hong, “Evaluation of the wound healing enhancements with ultrasound-mediated epidermal growth factor loaded lysozyme shelled microbubbles,” presented at the WMIC 2016, New York, New York, USA, 2016.

  • Shear-wave measurements for evaluation of tendon diseases


    Chia-Lun Yeh, Po-Ling Kuo, Jean-Luc Gennisson, Javier Brum, Mickaël Tanter, and Pai-Chi Li, “Shear-wave measurements for evaluation of tendon diseases,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 63, no. 11, pp. 1906–1921, 2016.

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  • Efficacy of transdermal magnesium ascorbyl phosphate delivery after ultrasound treatment with microbubbles in gel-type surrounding medium in mice


    Ai-Ho Liao, Ying-Jui Lu, Chi-Ray Hung, and Meng-Yu Yang, “Efficacy of transdermal magnesium ascorbyl phosphate delivery after ultrasound treatment with microbubbles in gel-type surrounding medium in mice,” Materials Science and Engineering: C, vol. 61, no. 1, pp. 591–598, 2016.

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  • Nanodroplet-vaporization-assisted sonoporation for highly effective delivery of photothermal treatment


    Wei-Wen Liu, Shu-Wei Liu, Yu-Ren Liou, Yu-Hsun Wu, Ya-Chuen Yang, Churng-Ren Chris Wang, and Pai-Chi Li, “Nanodroplet-vaporization-assisted sonoporation for highly effective delivery of photothermal treatment,” Scientific Reports, vol. 6, no. 1, Art. no. 24753, 2016.

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  • Efficacy of combined ultrasound-and-microbubbles-mediated diclofenac gel delivery to enhance transdermal permeation in adjuvant-induced rheumatoid arthritis in the rat


    Ai-Ho Liao, Huan-Yu Chung, Wen-Shiang Chen, and Ming-Kung Yeh, “Efficacy of combined ultrasound-and-microbubbles-mediated diclofenac gel delivery to enhance transdermal permeation in adjuvant-induced rheumatoid arthritis in the rat,” Ultrasound in Medicine and Biology, vol. 42, no. 8, pp. 1976–1985, 2016.

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  • Acoustic and optical droplet vaporization for enhanced sonoporation


    Wei-Wen Liu, Chi-Ting Wu, Churng-Ren Chris Wang, and Pai-Chi Li, “Acoustic and optical droplet vaporization for enhanced sonoporation,” presented at the IEEE International Ultrasonics Symposium (IUS), Tours, France, Sept. 18–21, 2016.

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  • Preparation of pH-responsive hollow poly (MAA-co-EGDMA) nanocapsules for drug delivery and ultrasound imaging


    He Hu, Xiaofen Zhang, Jin Sun, Lu An, Jing Du, Hong Yang, Fenghua Li, Huixia Wua, and Shiping Yang, “Preparation of pH-responsive hollow poly (MAA-co-EGDMA) nanocapsules for drug delivery and ultrasound imaging,” RSC Advances, vol. 6, no. 105, pp. 103754–103762, 2016.

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  • Anti-inflammatory profile of levosimendan in cecal ligation-induced septic mice and in lipopolysaccharide-stimulated macrophages


    Qiang Wang, Hiroki Yokoo, Michinori Takashina, Kimimasa Sakata, Wakana Ohashi, Lobna A. Abedelzaher, Takahiro Imaizumi, Takuya Sakamoto, Kohshi Hattori, Naoyuki Matsuda, and Yuichi Hattori, “Anti-inflammatory profile of levosimendan in cecal ligation-induced septic mice and in lipopolysaccharide-stimulated macrophages,” Critical Care Medicine, vol. 43, no. 11, pp. e508-e520, 2015.

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  • Efficacy of ultrasound mediated microbubbles in diclofenac gel to enhance transdermal permeation in rheumatoid arthritis induced rat


    Ai-Ho Liao, Ho-Chiao Chuang, and Huan-Yu Chung, “Efficacy of ultrasound mediated microbubbles in diclofenac gel to enhance transdermal permeation in rheumatoid arthritis induced rat,” presented at the IEEE Engineering in Medicine and Biology Society (EMBC), Milan, Italy, Aug. 25–29, 2015.

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  • Evaluation the potential of the hair growth enhancements with ultrasound-mediated minoxidil loaded microbubbles cavitation


    Ai-Ho Liao, and Ying-Jui Lu, “Evaluation the potential of the hair growth enhancements with ultrasound-mediated minoxidil loaded microbubbles cavitation,” presented at the IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, Oct. 21–24, 2015.

  • Near field shear wave elasticity imaging with high frequency single element transducers


    Nien-Ching Ho and Pai-Chi Li, “Near field shear wave elasticity imaging with high frequency single element transducers,” presented at the IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, Oct. 21–24, 2015.

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  • Implementation and evaluation of slow-time golay decoding for pre-clinical high-frequency color Doppler imaging in mice


    Che-Chou Shen, Jyun-Gong Yu, and Gency Jeng, “Implementation and evaluation of slow-time golay decoding for pre-clinical high-frequency color Doppler imaging in mice,” presented at the IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, Oct. 21–24, 2015.

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  • Evaluating elasticity dynamics of three-dimensional cell-matrix using ultrasonic shear waves


    Po-Ling Kuo, and Pai-Chi Li, “Evaluating elasticity dynamics of three-dimensional cell-matrix using ultrasonic shear waves,” presented at the 8th AP Biomechanics, Sept. 16–19, 2015.

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  • Feasibility study of the hair growth enhancements with ultrasound-mediated minoxidil loaded microbubbles cavitation


    Ai-Ho Liao, and Ying-Jui Lu, “Feasibility study of the hair growth enhancements with ultrasound-mediated minoxidil loaded microbubbles cavitation,” presented at the WMIC 2015, Honolulu Hawaii, USA, Sept. 2–5, 2015.

  • The effect of moderate endurance exercise during doxorubicin-treatment in tumor-bearing mice


    Tai-Yuan Chuang, Brock T. Jensen, Mei-Li Chen, Hu Cheng, and Chia-Ying Lien, “The effect of moderate endurance exercise during doxorubicin-treatment in tumor-bearing mice,” presented at the WMIC 2015, Honolulu Hawaii, USA, Sept. 2–5, 2015.

  • DNase1 decrease the formation of the size of vegetation in experimental endocarditis rat model


    Jeng-Wei Chen, Ling-Yi Tseng, and Jean-San Chia, “DNase1 decrease the formation of the size of vegetation in experimental endocarditis rat model,” presented at the WMIC 2015, Honolulu Hawaii, USA, Sept. 2–5, 2015.

  • TGFβRI inhibition produces dual cardioprotective actions through increasing survivin and inhibiting Wnt expressions in cardiac progenitors


    Yu-Sian Ho, Fen-Chiung Lin, Wan-Hsuan Tsai, and Wen-Pin Chen, “TGFβRI inhibition produces dual cardioprotective actions through increasing survivin and inhibiting Wnt expressions in cardiac progenitors,” presented at the WMIC 2015, Honolulu Hawaii, USA, Sept. 2–5, 2015.

  • Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis


    Chia-Ying Lien, Tai-Yuan Chuang, Chih-Hsiang Hsu, Ching-Lung Lin, Sheue-Er Wang, Shuenn-Jyi Sheu, Chiang-Ting Chien, and Chung-Hsin Wu, “Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis,” OncoTargets and Therapy, vol. 8, pp. 1193–1210, 2015.

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  • Cardiac fibroblasts: Contributory role in septic cardiac dysfunction


    Kengo Tomita, Mitchinori Takashina, Natsumi Mizuno, Kimimasa Sakata, Kohshi Hattori, Joji Imura, Wakana Ohashi, and Yuichi Hattori, “Cardiac fibroblasts: Contributory role in septic cardiac dysfunction,” Journal of Surgical Research, vol. 193, no. 2, pp. 874–887, 2015.

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  • Evans blue extravasation in mouse tumor model using ultrasound image-guided sonoporation


    Ling-Yi Tseng, Yu-Ren Liou, Chung-Hsin Wang, Da-Liang Ou, and Pai-Chi Li, “Evans blue extravasation in mouse tumor model using ultrasound image-guided sonoporation,” presented at the WMIC 2014, Seoul, Korea, Sept. 17–20, 2014.

  • Combined therapeutic ultrasound with the microbubbles to enhance anti-inflammatory drug delivery in arthritis rat


    Huan-Yu Zhung, Ming-Kung Yeh, and Ai-Ho Liao, “Combined therapeutic ultrasound with the microbubbles to enhance anti-inflammatory drug delivery in arthritis rat,” presented at the WMIC 2014, Seoul, Korea, Sept. 17–20, 2014.

  • Assessment of whole body fat composition in mice using 3D local fat pad ultrasound imaging


    Ai-Ho Liao, Chun-Chieh Li, and Ho-Chiao Chuang, “Assessment of whole body fat composition in mice using 3D local fat pad ultrasound imaging,” presented at the WMIC 2014, Seoul, Korea, Sept. 17–20, 2014.

  • The effect of medical herbs (danshen and Panax ginseng) combination on doxorubicin-induced cardiotoxicity


    Tai-Yuan Chuang, Brock T. Jensen, Mei-Li Chen, Wu Chung-Hsin, and Chia-Ying Lien, “The effect of medical herbs (danshen and Panax ginseng) combination on doxorubicin-induced cardiotoxicity,” presented at the WMIC 2014, Seoul, Korea, Sept. 17–20, 2014.

  • Declined cardiac function causes aerobic exercise impairment in the R6/2 mice of Huntington’s disease


    Tai-Yuan Chuang, Chia-Ying Lien, Mei-Li Chen, Brock T. Jensen, Ding-Siang Huang, Sheue-Er Wang, Chih-hsiang Hsu, Chuang Hsing Huang, and Wu Chung-Hsin, “Declined cardiac function causes aerobic exercise impairment in the R6/2 mice of Huntington’s disease,” presented at the WMIC 2014, Seoul, Korea, Sept. 17–20, 2014.

  • Shear wave elastography of a liver fibrosis mouse model using a high frequency ultrasound system with mechanical scanning


    Chia-Lun Yeh, Bo-Rong Chen, Ling-Yi Tseng, Ping Jao, Tung-Hung Su, and Pai-Chi Li, “Shear wave elastography of a liver fibrosis mouse model using a high frequency ultrasound system with mechanical scanning,” presented at the IEEE International Ultrasonics Symposium (IUS), Chicago Illinois, USA, Sept. 3–6, 2014.

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  • 3D cell mechanobiology study using shear wave elasticity imaging


    Chun-Ting Li, Chin-Hsiung Tsai, Pai-Chi Li, and Po-Ling Kuo, “3D cell mechanobiology study using shear wave elasticity imaging,” presented at the IEEE International Ultrasonics Symposium (IUS), Chicago Illinois, USA, Sept. 3–6, 2014.

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  • Synergistic delivery of gold nanorods using multifunctional microbubbles for enhanced plasmonic photothermal therapy


    Yu-Hsin Wang, Shi-Ping Chen, Ai-Ho Liao, Ya-Chuen Yang, Cheng-Ru Lee, Cheng-Han Wu, Pei-Chun Wu, Tzu-Ming Liu, Churng-Ren Chris Wang, and Pai-Chi Li, “Synergistic delivery of gold nanorods using multifunctional microbubbles for enhanced plasmonic photothermal therapy,” Scientific Reports, vol. 4, Art. no. 5685, 2014.

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  • Prostate stem cell antigen antibody-conjugated multiwalled carbon nanotubes for targeted ultrasound imaging and drug delivery


    Huixia Wu, Haili Shi, Hao Zhang, Xue Wang, Yan Yang, Chao Yu, Caiqin Hao, Jing Du, He Hu, and Shiping Yang, “Prostate stem cell antigen antibody-conjugated multiwalled carbon nanotubes for targeted ultrasound imaging and drug delivery,” Biomaterials, vol. 35, no. 20, pp. 5369–5380, 2014.

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  • Paramagnetic hollow silica nanospheres for in vivo targeted ultrasound and magnetic resonance imaging


    Lu An, He Hu, Jing Du, Jie Wei, Li Wang, Hong Yang, Dongmei Wu, Haili Shi, Fenghua Li, and Shiping Yang, “Paramagnetic hollow silica nanospheres for in vivo targeted ultrasound and magnetic resonance imaging,” Biomaterials, vol. 35, no. 20, pp. 5381–5392, 2014.

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  • Non-invasive tissue elastography for measurement of liver fibrosis in mice, a pilot study


    Tung-Hung Su, Nien-Ching Ho, Ping Jao, Ling-Yi Tseng, Jia-Horng Kao, Pei-Jer Chen, Kuen-Feng Chen, Pai-Chi Li, and Shiou-Hwei Yeh, “Non-invasive tissue elastography for measurement of liver fibrosis in mice, a pilot study,” presented at the APASL 2014, Brisbane, Australia, Mar. 12–15, 2014.

  • Evaluation of ultrasound combined with chitosan for control of weight and local fat in mice


    Ai-Ho Liao, Wan-Chun Ma, and Ming-Fang Wu, “Evaluation of ultrasound combined with chitosan for control of weight and local fat in mice,” Ultrasound in Medicine and Biology, vol. 39, no. 10, pp. 1794–1803, 2013.

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  • In vivo measurement of liver elasticity on mice using a single element preclinical ultrasound system


    Chia-Lun Yeh, Bo-Rong Chen, Po-Ling Kuo, and Pai-Chi Li, “In vivo measurement of liver elasticity on mice using a single element preclinical ultrasound system,” presented at the ICBMU 2013, Taipei, Taiwan, Oct. 22–23, 2013.

  • Ischemic postconditioning-mediated miRNA-21 protects against cardiac ischemia/reperfusion injury via PTEN/Akt pathway


    Ying-feng Tu, Lin Wan, Yu-hua Fan, Ke-zheng Wang, Li-hong Bu, Tao Huang, Zhen Cheng, and Bao-zhong Shen, “Ischemic postconditioning-mediated miRNA-21 protects against cardiac ischemia/reperfusion injury via PTEN/Akt pathway,” PLOS ONE, vol. 8, no. 10, pp. 18–21, 2013.

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  • A novel use of chitosan combines with ultrasound for body weight and local fat controlled in mice


    Ai-Ho Liao, and Wan-Chun Ma, “A novel use of chitosan combines with ultrasound for body weight and local fat controlled in mice,” presented at the WMIC 2013, Savannah, Georgia, Sept. 18–21, 2013.

  • The study of absorption efficiency of microbubbles combines with ultrasound on skin treatment


    Ai-Ho Liao, and Wan-Chun Ma, “The study of absorption efficiency of microbubbles combines with ultrasound on skin treatment,” presented at the WMIC 2013, Savannah, Georgia, Sept. 18–21, 2013.

  • Complementary coded excitation for improvement of Doppler sensitivity in pre-clinical ultrasound imaging system


    Che-Chou Shen, and Gency Jeng, “Complementary coded excitation for improvement of Doppler sensitivity in pre-clinical ultrasound imaging system,” presented at the EMIM 2013, Torino, Italy, May 26–28, 2013.

  • To investigate the progression of myocardial infarction by echocardiographic assessment


    Bo-Jhih Pan, Ming-Sian Jiang, Chan-Jung Liang, Wen-Ping Chen, Pai-Chi Li, and Yuh-Lien Chen, “To investigate the progression of myocardial infarction by echocardiographic assessment,” presented at the WFUMB 2013, São Paulo, Brazil, May 2–5, 2013.

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  • Using Prospect high resolution imaging system to monitor cardiac function in post myocardial infarct mice treated with or without a TGFβ inhibitor


    Wen-Pin Chen, Lung-Chun Lin, and Pai-Chi Li, “Using Prospect high resolution imaging system to monitor cardiac function in post myocardial infarct mice treated with or without a TGFβ inhibitor,” presented at the WFUMB 2013, São Paulo, Brazil, May 2–5, 2013.

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  • Enhanced delivery of gold nanoparticles by acoustic cavitation for photoacoustic imaging and photothermal therapy


    Yu-Hsin Wang, Ai-Ho Liao, Jia-Yu Lin, Cheng-Ru Lee, Cheng-Ham Wu, Tzu-Min Liu, Churng-Ren Wang, and Pai-Chi Li, “Enhanced delivery of gold nanoparticles by acoustic cavitation for photoacoustic imaging and photothermal therapy,” presented at the SPIE Photonic West 2013, San Francisco, California, Feb. 2–7, 2013.

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  • Investigation on anisotropy of elastic properties in tendon using shear wave elasticity imaging


    Chia-Lun Yeh, Yae-Lin Sheu, Po-Ling Kuo, and Pai-Chi Li, “Investigation on anisotropy of elastic properties in tendon using shear wave elasticity imaging,” presented at the IEEE International Ultrasonics Symposium (IUS), Dresden, Germany, Oct. 7–10, 2012.

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  • Dynamic observation on rabbit ear hypertrophic scar formation with high frequency ultrasound biomicroscopy


    Yu-Fang You, Zhi-Gang Wang, Yuan-Yi Zheng, Wen-Yan Li, and Cheng-Cheng Niu, “Dynamic observation on rabbit ear hypertrophic scar formation with high frequency ultrasound biomicroscopy,” (in Chinese) Chinese Journal of Medical Imaging Technology, vol. 28, no. 12, pp. 2122–2126, 2012.
    游玉芳、王志剛、鄭元義、李文艷、牛誠誠,〈高頻超聲生物顯微鏡動態觀測兔耳增生性癇痕形成〉,《中國醫學影像技術》,第28卷第12期,頁2122–2126,2012年。

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  • Estimating the delivery efficiency of drug-loaded microbubbles in cancer cells with ultrasound and bioluminescence imaging


    Ai-Ho Liao, Ying-Kai Li, Wei-Jiunn Lee, Ming-Fang Wu, Hao-Li Liu, and Min-Liang Kuo, “Estimating the delivery efficiency of drug-loaded microbubbles in cancer cells with ultrasound and bioluminescence imaging,” Ultrasound in Medicine and Biology, vol. 38, no. 11, pp. 1938–1948, 2012.

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  • Prodigy

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  • Angle-Independent Blood Flow Velocity Measurement with Ultrasound Speckle Decorrelation Analysis


    Yongchao Wang, Wenkai Chen, Yetao He and Jianbo Tang, “Angle-Independent Blood Flow Velocity Measurement with Ultrasound Speckle Decorrelation Analysis,” IEEE Transactions on Medical Imaging, vol. 44, no. 5, pp. 2283–2294, 2025.

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  • Inhibition of p70 Ribosomal S6K1 Protects the Myocardium against Ischemia/Reperfusion-Induced Necrosis through Downregulation of RIP3


    Hui Shang, Jinjin Shi, Jun Zhu, Yunfeng Guo, and Xiaoyan Wang, “Inhibition of p70 Ribosomal S6K1 Protects the Myocardium against Ischemia/Reperfusion-Induced Necrosis through Downregulation of RIP3,” Front. Biosci, vol. 30, no. 1, Art. no. 26186, 2025.

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  • Enhancing Hybrid Exoskeleton Performance With Spatially Distributed Asynchronous Stimulation and Ultrasound Imaging-Based Fatigue Measurements


    Ashwin Iyer, Vidisha Ganesh, Mayank Singh, William Filer, Christine Cleveland, and Nitin Sharma, “Enhancing Hybrid Exoskeleton Performance With Spatially Distributed Asynchronous Stimulation and Ultrasound Imaging-Based Fatigue Measurements,” IEEE Transactions on Neural Systems and Rehabilitation Engineering, vol. 33, pp. 2542–2555, 2025.

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  • Adaptive Singular Value Decomposition-Based Hyperecho Suppression for Diagnostic Power Doppler Ultrasound Image Processing


    Yongchao Wang, Yang Liu, Xingzhao Liu, Ye Zhang, Weicheng Li, Yaokun He, and Jianbo Tan, “Adaptive Singular Value Decomposition-Based Hyperecho Suppression for Diagnostic Power Doppler Ultrasound Image Processing,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 72, no. 9, pp. 1213–1221, 2025.

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  • Muscle injury detection based on ultrasound/photoacoustic dual-mode shear wave elastography


    Gang Li, Zhigang Lei, Yuelin Han, Zheng Yuan, Zhiping Yu, and Mingjian Sun, “Muscle injury detection based on ultrasound/photoacoustic dual-mode shear wave elastography,” presented at the Proc. SPIE 13799, Second Conference of Young Scientists of the Chinese Society of Optical Engineering, 137992D, 2025.

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  • Design of a Low-Cost, High-Resolution Underwater Acoustic Imager With Integrated Deep Learning Enhancement


    Jheng-Wei Hu, Men-Tzung Lo, Chun-Yi Chen, Cheng-Shun Chuang, Chia-Lun Yeh, Fang-Bin Liu, Ping-Yang Liu, Chin-Shu Yao, Bo-Cheng Lai, Hsueh-Cheng Nick Wang, Tzu-Hsien Sang, and Geng-Shi Jeng, “Design of a Low-Cost, High-Resolution Underwater Acoustic Imager With Integrated Deep Learning Enhancement,” IEEE Sensors Journal, vol. 25, no. 23, pp. 43256–43266, 2025.

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  • Quantitative Ultrasound Imaging with Coded Excitation for Simultaneous Monitoring of High-Intensity Focused Ultrasound (HIFU) Therapy


    Liang Lee and Che-Chou Shen, “Quantitative Ultrasound Imaging with Coded Excitation for Simultaneous Monitoring of High-Intensity Focused Ultrasound (HIFU) Therapy,” presented at the 2025 IEEE International Ultrasonics Symposium (IUS), pp. 1–4, 2025.

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  • Enhanced Needle Visualization using Ultrasonic Synthetic Aperture Imaging with Specular CNN Modeling


    Liang-Chun Tung and Che-Chou Shen, “Enhanced Needle Visualization using Ultrasonic Synthetic Aperture Imaging with Specular CNN Modeling,” presented at the 2025 IEEE International Ultrasonics Symposium (IUS), pp. 1–4, 2025.

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  • Convolutional sparse coding for compressed sensing photoacoustic CT reconstruction with partially known support


    Zezheng Qin, Yiming Ma, Lingyu Ma, Guangxing Liu and Mingjian Sun, “Convolutional sparse coding for compressed sensing photoacoustic CT reconstruction with partially known support,” Biomedical Optics Express, vol. 15, no. 2, p. 524, 2024.

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  • Ultrafast Doppler Imaging for Early Detection of Synovitis in Rheumatoid Arthritis


    Kuo-Lung Lai, Min-Chieh Tsai and Pai-Chi Li, “Ultrafast Doppler Imaging for Early Detection of Synovitis in Rheumatoid Arthritis,” Ultrasound in Medicine & Biology, vol. 50, no. 4, pp. 484–493, 2024.

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  • Ultrasound monitoring of simultaneous High-Intensity focused ultrasound (HIFU) therapy using Minimum-Peak-Sidelobe coded excitation


    Che-Chou Shen and Nien-Hung Wu, “Ultrasound monitoring of simultaneous High-Intensity focused ultrasound (HIFU) therapy using Minimum-Peak-Sidelobe coded excitation,” Ultrasonics, vol. 138, Art. no. 107224, 2024.

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  • Fourier-Based Fast 3-D Ultrasound Imaging Using Row–Column-Addressed 2-D Arrays


    Shang-Ching Lin and Pai-Chi Li, “Fourier-Based Fast 3-D Ultrasound Imaging Using Row–Column-Addressed 2-D Arrays,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 71, no. 1, pp. 85–101, 2024.

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  • Ultrasound B-mode Visualization of Imperceptible Subwavelength Vibration in Magnetomotive Ultrasound Imaging


    Wei-Hsiang Shen, Tzu-Min Yeh, Mei-Yi Liao and Meng-Lin Li, “Ultrasound B-mode Visualization of Imperceptible Subwavelength Vibration in Magnetomotive Ultrasound Imaging,” Vibration, vol. 7, no. 3, pp. 764–775, 2024.

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  • Detection of near-surface defects in viscoelastic material based on focused ultrasound thermal effects


    Mengyu Han, Huifeng Zheng, Yumeng Gao, Zhuangxin Zhou and Xiangchen Liu, “Detection of near-surface defects in viscoelastic material based on focused ultrasound thermal effects,” Ultrasonics, vol. 143, Art. no. 107415, 2024.

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  • Ultrasound-Compatible Electrode for Functional Electrical Stimulation


    Sunho Moon, Xiangming Xue, Vidisha Ganesh, Darpan Shukla, Benjamin C. Kreager, Qianqian Cai, Huaiyu Wu, Yong Zhu, Nitin Sharma and Xiaoning Jiang, “Ultrasound-Compatible Electrode for Functional Electrical Stimulation,” Biomedicines, vol. 12, no. 8, p. 1741, 2024.

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  • Real-Time Ultrasound Imaging of a Human Muscle to Optimize Shared Control in a Hybrid Exoskeleton


    Ashwin Iyer, Ziyue Sun, Krysten Lambeth, Mayank Singh, Christine Cleveland, and Nitin Sharma, “Real-Time Ultrasound Imaging of a Human Muscle to Optimize Shared Control in a Hybrid Exoskeleton,” IEEE Transactions on Robotics, vol. 40, pp. 4322–4336, 2024.

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  • Photoacoustic thermal-strain measurement towards noninvasive and accurate temperature mapping in photothermal therapy


    Zezheng Qin, Puxiang Lai and Mingjian Sun, “Photoacoustic thermal-strain measurement towards noninvasive and accurate temperature mapping in photothermal therapy,” Photoacoustics, vol. 40, Art. no. 100651, 2024.

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  • AnkleImage - An ultrafast ultrasound image dataset to understand the ankle joint muscle contractility


    Qiang Zhang, Noor Hakam, Oluwasegun Akinniyi, Ashwin Iyer, Xuefeng Bao and Nitin Sharma, “AnkleImage - An ultrafast ultrasound image dataset to understand the ankle joint muscle contractility,” Scientific Data, vol. 11, no. 1, Art. no. 1439, 2024.

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  • Nonlinear System Identification of Tremors Dynamics: A Data-driven Approximation Using Koopman Operator Theory


    Xiangming Xue, Ashwin Iyer, Daniel Roque, and Nitin Sharma, “Nonlinear System Identification of Tremors Dynamics: A Data-driven Approximation Using Koopman Operator Theory,” presented at the 2023 11th International IEEE/EMBS Conference on Neural Engineering (NER), Baltimore, MD, USA, pp. 1–4, 2023.

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  • Towards ultrasound imaging-based closed-loop peripheral nerve stimulation for tremor suppression


    Nitin Sharma, Xiangming Xue, Ashwin Iyer, Xiaoning Jiang and Daniel Roque, “Towards ultrasound imaging-based closed-loop peripheral nerve stimulation for tremor suppression,” Current Opinion in Biomedical Engineering, vol. 28, Art. no. 100484, 2023.

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  • A Dual-Mode Spherically Focused Theranostic Phased Array for CNS Application


    Chun Fu, Tzu-Tsen Hsieh, and Hao-Li Liu, “A Dual-Mode Spherically Focused Theranostic Phased Array for CNS Application,” presented at the 2023 IEEE International Ultrasonics Symposium (IUS), Montreal, QC, Canada, pp. 1–4, 2023.

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  • Multi-Wavelength Photoacoustic Temperature Feedback Based Photothermal Therapy Method and System


    Yiming Ma, Yang Liu, Zhigang Lei, Zezheng Qin, Yi Shen and Mingjian Sun, “Multi-Wavelength Photoacoustic Temperature Feedback Based Photothermal Therapy Method and System,” Pharmaceutics, vol. 15, no. 2, p. 555, 2023.

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  • Improved source localization in passive acoustic mapping using delay-multiply-and-sum beamforming with virtually augmented aperture


    Che-Chou Shen, You-An Chen, and Hsin-Yu Ku, “Improved source localization in passive acoustic mapping using delay-multiply-and-sum beamforming with virtually augmented aperture,” Ultrasonics, vol. 135, Art. no. 107125, 2023.

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  • Visual Perception and Convolutional Neural Network-Based Robotic Autonomous Lung Ultrasound Scanning Localization System


    Boheng Zhang, Haibo Cong, Yi Shen and Mingjian Sun, “Visual Perception and Convolutional Neural Network-Based Robotic Autonomous Lung Ultrasound Scanning Localization System,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 70, no. 9, pp. 961–974, 2023.

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  • A neural network estimation model based light dose control method and system for low-temperature photothermal therapy


    Yiming Ma, Zhigang Lei, Dongjian Wu, Yi Shen and Mingjian Sun, “A neural network estimation model based light dose control method and system for low-temperature photothermal therapy,” Biomedical Signal Processing and Control, vol. 85, Art. no. 104935, 2023.

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  • Mild-temperature photothermal treatment method and system based on photoacoustic temperature measurement and control


    Yiming Ma, Yang Liu, Zezheng Qin, Yi Shen and Mingjian Sun, “Mild-temperature photothermal treatment method and system based on photoacoustic temperature measurement and control,” Biomedical Signal Processing and Control, vol. 79, Art. no. 104056, 2023.

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  • Effects of acute resistance exercise on myocardial perfusion and left ventricular energy waste: Comparisons between habitually resistance-trained only and combined exercise-trained populations


    Chang-Lun Shu, Shiou-Shu Huang, Lian-Yu Lin, and Hsin-Fu Lin, “Effects of acute resistance exercise on myocardial perfusion and left ventricular energy waste: Comparisons between habitually resistance-trained only and combined exercise-trained populations,” Physical Education Journal, vol. 56, no. 3, p. 285, 2023.

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  • Visual Perception-Guided Robotic Arm Automatic Ultrasound Scanning 3D Imaging System


    Boheng Zhang, Kui Xu, Yunshu Xue, Yi Shen and Mingjian Sun, “Visual Perception-Guided Robotic Arm Automatic Ultrasound Scanning 3D Imaging System,” Ultrasonics, 2023.

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  • Oxygen-loaded microbubble-mediated sonoperfusion and oxygenation for neuroprotection after ischemic stroke reperfusion


    Yi-Ju Ho, Hsiang-Lung Cheng, Lun-De Liao, Yu-Chun Lin, Hong-Chieh Tsai and Chih-Kuang Yeh, “Oxygen-loaded microbubble-mediated sonoperfusion and oxygenation for neuroprotection after ischemic stroke reperfusion,” Biomaterials Research, vol. 27, no. 1, Art. no. 65, 2023.

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  • Ultrasound Echogenicity as an Indicator of Muscle Fatigue during Functional Electrical Stimulation


    Qiang Zhang, Ashwin Iyer, Krysten Lambeth, Kang Kim and Nitin Sharma, “Ultrasound Echogenicity as an Indicator of Muscle Fatigue during Functional Electrical Stimulation,” Sensors, vol. 22, no. 1, p. 335, 2022.

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  • Transmit Delay and Standard Deviation Beamforming to Enhance Specular Reflections in Synthetic Transmit Aperture Imaging


    Cheng-Hao Lin and Che-Chou Shen, “Transmit Delay and Standard Deviation Beamforming to Enhance Specular Reflections in Synthetic Transmit Aperture Imaging,” presented at the IEEE International Ultrasonics Symposium (IUS), Venice, Italy, pp. 1–4, 2022.

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  • Ultrasound-Based Sensing and Control of Functional Electrical Stimulation for Ankle Joint Dorsiflexion: Preliminary Study


    Qiang Zhang, Ashwin Iyer, and Nitin Sharma, “Ultrasound-Based Sensing and Control of Functional Electrical Stimulation for Ankle Joint Dorsiflexion: Preliminary Study,” presented at the International Symposium on Wearable Robotics, Wearable Robotics: Challenges and Trends, Biosystems & Biorobotics 27, pp. 307–311, 2022.

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  • Noninvasive photoacoustic computed tomography/ultrasound imaging to identify high-risk atherosclerotic plaques


    Xuewei Liu, Rongkang Gao, Chiyun Chen, Xiaobo Li, Chen Yu, Yejia Chen, Hongbin Liang, Min Xiao, Lei Dai, Shifeng Qiu, Xiaoyu Xin, Liang Song, Jinbin Liu, Chengbo Liu and Jiancheng Xiu, “Noninvasive photoacoustic computed tomography/ultrasound imaging to identify high-risk atherosclerotic plaques,” European Journal of Nuclear Medicine and Molecular Imaging, vol. 49, no. 13, pp. 4601–4615, 2022.

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  • A Hybrid Knee Exoskeleton Using Real-Time Ultrasound-Based Muscle Fatigue Assessment


    Z. Sheng, A. Iyer, Z. Sun, K. Kim and N. Sharma, “A Hybrid Knee Exoskeleton Using Real-Time Ultrasound-Based Muscle Fatigue Assessment,” IEEE/ASME Transactions on Mechatronics, vol. 27, no. 4, pp. 1854–1862, 2022.

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  • Golay-Encoded Ultrasound Monitoring of Simultaneous High-Intensity Focused Ultrasound Treatment: A Phantom Study


    Che-Chou Shen, Ri-Cheng Lin and Nien-Hung Wu, “Golay-Encoded Ultrasound Monitoring of Simultaneous High-Intensity Focused Ultrasound Treatment: A Phantom Study,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 69, no. 4, pp. 1370–1381, 2022.

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  • Fused ultrasound and electromyography-driven neuromuscular model to improve plantarflexion moment prediction across walking speeds


    Qiang Zhang, Natalie Fragnito, Jason R. Franz and Nitin Sharma, “Fused ultrasound and electromyography-driven neuromuscular model to improve plantarflexion moment prediction across walking speeds,” Journal of NeuroEngineering and Rehabilitation, vol. 19, no. 1, Art. no. 86, 2022.

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  • Vascular responses of penetrating vessels during cortical spreading depolarization with ultrasound dynamic ultrafast Doppler imaging


    Bao-Yu Hsieh, Yu-Chieh Jill Kao, Ning Zhou, Yi-Pei Lin, Yu-Ying Mei, Sung-Yu Chu and Dong-Chuan Wu, “Vascular responses of penetrating vessels during cortical spreading depolarization with ultrasound dynamic ultrafast Doppler imaging,” Frontiers in Neuroscience, vol. 16, Art. no. 1015843, 2022.

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  • A deep learning method to predict ankle joint moment during walking at different speeds with ultrasound imaging: A framework for assistive devices control


    Qiang Zhang, Natalie Fragnito, Xuefeng Bao and Nitin Sharma, “A deep learning method to predict ankle joint moment during walking at different speeds with ultrasound imaging: A framework for assistive devices control,” Wearable Technologies, vol. 3, Art. no. e20, 2022.

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  • Polarization microwave-induced thermoacoustic imaging for quantitative characterization of deep biological tissue microstructures


    Yujing Li, Shanxiang Zhang, Linghua Wu, Zhongwen Cheng, Zhenhui Zhang, Haohao Wang, Shuxiang Zhao, Mingyang Ren, Sihua Yang, Da Xing, and Huan Qin, “Polarization microwave-induced thermoacoustic imaging for quantitative characterization of deep biological tissue microstructures,” Photonics Research, vol. 10, no. 5, p. 1297, 2022.

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  • Ultrasound Imaging-Based Closed-Loop Control of Functional Electrical Stimulationfor Drop Foot Correction


    Qiang Zhang, Krysten Lambeth, Ashwin Iyer, Ziyue Sun and Nitin Sharma, “Ultrasound Imaging-Based Closed-Loop Control of Functional Electrical Stimulationfor Drop Foot Correction,” IEEE Transactions on Control Systems Technology, vol. 31, no. 3, pp. 989–1005, 2022.

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  • Ultrafast Ultrasound-Derived Muscle Strain Measure Correlates with Carotid Local Pulse Wave Velocity in Habitual Resistance-Trained Individuals


    Hsin-Fu Lin, Yi-Hung Liao and Pai-Chi Li, “Ultrafast Ultrasound-Derived Muscle Strain Measure Correlates with Carotid Local Pulse Wave Velocity in Habitual Resistance-Trained Individuals,” Applied Sciences, vol. 11, no. 18, p. 8783, 2021.

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  • Ultra-High-Frame-Rate Ultrasound Monitoring of Muscle Contractility Changes Due to Neuromuscular Electrical Stimulation


    Zhiyu Sheng, Nitin Sharma and Kang Kim, “Ultra-High-Frame-Rate Ultrasound Monitoring of Muscle Contractility Changes Due to Neuromuscular Electrical Stimulation,” Annals of Biomedical Engineering, vol. 49, no. 1, pp. 262–275, 2021.

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  • DMAS Beamforming with Complementary Subset Transmit for Ultrasound Coherence-Based Power Doppler Detection in Multi-Angle Plane-Wave Imaging


    Che-Chou Shen and Yen-Chen Chu, “DMAS Beamforming with Complementary Subset Transmit for Ultrasound Coherence-Based Power Doppler Detection in Multi-Angle Plane-Wave Imaging,” Sensors, vol. 21, no. 14, p. 4856, 2021.

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  • Elevational motion estimation for 3D ultrasound with machine learning and a speckle generating gel pad


    Ching-Yen Lee, U-Wai Lok and Pai-Chi Li, “Elevational motion estimation for 3D ultrasound with machine learning and a speckle generating gel pad,” presented at the Proc. SPIE 11792, International Forum on Medical Imaging in Asia 2021, 117920U, 20 April 2021.

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  • Closed-loop photothermal therapy system based on photoacoustic and ultrasonic dual-mode temperature feedback


    Yiming Ma, Zhigang Lei, Yuanyuan Gao and Mingjian Sun, “Closed-loop photothermal therapy system based on photoacoustic and ultrasonic dual-mode temperature feedback,” presented at the IEEE International Ultrasonics Symposium (IUS), pp. 1–4, 2021.

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  • Stereoscopic photoacoustic imaging of radial artery for preoperative evaluation of coronary intervention


    Tengsen Qiu, Yihao Duan and Zhongwen Cheng, “Stereoscopic photoacoustic imaging of radial artery for preoperative evaluation of coronary intervention,” Applied Physics Express, vol. 14, no. 5, p. 052005, 2021.

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  • Computationally efficient minimum-variance baseband delay-multiply-and-sum beamforming for adjustable enhancement of ultrasound image resolution


    Che-Chou Shen, “Computationally efficient minimum-variance baseband delay-multiply-and-sum beamforming for adjustable enhancement of ultrasound image resolution,” Ultrasonics, vol. 112, Art. no. 106345, 2021.

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  • Intelligent photothermal treatment method based on photoacoustic and photothermal probe assistance


    Yiming Ma, Liyong Ma, Yuanyuan Gao and Mingjian Sun, “Intelligent photothermal treatment method based on photoacoustic and photothermal probe assistance,” presented at the Proc. SPIE 11781, 4th Optics Young Scientist Summit (OYSS 2020), 1178121, 28 Feb. 2021.

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  • Spherical-matching hyperbolic-array photoacoustic computed tomography


    Yihao Duan, Zhongwen Cheng, Tengsen Qiu, Liewei Wen and Kedi Xiong, “Spherical-matching hyperbolic-array photoacoustic computed tomography,” Journal of Biophotonics, vol. 14, no. 6, Art. no. e202100023, 2021.

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  • Laser-Generated Leaky Acoustic Wave Imaging for Interventional Guidewire Guidance


    Geng-Shi Jeng, Yi-An Wang, Ping-Yang Liu and Pai-Chi Li, “Laser-Generated Leaky Acoustic Wave Imaging for Interventional Guidewire Guidance,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 68, no. 7, pp. 2496–2506, 2021.

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  • An Excitation-Reception Collinear Probe for Ultrasonic, Photoacoustic, and Thermoacoustic Tri-Modal Volumetric Imaging


    Zhongwen Cheng, Linghua Wu, Tengsen Qiu, Yihao Duan, Huan Qin, Jun Hu and Sihua Yang, “An Excitation-Reception Collinear Probe for Ultrasonic, Photoacoustic, and Thermoacoustic Tri-Modal Volumetric Imaging,” IEEE Transactions on Medical Imaging, vol. 40, no. 12, pp. 3498–3506, 2021.

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  • Prediction of Ankle Dorsiflexion Moment by Combined Ultrasound Sonography and Electromyography


    Qiang Zhang, Kang Kim and Nitin Sharma, “Prediction of Ankle Dorsiflexion Moment by Combined Ultrasound Sonography and Electromyography,” IEEE Transactions on Neural Systems and Rehabilitation Engineering, vol. 28, no. 1, pp. 318–327, 2020.

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  • Ultrasound DMAS beamforming for estimation of tissue speed of sound in multi-angle plane-wave imaging


    Kuan-Lin Tu, Che-Chou Shen and Yen-Chen Chu, “Ultrasound DMAS beamforming for estimation of tissue speed of sound in multi-angle plane-wave imaging,” presented at the IEEE International Ultrasonics Symposium (IUS), pp. 1–4, 2020.

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  • Analysis of Tremor During Grasp Using Ultrasound Imaging: Preliminary Study


    Ashwin Iyer, Zhiyu Sheng, Qiang Zhang, Kang Kim and Nitin Sharma, “Analysis of Tremor During Grasp Using Ultrasound Imaging: Preliminary Study,” presented at the 2020 8th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob), New York, USA. Nov 29 - Dec 1, pp. 533–538, 2020.

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  • Radiotherapy dose characterization of gel dosimetry using shear wave elasticity imaging


    Wei‐Huan Xie, Chun‐Ting Su, Yu‐Chieh Jill Kao, Tung‐Hao Chang, Yuan‐Jen Chang, Chun‐Hsu Yao and Bao‐Yu Hsieh, “Radiotherapy dose characterization of gel dosimetry using shear wave elasticity imaging,” Medical Physics, vol. 47, no. 3, pp. 1404–1410, 2020.

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  • Estimation of ultrasound echogenicity map from B-mode images using convolutional neural network


    Jui-En Yang, Che-Chou Shen and Ri-Cheng Lin, “Estimation of ultrasound echogenicity map from B-mode images using convolutional neural network,” presented at the IEEE International Ultrasonics Symposium (IUS), pp. 1–4, 2020.

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  • Volitional Contractility Assessment of Plantar Flexors by Using Non-invasive Neuromuscular Measurements


    Qiang Zhang, Ashwin Iyer, Kang Kim and Nitin Sharma, “Volitional Contractility Assessment of Plantar Flexors by Using Non-invasive Neuromuscular Measurements,” presented at the 2020 8th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob), New York, USA. Nov 29 - Dec 1, pp. 515–520, 2020.

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  • Evaluation of Non-Invasive Ankle Joint Effort Prediction Methods for Use in Neurorehabilitation Using Electromyography and Ultrasound Imaging


    Qiang Zhang, Ashwin Iyer, Kang Kim and Nitin Sharma, “Evaluation of Non-Invasive Ankle Joint Effort Prediction Methods for Use in Neurorehabilitation Using Electromyography and Ultrasound Imaging,” IEEE Transactions on Biomedical Engineering, vol. 68, no. 3, pp. 1044–1055, 2020.

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  • Correlation-Based Doppler-Angle Estimation with Plane-Wave Excitation


    U-Wai Lok, Fang-Yu Lin, Chia-Lun Yeh and Pai-Chi Li, “Correlation-Based Doppler-Angle Estimation with Plane-Wave Excitation,” Informatics in Medicine Unlocked, vol. 19, Art. no. 100315, 2020.

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  • Estimation of Ultrasound Echogenicity Map from B-Mode Images Using Convolutional Neural Network


    Che-Chou Shen and Jui-En Yang, “Estimation of Ultrasound Echogenicity Map from B-Mode Images Using Convolutional Neural Network,” Sensors, vol. 20, no. 17, p. 4931, 2020.

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  • Dual-Frequency Chirp Excitation for Passive Cavitation Imaging in the Brain


    Hsiang-Ching Lin, Ching-Hsiang Fan, Yi-Ju Ho and Chih-Kuang Yeh, “Dual-Frequency Chirp Excitation for Passive Cavitation Imaging in the Brain,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 67, no. 6, pp. 1127–1140, 2020.

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  • Synthetic transmit aperture beamforming for sound velocity estimation using channel-domain differential phase gradient–A phantom study


    Che-Chou Shen, Sheng-Hsuan Hsiao, and Yen-Chung Lin, “Synthetic transmit aperture beamforming for sound velocity estimation using channel-domain differential phase gradient–A phantom study,” Ultrasonics, vol. 94, pp. 183–191, 2019.

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  • Ankle Dorsiflexion Strength Monitoring by Combining Sonomyography and Electromyography


    Qiang Zhang, Zhiyu Sheng, Frank Moore-Clingenpeel, Kang Kim, Nitin Sharma, “Ankle Dorsiflexion Strength Monitoring by Combining Sonomyography and Electromyography,” presented at the ICORR, pp. 240–245, 2019.

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  • Synchronized Optical and Acoustic Droplet Vaporization for Effective Sonoporation


    Wei-Wen Liu, Sy-Han Huang, Pai-Chi Li, “Synchronized Optical and Acoustic Droplet Vaporization for Effective Sonoporation,” Pharmaceutics, vol. 11, no. 6, p. 279, 2019.

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  • Real-time interleaved photoacoustic and ultrasound imaging for guiding interventional procedures


    Weicheng Zhang, Jiandong Li, Sihua Yang, “Real-time interleaved photoacoustic and ultrasound imaging for guiding interventional procedures,” Applied Acoustics, vol. 156, pp. 1–6, 2019.

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  • Quantitative Reconstruction of Absorption Coefficients for Photoacoustic Tomography


    Yang Liu, Mingjian Sun, Ting Liu, Yiming Ma, Depeng Hu, Chao Li and Naizhang Feng, “Quantitative Reconstruction of Absorption Coefficients for Photoacoustic Tomography,” Applied Sciences, vol. 9, no. 6, p. 1187, 2019.

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  • Ultrasound Baseband Delay-Multiply-and-Sum (BB-DMAS) nonlinear beamforming


    Che-Chou Shen and Pei-Ying Hsieh, “Ultrasound Baseband Delay-Multiply-and-Sum (BB-DMAS) nonlinear beamforming,” Ultrasonics, vol. 96, pp. 165–174, 2019.

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  • Quantitative Assessment of Changes in Muscle Contractility Due to Fatigue During NMES: An Ultrasound Imaging Approach


    Zhiyu Sheng, Nitin Sharma and Kang Kim, “Quantitative Assessment of Changes in Muscle Contractility Due to Fatigue During NMES: An Ultrasound Imaging Approach,” IEEE Transactions on Biomedical Engineering (Early Access), vol. 67, no. 3, pp. 832–841, 2019.

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  • Toward Real Time Backward-Mode Pulsed Magnetomotive Ultrasound


    Wei-Hsiang Shen and Meng-Lin Li, “Toward Real Time Backward-Mode Pulsed Magnetomotive Ultrasound,” presented at the IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, pp. 396–398, 2019.

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  • Improved Backward Mode Pulsed Magnetomotive Ultrasound via Pre-magnetization of Superparamagnetic Iron Oxide Nanoparticles


    Hong-Wei Wang, Chih-Chia Huang and Meng-Lin Li, “Improved Backward Mode Pulsed Magnetomotive Ultrasound via Pre-magnetization of Superparamagnetic Iron Oxide Nanoparticles,” presented at the IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, pp. 2387–2389, 2019.

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  • Golay-Encoded Pulse-Inversion Subtraction for Real-Time Ultrasound Monitoring of HIFU Therapy


    Guan-Heng Lai, Pai-Chi Li and Che-Chou Shen, “Golay-Encoded Pulse-Inversion Subtraction for Real-Time Ultrasound Monitoring of HIFU Therapy,” presented at the IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, pp. 127–130, 2019.

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  • Detection of KCl Induced Cortical Spreading Depolarization (CSD) with Dynamic Ultrafast Doppler


    Ning Zhou, Yu-Chieh Jill Kao, Yu-Ying Mei, Yi-Pei Lin, Dong-Chuan Wu and Bao-Yu Hsieh, “Detection of KCl Induced Cortical Spreading Depolarization (CSD) with Dynamic Ultrafast Doppler,” presented at the IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, pp. 1330–1333, 2019.

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  • Monitoring of Vascular Response to Peri-Infarct Depolarization (PID) in Photothrombotic Stroke Animal Model


    Yu-Chieh Jill Kao and Bao-Yu Hsieh, “Monitoring of Vascular Response to Peri-Infarct Depolarization (PID) in Photothrombotic Stroke Animal Model,” presented at the IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, pp. 235–238, 2019.

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  • A Flexible Speckle Reduction Strategy using Thomson’s Multitaper in High-order DMAS Beamforming


    Che-Chou Shen and Pei-Ying Hsieh, “A Flexible Speckle Reduction Strategy using Thomson’s Multitaper in High-order DMAS Beamforming,” presented at the IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, pp. 1290–1293, 2019.

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  • Linear array-based real-time photoacoustic imaging system with a compact coaxial excitation handheld probe for noninvasive sentinel lymph node mapping


    Mucong Li, Chengbo Liu, Xiaojing Gong, Rongqin Zheng, Yuanyuan Bai, Muyue Xing, Xuemin Du, Xiaoyang Liu, Jing Zeng, Riqiang Lin, Huichao Zhou, Shouju Wang, Guangming Lu, Wen Zhu, Chihua Fang, and Lian Song, “Linear array-based real-time photoacoustic imaging system with a compact coaxial excitation handheld probe for noninvasive sentinel lymph node mapping,” Biomedical Optics Express, vol. 9, no. 4, p. 1408, 2018.

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  • Large Depth Focus-Tunable Photoacoustic Tomography Based On Clinical Ultrasound Array Transducer


    Ruian Liu, Liangzhong Xiang, Da Xing, Jiandong Li, Huan Qin, Weicheng Zhang, and Sihua Yang, “Large Depth Focus-Tunable Photoacoustic Tomography Based On Clinical Ultrasound Array Transducer,” Applied Physics Letters, vol. 113, no. 14, Art. no. 141102, 2018.

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  • Ultrafast Doppler Observation in Rat Stroke Model-Comparison with High Field Magnetic Resonance Imaging


    Yu-Chieh Jill Kao and Bao-Yu Hsieh, “Ultrafast Doppler Observation in Rat Stroke Model-Comparison with High Field Magnetic Resonance Imaging,” presented at the IEEE International Ultrasonics Symposium (IUS), pp. 1–4, 2018.

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  • Laser Generated Leaky Acoustic Waves for Needle Visualization


    Kai-Wen Wu, Yi-An Wang and Pai-Chi Li, “Laser Generated Leaky Acoustic Waves for Needle Visualization,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 65, no. 4, pp. 546–556, 2018.

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  • Microbeamforming With Error Compensation


    U-Wai Lok and Pai-Chi Li, “Microbeamforming With Error Compensation,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 65, no. 7, pp. 1153–1165, 2018.

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  • Photoacoustic Elasticity Imaging for Soft Tissue-mimicking Phantom


    Nai-Zhang Feng, Ying Fu, Tong Wang, and Ming-Jian Sun, “Photoacoustic Elasticity Imaging for Soft Tissue-mimicking Phantom,” presented at the International Conference on Photonics and Imaging in Biology and Medicine, Suzhou, China, September 26-28, p. W3A.117, 2017.

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  • Backward-mode ultrafast pulsed magnetomotive ultrasound


    Ming-Chen Lu, Jieh-Yuan Houng, Meng-Lin Li, “Backward-mode ultrafast pulsed magnetomotive ultrasound,” presented at the IEEE International Ultrasonics Symposium (IUS), Washington, DC, USA, September 6-9, p. 1, 2017.

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  • Needle guidance using laser generated leaky acoustic waves


    Yi-An Wang, U-Wai Lok, Pai-Chi Li, “Needle guidance using laser generated leaky acoustic waves,” presented at the IEEE International Ultrasonics Symposium (IUS), Washington, DC, USA, September 6-9, pp. 1–3, 2017.

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  • Compressed sensing in synthetic aperture photoacoustic tomography based on a linear-array ultrasound transducer


    Xiang-Wei Lin, Nai-Zhang Feng, Ya-Wei Qu, De-Ying Chen, Yi Shen, and Ming-Jian Sun, “Compressed sensing in synthetic aperture photoacoustic tomography based on a linear-array ultrasound transducer,” Chinese Optics Letters, vol. 15, no. 10, p. 101102, 2017.

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  • Monte Carlo light transport-based blood vessel quantification using linear array photoacoustic tomography


    Xiang-Wei Lin, Ming-Jian Sun, Nai-Zhang Feng, De-Peng Hu, and Yi Shen, “Monte Carlo light transport-based blood vessel quantification using linear array photoacoustic tomography,” Chinese Optics Letters, vol. 15, no. 11, p. 111701, 2017.

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  • Adaptive optimization of ultrasound beamforming sound velocity using sub-aperture differential phase gradient


    Che-Chou Shen, Hsiao-Chi Yang, “Adaptive optimization of ultrasound beamforming sound velocity using sub-aperture differential phase gradient,” Ultrasonics, vol. 79, pp. 52–59, 2017.

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  • Sound speed optimization for ultrasound beamforming using differential phase gradient between sub-apertures


    Che-Chou Shen, Hsiao-Chi Yang, Gency Jeng, “Sound speed optimization for ultrasound beamforming using differential phase gradient between sub-apertures,” presented at the IEEE International Ultrasonics Symposium (IUS), Tour, France, September 18-21, pp. 1–4, 2016.

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  • Autocorrelation-based generalized coherence factor for low-complexity adaptive beamforming


    Che-Chou Shen, Yong-Qi Xing and Gency Jeng, “Autocorrelation-based generalized coherence factor for low-complexity adaptive beamforming,” Ultrasonics, vol. 72, pp. 177–183, 2016.

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  • Transform-Based Channel-Data Compression to Improve the Performance of a Real-Time GPU-Based Software Beamformer


    U.-Wai Lok and Pai-Chi Li, “Transform-Based Channel-Data Compression to Improve the Performance of a Real-Time GPU-Based Software Beamformer,” IEEE Transactions on Ultrasonics, vol. 63, no. 3, pp. 369–380, 2016.

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  • Hybrid optoacoustic tomography and pulse-echo ultrasonography using concave arrays


    Merčep, E., Jeng, G., Morscher, S., Pai-Chi Li, Razansky, D., “Hybrid optoacoustic tomography and pulse-echo ultrasonography using concave arrays,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 62, no. 9, pp. 1651–1661, 2015.

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  • Low-complexity adaptive beamforming using autocorrelation-based generalized coherence factor


    Yong-Qi Xing, Shue-Han Jiang, Gency Jeng, Che-Chou Shen, “Low-complexity adaptive beamforming using autocorrelation-based generalized coherence factor,” presented at the IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, October 21-24, pp. 1–4, 2015.

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  • Ultrafast pulsed magnetomotive ultrasound imaging of sentinel lymph nodes: Small animal study


    Yu-Chun Huang, Jieh-Yuan Houng, Yi-Da Kang, San-Yuan Chen, Meng-Lin Li, “Ultrafast pulsed magnetomotive ultrasound imaging of sentinel lymph nodes: Small animal study,” presented at the IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, October 21-24, pp. 1–3, 2015.

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  • Linear array beamformation using virtual sub-wavelength receiving elements


    Shao-Yu Peng, Meng-Lin Li, “Linear array beamformation using virtual sub-wavelength receiving elements,” presented at the IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, October 21-24, pp. 1–3, 2015.

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  • Ultrafast plane wave imaging based pulsed magnetomotive ultrasound


    Pei-Hsien Ting, Yi-Da Kang, San-Yuan Chen, Meng-Lin Li, “Ultrafast plane wave imaging based pulsed magnetomotive ultrasound,” presented at the IEEE International Ultrasonics Symposium(IUS), Chicago Illinois, USA, September 3-6, pp. 456–458, 2014.

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  • Motion score for spectral quality control of optoacoustic-ultrasound data


    Jan Kukačka, Maximilian Bader, Dominik Jüstel and Vasilis Ntziachristos, “Motion score for spectral quality control of optoacoustic-ultrasound data,” Scientific Reports, vol. 16, no. 1, Art. no. 1325, 2026.

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  • Utility of photoacoustic patterns in intra-operative margin assessment of breast cancer post neoadjuvant chemotherapy


    Yonggeng Goh, Ghayathri Balasundaram, Hui Min Tan, Thomas Choudary Putti, Renzhe Bi, Mikael Hartman, Shaik Ahmad Buhari, Celene Wei Qi Ng, Su Ann Lui, Serene Si Ning Goh, Wei Qi Leong, Eric Fang, Swee Tian Quek, and Malini Olivo, “Utility of photoacoustic patterns in intra-operative margin assessment of breast cancer post neoadjuvant chemotherapy,” Photoacoustics, vol. 43, Art. no. 100701, 2025.

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  • Upconversion Nanoparticle-Covalent Organic Framework Core-shell Particles as Therapeutic Microrobots Trackable With Optoacoustic Imaging


    Dong Wook Kim, Paul Wrede, Andrés Rodríguez-Camargo, Yi Chen, Nihal Olcay Dogan, Chaim Glück, Bettina V. Lotsch, Daniel Razansky, and Metin Sitti, “Upconversion Nanoparticle-Covalent Organic Framework Core-shell Particles as Therapeutic Microrobots Trackable With Optoacoustic Imaging,” Advanced Materials, vol. 37, no. 49, Art. no. 2418425, 2025.

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  • Deciphering the spectra of breast cancer in multispectral optoacoustic tomography


    Maximilian Bader, Benedict E. Mc Larney, Katja Pinker, Jan Grimm, Dominik Jüstel, and Vasilis Ntziachristos, “Deciphering the spectra of breast cancer in multispectral optoacoustic tomography,” presented at the Proc. SPIE 13319, Photons Plus Ultrasound: Imaging and Sensing 2025, 1331905, 2025.

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  • Derivation and validation of a non-invasive optoacoustic imaging biomarker for detection of patients with intermittent claudication


    Milenko Caranovic, Julius Kempf, Yi Li, Adrian P. Regensburger, Josefine S. Günther, Anna P. Träger, Werner Lang, Alexander Meyer, Alexandra L. Wagner, Joachim Woelfle, Roman Raming, Lars-Philip Paulus, Adrian Buehler, Wolfgang Uter, Michael Uder, Christian-Alexander Behrendt, Markus F. Neurath, Maximilian J. Waldner, Ferdinand Knieling, and Ulrich Rother, “Derivation and validation of a non-invasive optoacoustic imaging biomarker for detection of patients with intermittent claudication,” Communications Medicine, vol. 5, no. 1, Art. no. 88, 2025.

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  • Optimizing image fidelity in a spherical array geometry for pulse-echo ultrasound and volumetric optoacoustic imaging


    Cheng-Feng Tommy Chiang, Isaac Esteban, Xose-Luis Dean-Ben, Jeh-Hsing Hsu, Daniel Razansky, and Hsiao-Chun Amy Lin, “Optimizing image fidelity in a spherical array geometry for pulse-echo ultrasound and volumetric optoacoustic imaging,” Photoacoustics, vol. 45, Art. no. 100754, 2025.

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  • Multispectral optoacoustic tomography enables assessment of disease activity in paediatric inflammatory bowel disease


    Adrian P. Regensburger, Markus Eckstein, Matthias Wetzl, Roman Raming, Lars-Philip Paulus, Adrian Buehler, Emmanuel Nedoschill, Vera Danko, Jörg Jüngert, Alexandra L. Wagner, Alexander Schnell, Aline Rückel, Ulrich Rother, Oliver Rompel, Michael Uder, Arndt Hartmann, Markus F. Neurath, Joachim Woelfle, Maximilian J. Waldner, André Hoerning and Ferdinand Knieling, “Multispectral optoacoustic tomography enables assessment of disease activity in paediatric inflammatory bowel disease,” Photoacoustics, vol. 35, Art. no. 100578, 2024.

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  • Teachability of multispectral optoacoustic tomography


    Yi Li, Janek Gröhl, Briain Haney, Milenko Caranovic, Eva Lorenz-Meyer, Nikolaos Papatheodorou, Julius Kempf, Adrian P. Regensburger, Emmanuel Nedoschill, Adrian Buehler, Gregor Siebenlist, Werner Lang, Michael Uder, Markus F. Neurath, Maximilian Waldner, Ferdinand Knieling and Ulrich Rother, “Teachability of multispectral optoacoustic tomography,” Journal of Biophotonics, vol. 17, no. 7, Art. no. e202400106, 2024.

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  • A Method for Accurate Spatial Focusing Simulation via Numerical Integration and its Application in Optoacoustic Tomography


    Maximilian Bader, Philipp Haim, Lukas Imanuel Scheel-Platz, Angelos Karlas, Hedwig Irl, Vasilis Ntziachristos and Dominik Jüstel, “A Method for Accurate Spatial Focusing Simulation via Numerical Integration and its Application in Optoacoustic Tomography,” eprint arXiv, 2409.10138, 2024.

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  • Spotlight on Nerves: Portable Multispectral Optoacoustic Imaging of Peripheral Nerve Vascularization and Morphology


    Dominik Jüstel, Hedwig Irl, Florian Hinterwimmer, Christoph Dehner, Walter Simson, Nassir Navab, Gerhard Schneider and Vasilis Ntziachristos, “Spotlight on Nerves: Portable Multispectral Optoacoustic Imaging of Peripheral Nerve Vascularization and Morphology,” Advanced Science, vol. 10, no. 19, Art. no. 2301322, 2023.

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  • Towards in vivo characterization of thyroid nodules suspicious for malignancy using multispectral optoacoustic tomography


    Milou E. Noltes, Maximilian Bader, Madelon J. H. Metman, Jasper Vonk, Pieter J. Steinkamp, Jan Kukačka, Henriette E. Westerlaan, Rudi A. J. O. Dierckx, Bettien M. van Hemel, Adrienne H. Brouwers, Gooitzen M. van Dam, Dominik Jüstel, Vasilis Ntziachristos and Schelto Kruijff, “Towards in vivo characterization of thyroid nodules suspicious for malignancy using multispectral optoacoustic tomography,” European Journal of Nuclear Medicine and Molecular Imaging, vol. 50, no. 9, pp. 2736–2750, 2023.

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  • Targeting Muscular Hemoglobin Content for Classification of Peripheral Arterial Disease by Noninvasive Multispectral Optoacoustic Tomography


    Josefine S. Günther, Ferdinand Knieling, Anna P. Träger, Werner Lang, Alexander Meyer, Adrian P. Regensburger, Alexandra L. Wagner, Regina Trollmann, Joachim Woelfle, Daniel Klett, Wolfgang Uter, Michael Uder, Markus F. Neurath, Maximilian J. Waldner, and Ulrich Rother, “Targeting Muscular Hemoglobin Content for Classification of Peripheral Arterial Disease by Noninvasive Multispectral Optoacoustic Tomography,” Journals of the American College of Cardiology: Cardiovascular Imaging, vol. 16, no. 5, pp. 719–721, 2023.

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  • A deep neural network for real-time optoacoustic image reconstruction with adjustable speed of sound


    Christoph Dehner, Guillaume Zahnd, Vasilis Ntziachristos, and Dominik Jüstel, “A deep neural network for real-time optoacoustic image reconstruction with adjustable speed of sound,” Nature Machine Intelligence, vol. 5, no. 10, pp. 1130–1141, 2023.

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  • Contrast-Enhanced Multispectral Optoacoustic Tomography for Functional Assessment of the Gastrointestinal Tract


    Lars-Philip Paulus, Adrian Buehler, Alexandra L. Wagner, Roman Raming, Jörg Jüngert, David Simon, Koray Tascilar, Alexander Schnell, Ulrich Rother, Markus Eckstein, Werner Lang, André Hoerning, Georg Schett, Markus F. Neurath, Maximilian J. Waldner, Regina Trollmann, Joachim Woelfle, Sarah E Bohndiek, Adrian P. Regensburger and Ferdinand Knieling, “Contrast-Enhanced Multispectral Optoacoustic Tomography for Functional Assessment of the Gastrointestinal Tract,” Advanced Science, vol. 10, no. 23, Art. no. 2302562, 2023.

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  • Hybrid reflected-ultrasound computed tomography versus B-mode-ultrasound for muscle scoring in spinal muscular atrophy


    Vera Danko, Jörg Jüngert, Stephanie Schuessler, Adrian Buehler, Daniel Klett, Anna Federle, Andreas Roos, Hanns Lochmüller, Markus F. Neurath, Joachim Woelfle, Regina Trollmann, Maximilian J. Waldner, Ferdinand Knieling, Adrian P. Regensburger and Alexandra L. Wagner, “Hybrid reflected-ultrasound computed tomography versus B-mode-ultrasound for muscle scoring in spinal muscular atrophy,” Journal of Neuroimaging, vol. 33, no. 3, pp. 393–403, 2023.

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  • Multispectral optoacoustic tomography of the human intestine – temporal precision and the influence of postprandial gastrointestinal blood flow


    Lars-Philip Paulus, Alexandra L. Wagner, Adrian Buehler, Roman Raming, Jörg Jüngert, David Simon, Koray Tascilar, Alexander Schnell, Josefine Günther, Ulrich Rother, Werner Lang, André Hoerning, Georg Schett, Markus F. Neurath, Joachim Woelfle, Maximilian J. Waldner, Ferdinand Knieling, and Adrian P. Regensburger, “Multispectral optoacoustic tomography of the human intestine – temporal precision and the influence of postprandial gastrointestinal blood flow,” Photoacoustics, vol. 30, Art. no. 100457, 2023.

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  • Derivation and validation of a non-invasive optoacoustic imaging biomarker for patients with intermittent claudication


    Milenko Caranovic, Julius Kempf, Yi Li, Adrian P. Regensburger, Josefine S. Günther, Anna P. Träger, Werner Lang, Alexander Meyer, Alexandra L. Wagner, Joachim Woelfle, Roman Raming, Lars-Philip Paulus, Adrian Buehler, Wolfgang Uter, Michael Uder, Christian-Alexander Behrendt, Markus F. Neurath, Maximilian J. Waldner, Ferdinand Knieling and Ulrich Rother, “Derivation and validation of a non-invasive optoacoustic imaging biomarker for patients with intermittent claudication,” medRxiv, 2023.

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  • Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography


    Koray Tascilar, Filippo Fagni, Arnd Kleyer, Sara Bayat, Robert Heidemann, Florian Steiger, Gerhard Krönke, Daniela Bohr, Andreas Ramming, Fabian Hartmann, Daniel Klett, Anna Federle, Adrian P Regensburger, Alexandra L Wagner, Ferdinand Knieling, Markus F Neurath, Georg Schett, Maximilian Waldner and David Simon, “Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography,” Rheumatology, vol. 62, no. 2, pp. 841–849, 2023.

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  • Optoacoustic Endoscopy of the Gastrointestinal Tract


    Hailong He, Ludwig Englert, and Vasilis Ntziachristos, “Optoacoustic Endoscopy of the Gastrointestinal Tract,” ACS Photonics, vol. 10, no. 3, pp. 559–570, 2023.

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  • Image processing improvements afford second-generation handheld optoacoustic imaging of breast cancer patients


    Jan Kukačka, Stephan Metz, Christoph Dehner, Alexander Muckenhuber, Korbinian Paul-Yuan, Angelos Karlas, Eva Maria Fallenberg, Ernst Rummeny, Dominik Jüstel and Vasilis Ntziachristos, “Image processing improvements afford second-generation handheld optoacoustic imaging of breast cancer patients,” Photoacoustics, vol. 26, Art. no. 100343, 2022.

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  • DeepMB: Deep neural network for real-time optoacoustic image reconstruction with adjustable speed of sound


    Christoph Dehner, Guillaume Zahnd, Vasilis Ntziachristos and Dominik Jüstel, “DeepMB: Deep neural network for real-time optoacoustic image reconstruction with adjustable speed of sound,” arXiv: Image and Video Processing, 27th Sep. 2022.

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  • Multispectral optoacoustic tomography for in vivo detection of lymph node metastases in oral cancer patients using an EGFR-targeted contrast agent and intrinsic tissue contrast: A proof-of-concept study


    J. Vonk, J. Kukačka, P.J. Steinkamp, J.G. de Wit, F.J. Voskuil, W.T.R. Hooghiemstra, M. Bader, D. Jüstel, V. Ntziachristos, G.M. van Dam and M.J.H. Witjes, “Multispectral optoacoustic tomography for in vivo detection of lymph node metastases in oral cancer patients using an EGFR-targeted contrast agent and intrinsic tissue contrast: A proof-of-concept study,” Photoacoustics, vol. 26, Art. no. 100362, 2022.

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  • An optoacoustic imaging feature set to characterise blood vessels surrounding benign and malignant breast lesions


    O. Abeyakoon, R. Woitek, M.G. Wallis, P.L. Moyle, S. Morscher, N. Dahlhaus, S.J. Ford, N.C. Burton, R. Manavaki, I.A. Mendichovszky, J. Joseph, I. Quiros-Gonzalez, S.E. Bohndiek F.J. Gilbert, “An optoacoustic imaging feature set to characterise blood vessels surrounding benign and malignant breast lesions,” Photoacoustics, vol. 27, Art. no. 100383, 2022.

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  • Biochemical “decoding” of breast ultrasound images with optoacoustic tomography fusion: First-in-human display of lipid and collagen signals on breast ultrasound


    Yonggeng Goh, Ghayathri Balasundaram, Hui Min Tan, Thomas Choudary Putti, Siau Wei Tang, Celene Wei Qi Ng, Shaik Ahmad Buhari, Eric Fang, Mohesh Moothanchery, Renzhe Bi, Malini Olivo and Swee Tian Quek, “Biochemical “decoding” of breast ultrasound images with optoacoustic tomography fusion: First-in-human display of lipid and collagen signals on breast ultrasound,” Photoacoustics, vol. 27, Art. no. 100377, 2022.

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  • Photoacoustic Tomography Appearance of Fat Necrosis: A First-in-Human Demonstration of Biochemical Signatures along with Histological Correlation


    Yonggeng Goh, Ghayathri Balasundaram, Hui Min Tan, Thomas Choudary Putti, Celene Wei Qi Ng, Eric Fang, Renzhe Bi, Siau Wei Tang, Shaik Ahmad Buhari, Mikael Hartman, Ching Wan Chan, Yi Ting Lim, Malini Olivo, and Swee Tian Quek, “Photoacoustic Tomography Appearance of Fat Necrosis: A First-in-Human Demonstration of Biochemical Signatures along with Histological Correlation,” Diagnostics, vol. 12, no. 10, p. 2456, 2022.

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  • Multispectral optoacoustic tomography for the non-invasive identification of patients with severe anemia in vivo


    Ingo Ganzleben, Daniel Klett, Wiebke Hartz, Lisa Götzfried, Francesco Vitali, Markus F. Neurath and Maximilian J. Waldner, “Multispectral optoacoustic tomography for the non-invasive identification of patients with severe anemia in vivo,” Photoacoustics, vol. 28, Art. no. 100414, 2022.

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  • Multispectral optoacoustic tomography for non-invasive disease phenotyping in pediatric spinal muscular atrophy patients


    Adrian P. Regensburger, Alexandra L. Wagner, Vera Danko, Jörg Jüngert, Anna Federle, Daniel Klett, Stephanie Schuessler, Adrian Buehler, Markus F. Neurath, Andreas Roos, Hanns Lochmüller, Joachim Woelfle, Regina Trollmann, Maximilian J. Waldner and Ferdinand Knieling, “Multispectral optoacoustic tomography for non-invasive disease phenotyping in pediatric spinal muscular atrophy patients,” Photoacoustics, vol. 25, Art. no. 100315, 2022.

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  • Real-time interleaved spectroscopic photoacoustic and ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction


    Geng-Shi Jeng, Meng-Lin Li, MinWoo Kim, Soon Joon Yoon, John J. Pitre Jr David S. Li, Ivan Pelivanov and Matthew O’Donnell, “Real-time interleaved spectroscopic photoacoustic and ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction,” Nature Communications, vol. 12, no. 1, Art. no. 716, 2021.

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  • Multispectral optoacoustic tomography of peripheral arterial disease based on muscle hemoglobin gradients—a pilot clinical study


    Angelos Karlas, Max Masthoff, Michael Kallmayer, Anne Helfen, Michail Bariotakis, Nikolina Alexia Fasoula, Michael Schäfers, Max Seidensticker, Hans-Henning Eckstein, Vasilis Ntziachristos and Moritz Wildgruber, “Multispectral optoacoustic tomography of peripheral arterial disease based on muscle hemoglobin gradients—a pilot clinical study,” Annals of Translational Medicine, vol. 9, no. 1, p. 36, 2021.

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  • Multicompartmental non-invasive sensing of postprandial lipemia in humans with multispectral optoacoustic tomography


    Nikolina-Alexia Fasoula, Angelos Karlas, Michael Kallmayer, Anamaria Beatrice Milik, Jaroslav Pelisek, Hans-Henning Eckstein, Martin Klingenspor, and Vasilis Ntziachristos, “Multicompartmental non-invasive sensing of postprandial lipemia in humans with multispectral optoacoustic tomography,” Molecular Metabolism, vol. 47, Art. no. 101184, 2021.

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  • Multispectral optoacoustic tomography of lipid and hemoglobin contrast in human carotid atherosclerosis


    Angelos Karlas, Michael Kallmayer, Michael Bariotakis, Nikolina-Alexia Fasoula, Evangelos Liapis, Fabien Hyafil, Jaroslav Pelisek, Moritz Wildgruber, Hans-Henning Eckstein, and Vasilis Ntziachristos, “Multispectral optoacoustic tomography of lipid and hemoglobin contrast in human carotid atherosclerosis,” Photoacoustics, vol. 23, Art. no. 100283, 2021.

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  • Clinically translatable quantitative molecular photoacoustic imaging with liposome-encapsulated ICG J-aggregates


    Cayla A. Wood, Sangheon Han, Chang Soo Kim, Yunfei Wen, Diego R. T. Sampaio, Justin T. Harris, Kimberly A. Homan, Jody L. Swain, Stanislav Y. Emelianov, Anil K. Sood, Jason R. Cook, Konstantin V. Sokolov, and Richard R. Bouchard, “Clinically translatable quantitative molecular photoacoustic imaging with liposome-encapsulated ICG J-aggregates,” Nature Communications, vol. 12, no. 1, Art. no. 5410, 2021.

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  • Photoacoustic effect of azo derivatives modified by click reagents and parceled by liposomes


    Libin Yang, Liaoliao Li, Hong Gao, Dong Wang, Zhou Yang, Hui Cao and Wanli He, “Photoacoustic effect of azo derivatives modified by click reagents and parceled by liposomes,” Dyes and Pigments, vol. 172, Art. no. 107822, 2020.

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  • Ultrasound Guided Optoacoustic Tomography in Assessment of Tumor Margins for Lumpectomies


    Yonggeng Goh, Ghayathri Balasundaram, Mohesh Moothanchery, Amalina Attia, Xiuting Li, Hann Qian Lim, Neal C. Burton, Yi Qiu, Thomas Choudary Putti, Ching Wan Chan, Philip Iau, Shaik Ahmad Buhari, Mikael Hartman, Siau Wei Tang, Celene Wei Qi Ng, Yiong Huak Chan, Felicity Jane Pool, Premilla Pillay, Wynne Chua, Jeevesh Kapur, Pooja Jagmohan, Eide Sterling, Swee Tian Quek and Malini Olivo, “Ultrasound Guided Optoacoustic Tomography in Assessment of Tumor Margins for Lumpectomies,” Translational Oncology, vol. 13, no. 2, pp. 254–261, 2020.

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  • Deep Learning for Automatic Segmentation of Hybrid Optoacoustic Ultrasound (OPUS) Images


    Berkan Lafci, Elena Merčep, Stefan Morscher, Xosé Luís Deán-Ben and Daniel Razansky, “Deep Learning for Automatic Segmentation of Hybrid Optoacoustic Ultrasound (OPUS) Images,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 68, no. 3, pp. 688–696, 2020.

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  • Optoacoustic characterization of breast conserving surgery specimens–A pilot study


    Ghayathri Balasundaram, Yonggeng Goh, Mohesh Moothanchery, Amalina Attia, Hann Qian Lim, Neal C. Burton, Yi Qiu, Thomas Choudary Putti, Ching Wan Chan, Mikael Hartmann, Swee Tian Quek and Malini Olivo, “Optoacoustic characterization of breast conserving surgery specimens–A pilot study,” Photoacoustics, vol. 19, Art. no. 100164, 2020.

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  • Bedside 3D Visualization of Lymphatic Vessels with a Handheld Multispectral Optoacoustic Tomography Device


    Guido Giacalone, Takumi Yamamoto, Florence Belva, and Akitatsu Hayashi, “Bedside 3D Visualization of Lymphatic Vessels with a Handheld Multispectral Optoacoustic Tomography Device,” Journal of Clinical Medicine, vol. 9, no. 3, p. 815, 2020.

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  • Efficient segmentation of multi-modal optoacoustic and ultrasound images using convolutional neural networks


    Berkan Lafci, Elena Merćep, Stefan Morscher, Xosé Luís Deán-Ben, and Daniel Razansky, “Efficient segmentation of multi-modal optoacoustic and ultrasound images using convolutional neural networks,” presented at the SPIE BiOS, San Francisco, California, United States, 2020.

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  • Visualizing Alzheimer’s Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7


    Sung-Jin Park, Chris Jun Hui Ho, Satoshi Arai, Animesh Samanta, Malini Olivo, and Young-Tae Chang, “Visualizing Alzheimer’s Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7,” Scientific Reports, vol. 9, no. 1, Art. no. 12052, 2019.

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  • Assessment of Nonradioactive Multispectral Optoacoustic Tomographic Imaging With Conventional Lymphoscintigraphic Imaging for Sentinel Lymph Node Biopsy in Melanoma


    Ingo Stoffels, Philipp Jansen, Maximilian Petri, Lukas Goerdt,Titus J. Brinker, Klaus G. Griewank, Thorsten D. Poeppel, Dirk Schadendorf and Joachim Klode, “Assessment of Nonradioactive Multispectral Optoacoustic Tomographic Imaging With Conventional Lymphoscintigraphic Imaging for Sentinel Lymph Node Biopsy in Melanoma,” JAMA Network Open, vol. 2, no. 8, p. e199020, 2019.

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  • Transmission–reflection optoacoustic ultrasound (TROPUS) computed tomography of small animals


    Elena Merčep, Joaquín L. Herraiz, Xosé Luís Deán-Ben and Daniel Razansky, “Transmission–reflection optoacoustic ultrasound (TROPUS) computed tomography of small animals,” Nature Light: Science & Applications, vol. 8, no. 1, Art. no. 18, 2019.

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  • Multispectral optoacoustic tomography of benign and malignant thyroid disorders-a pilot study


    Wolfgang Roll, Niklas A. Markwardt, Max Masthoff, Anne Helfen, Jing Claussen, Michel Eisenblätter, Alexa Hasenbach, Sven Hermann, Angelos Karlas, Moritz Wildgruber, Vasilis Ntziachristos and Michael Schäfers, “Multispectral optoacoustic tomography of benign and malignant thyroid disorders-a pilot study,” Journal of Nuclear Medicine, vol. 60, no. 10, pp. 1461–1466, 2019.

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  • Multispectral Optoacoustic Tomography: Intra- and Interobserver Variability Using a Clinical Hybrid Approach


    Anne Helfen, Max Masthoff, Jing Claussen, Mirjam Gerwing, Walter Heindel, Vasilis Ntziachristos, Michel Eisenblätter, Michael Köhler and Moritz Wildgruber, “Multispectral Optoacoustic Tomography: Intra- and Interobserver Variability Using a Clinical Hybrid Approach,” Journal of Clinical Medicine, vol. 8, no. 1, p. 63, 2019.

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  • Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy


    Adrian P. Regensburger, Lina M. Fonteyne, Jörg Jüngert, Alexandra L. Wagner, Teresa Gerhalter, Armin M. Nagel, Rafael Heiss, Florian Flenkenthaler, Matthias Qurashi, Markus F. Neurath, Nikolai Klymiuk, Elisabeth Kemter, Thomas Fröhlich, Michael Uder, Joachim Woelfle, Wolfgang Rascher, Regina Trollmann, Eckhard Wolf, Maximilian J. Waldner and Ferdinand Knieling, “Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy,” Nature Medicine, vol. 25, no. 12, pp. 1905–1915, 2019.

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  • Functionalised iron oxide nanoparticles for multimodal optoacoustic and magnetic resonance imaging


    Gavin Bell, Ghayathri Balasundaram, Amalina Binte Ebrahim Attia, Francesca Mandino, Malini Olivo and Ivan P. Parkin, “Functionalised iron oxide nanoparticles for multimodal optoacoustic and magnetic resonance imaging,” Journal of Materials Chemistry B, vol. 7, no. 13, pp. 2212–2219, 2019.

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  • Multispectral Optoacoustic Tomography in Assessment of Breast Tumor Margins During Breast-Conserving Surgery: A First-in-human Case Study


    Yonggeng Goh, Ghayathri Balasundaram, Mohesh Moothanchery, Amalina Attia, Xiuting Li, Hann Qian Lim, Neal Burton, Yi Qiu, Thomas Choudary Putti, Ching Wan Chan, Philip Iau, Siau Wei Tang, Celene Wei Qi Ng, Felicity Jane Pool, Premilla Pillay, Wynne Chua, Eide Sterling, Swee Tian Quek, Malini Olivo, “Multispectral Optoacoustic Tomography in Assessment of Breast Tumor Margins During Breast-Conserving Surgery: A First-in-human Case Study.,” Clinical Breast Cancer, vol. 18, no. 6, pp. e1247–e1250, 2018.

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  • Multimodal Imaging Approach to Monitor Browning of Adipose Tissue In Vivo


    Xin Hui Derryn Chan, Ghayathri Balasundaram2, Amalina Binte Ebrahim Attia, Julian L. Goggi, Boominathan Ramasamy, Weiping Han, Malini Olivo, Shigeki Sugii, “Multimodal Imaging Approach to Monitor Browning of Adipose Tissue In Vivo.,” Journal of Lipid Research, vol. 59, no. 6, pp. 1071–1078, 2018.

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  • Small Molecule Optoacoustic Contrast Agents: An Unexplored Avenue for Enhancing In Vivo Imaging


    Matt D. Laramie, Mary K. Smith, Fahad Marmarchi, Lacey R. McNally, and Maged Henary, “Small Molecule Optoacoustic Contrast Agents: An Unexplored Avenue for Enhancing In Vivo Imaging.,” Molecules, vol. 23, no. 11, p. 2766, 2018.

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  • Imaging of blood flow and oxygen state with a multi-segment optoacoustic ultrasound array


    Elena Merčep, Xosé Luís, Deán-Ben, and Daniel Razansky, “Imaging of blood flow and oxygen state with a multi-segment optoacoustic ultrasound array.,” Photoacoustics, vol. 10, pp. 48–53, 2018.

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  • Optoacoustic Imaging Detects Hormone-Related Physiological Changes of Breast Parenchyma


    Oshaani Abeyakoon, Stefan Morscher, Nina Dalhaus, Steven J. Ford, Iosif A. Mendichovszky, Roido Manavaki, Matthew Wallis, Penelope Moyle, Ramona Woitek, Andrew Patterson, Turid Torheim, James Joseph, Isabel Quiros Gonzalez, Sarah Bohndiek, Fiona J. Gilbert, “Optoacoustic Imaging Detects Hormone-Related Physiological Changes of Breast Parenchyma.,” Ultraschall in Med, vol. 40, no. 06, pp. 757–763, 2018.

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  • Multispectral optoacoustic tomography of systemic sclerosis


    Max Masthoff, Anne Helfen1, Jing Claussen, Wolfgang Roll, Angelos Karlas, Heidemarie Becker, Gert Gabriëls, Jan Riess, Walter Heindel, Michael Schäfers, Vasilis Ntziachristos, Michel Eisenblätter, Ulrich Gerth and Moritz Wildgruber, “Multispectral optoacoustic tomography of systemic sclerosis.,” Journal of biophotonics, vol. 11, no. 11, Art. no. e201800155, 2018.

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  • Use of Multispectral Optoacoustic Tomography to Diagnose Vascular Malformations


    Max Masthoff, Anne Helfen, Jing Claussen, Angelos Karlas, Niklas A. Markwardt, Vasilis Ntziachristos, Michel Eisenblätter, and Moritz Wildgruber, “Use of Multispectral Optoacoustic Tomography to Diagnose Vascular Malformations.,” JAMA Dermatology, vol. 154, no. 12, p. 1457, 2018.

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  • Hybrid-array-based optoacoustic and ultrasound (OPUS) imaging of biological tissues


    X. L. Deán-Ben, E. Merčep, and D. Razansky, “Hybrid-array-based optoacoustic and ultrasound (OPUS) imaging of biological tissues.,” Applied Physics Letters, vol. 110, no. 20, Art. no. 203703, 2017.

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  • Multispectral optoacoustic tomography of the human breast: characterisation of healthy tissue and malignant lesions using a hybrid ultrasound-optoacoustic approach


    Anne Becker, Max Masthoff, Jing Claussen, Steven James Ford, Wolfgang Roll, Matthias Burg, Peter J. Barth, Walter Heindel, Michael Schäfers, Michel Eisenblätter, Moritz Wildgruber, “Multispectral optoacoustic tomography of the human breast: characterisation of healthy tissue and malignant lesions using a hybrid ultrasound-optoacoustic approach.,” European Society of Radiology, vol. 28, no. 2, pp. 602–609, 2017.

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