Prospect

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Estimating the delivery efficiency of drug-loaded Microbubbles in cancer cells with ultrasound and bioluminescence imaging

Ai-Ho Liao, Ying-Kai Li, Wei-Jiunn Lee, Ming-Fang Wu, Hao-Li Liu, Min-Liang Kuo, “Estimating the delivery efficiency of drug-loaded Microbubbles in cancer cells with ultrasound and bioluminescence imaging”, Ultrasound in Medicine and Biology, 38(11), 1938-48, 2012.

Dynamic observation on rabbit ear hypertrophic scar formation with high frequency ultrasound biomicroscopy

Y.-F. You, Z.-G. Wang, Y.-Y. Zheng, W.-Y. Li and C.-C. Niu, “Dynamic observation on rabbit ear hypertrophic scar formation with high frequency ultrasound biomicroscopy”, Chinese Journal of Medical Imaging Technology, 28(12), P. 2122-2126, 2012. (In Chinese)

Investigation on anisotropy of elastic properties in tendon using shear wave elasticity imaging

Chia-Lun Yeh, Yae-Lin Sheu, Po-Ling Kuo, Pai-Chi Li, “Investigation on anisotropy of elastic properties in tendon using shear wave elasticity imaging”, IEEE International Ultrasonics Symposium(IUS), Dresden, Germany, October 7-10, 2012.

Enhanced delivery of gold nanoparticles by acoustic cavitation for photoacoustic imaging and photothermal therapy

Y.-H. Wang, A.-H. Liao, J.-Y. Lin, C.-R. Lee, C.-H. Wu, T.-M. Liu, C.-R. Chris Wang and P.-C. Li, “Enhanced delivery of gold nanoparticles by acoustic cavitation for photoacoustic imaging and photothermal therapy”, SPIE Photonic West 2013, San Francisco, California, February 2-7, 2013.

Using Prospect high resolution imaging system to monitor cardiac function in post myocardial infarct mice treated with or without a TGFβ inhibitor

Wen-Pin Chen, Lung-Chun Lin, Pai-Chi Li, “Using Prospect high resolution imaging system to monitor cardiac function in post myocardial infarct mice treated with or without a TGFβ inhibitor ”, WFUMB 2013, Sao Paulo, Brazil, May 2-5, 2013.

To investigate the progression of myocardial infarction by echocardiographic assessment

Bo-Jhih Pan, Ming-Sian Jiang, Chan-Jung Liang, Wen-Ping Chen, Pai-Chi Li and Yuh-Lien Chen, “To investigate the progression of myocardial infarction by echocardiographic assessment”, WFUMB 2013, Sao Paulo, Brazil, May 2-5, 2013.

Complementary coded excitation for improvement of Doppler sensitivity in pre-clinical ultrasound imaging system.

Che-Chou Shen, Gency Jeng, “Complementary coded excitation for improvement of Doppler sensitivity in pre-clinical ultrasound imaging system.” EMIM 2013, Torino, Italy, May 26-28, 2013.

The study of absorption efficiency of microbubbles combines with ultrasound on skin treatment.

Ai-Ho Liao, Wan-Chun Ma, “The study of absorption efficiency of microbubbles combines with ultrasound on skin treatment.” WMIC 2013, Savannah, Georgia, September 18-21, 2013.

A novel use of chitosan combines with ultrasound for body weight and local fat controlled in Mice

Ai-Ho Liao, Wan-Chun Ma, “A novel use of chitosan combines with ultrasound for body weight and local fat controlled in Mice”, WMIC 2013, Savannah, Georgia, September 18-21, 2013.

Ischemic postconditioning–mediated miRAN-21 protests against cardiac ischemia/reperfusion injury via PTEN/Akt Pathway

Y. Tu, L. Wan, Y. Fan, K. Wang, L. Bu, T. Hung, Z. Cheng, “Ischemic postconditioning–mediated miRAN-21 protests against cardiac ischemia/reperfusion injury via PTEN/Akt Pathway”, PlOS ONE, 10(8), P.18-21, 2013.

In vivo measurement of liver elasticity on mice using a single element preclinical ultrasound system

Chia-Lun Yeh, Bo-Rong Chen, Po-Ling Kuo, and Pai-Chi Li, “In vivo measurement of liver elasticity on mice using a single element preclinical ultrasound system”, ICBMU 2013, Taipei, Taiwan, October 22-23, 2013.

Evaluation of Ultrasound Combined with Chitosan for Control of Weight and Local Fat in Mice

Ai-Ho Liao, Wan-Chun Ma, Ming-Fang Wu, “Evaluation of Ultrasound Combined with Chitosan for Control of Weight and Local Fat in Mice”, Ultrasound in Medicine & Biology, 39(10), P.1794-1803, 2013.

Non-invasive tissue elastography for measurement of liver fibrosis in mice, a pilot study

Tung-Hung Su, Nien-Ching Ho, Ping Jao, Ling-Yi Tseng, Jia-Horng Kao, Pei-Jer Chen, Kuen-Feng Chen, Pai-Chi Li, Shiou-Hwei Yeh, “Non-invasive tissue elastography for measurement of liver fibrosis in mice, a pilot study”, APASL 2014, Brisbane, Australia, March 12-15, 2014.

Paramagnetic hollow silica nanospheres for in vivo targeted ultrasound and magnetic resonance imaging

Lu An, He Hu, Jing Du, Jie Wei, Li Wang, Hong Yang, Dongmei Wu, Haili Shi, Fenghua Li, Shiping Yang, “Paramagnetic hollow silica nanospheres for in vivo targeted ultrasound and magnetic resonance imaging ”, Biomaterials, 3^rdApril, 2014.

Prostate stem cell antigen antibody-conjugated multiwalled carbon nanotubes for targeted ultrasound imaging and drug delivery

Huixia Wu, Haili Shi, Hao Zhang, Xue Wang, Yan Yang, Chao Yu, Caiqin Hao, Jing Du, He Hu, Shiping Yang, “Prostate stem cell antigen antibody-conjugated multiwalled carbon nanotubes for targeted ultrasound imaging and drug delivery ”, Biomaterials, 5^th April, 2014.

Synergistic delivery of gold nanorods using multifunctional microbubbles for enhanced plasmonic photothermal therapy.

Yu-Hsin Wang, Shi-Ping Chen, Ai-Ho Liao, Ya-Chuen Yang, Cheng-Ru Lee, Cheng-Han Wu, Pei-Chun Wu, Tzu-Ming Liu, Churng-Ren Chris Wang, Pai-Chi Li, “Synergistic delivery of gold nanorods using multifunctional microbubbles for enhanced plasmonic photothermal therapy.” Scientific Rep., 4, 5685(2014)

3D cell mechanobiology study using shear wave elasticity imaging

Chun-Ting Li, Chin-Hsiung Tsai, Pai-Chi Li, Po-Ling Kuo, “3D cell mechanobiology study using shear wave elasticity imaging”, IEEE International Ultrasonics Symposium (IUS), Chicago Illinois, USA, September 3-6, 2014.

Shear wave elastography of a liver fibrosis mouse model using a high frequency ultrasound system with mechanical scanning

Chia-Lun Yeh, Bo-Rong Chen, Ling-Yi Tseng, Ping Jao, Tung-Hung Su, Pai-Chi Li, “Shear wave elastography of a liver fibrosis mouse model using a high frequency ultrasound system with mechanical scanning”, IEEE International Ultrasonics Symposium (IUS), Chicago Illinois, USA, September 3-6, 2014.

Declined Cardiac Function causes Aerobic Exercise Impairment in the R6/2 Mice of Huntington’s Disease

Tai-Yuan Chuang, Chia-Ying Lien, Mei-Li Chen, Brock T. Jensen, Ding-Siang Huang, Sheue-Er Wang, Chih-hsiang Hsu, Chuang Hsing Huang, Wu Chung-Hsin, “Declined Cardiac Function causes Aerobic Exercise Impairment in the R6/2 Mice of Huntington’s Disease”, WMIC 2014, Soul, Korea, September 17-20, 2014.

The Effect of Medical Herbs (Danshen and Panax Ginseng) Combination on Doxorubicin-Induced Cardiotoxicity

Tai-Yuan Chuang, Brock T. Jensen, Mei-Li Chen, Wu Chung-Hsin, Chia-Ying Lien, “The Effect of Medical Herbs (Danshen and Panax Ginseng) Combination on Doxorubicin-Induced Cardiotoxicity”, WMIC 2014, Soul, Korea, September 17-20, 2014.

Assessment of Whole Body Fat Composition in Mice using 3D Local Fat Pad Ultrasound Imaging

Ai-Ho Liao, Chun-Chieh Li, Ho-Chiao Chuang, “Assessment of Whole Body Fat Composition in Mice using 3D Local Fat Pad Ultrasound Imaging”, WMIC 2014, Soul, Korea, September 17-20, 2014.

Combined therapeutic ultrasound with the microbubbles to enhance anti-inflammatory drug delivery in arthritis rat

Huan-Yu Zhung, Ming-Kung Yeh, Ai-Ho Liao, “Combined therapeutic ultrasound with the microbubbles to enhance anti-inflammatory drug delivery in arthritis rat”, WMIC 2014, Soul, Korea, September 17-20, 2014.

Evans Blue Extravasation in Mouse Tumor Model Using Ultrasound Image-Guided Sonoporation

Ling-Yi Tseng, Yu-Ren Liou, Chung-Hsin Wang, Da-Liang Ou, Pai-Chi Li, “Evans Blue Extravasation in Mouse Tumor Model Using Ultrasound Image-Guided Sonoporation ”, WMIC 2014, Soul, Korea, September 17-20, 2014.

Cardiac fibroblasts: contributory role in septic cardiac dysfunction

Kengo Tomita, Mitchinori Takashina, Natsumi Mizuno, Kimimasa Sakata, Kohshi Hattori, Joji Imura, MD, Wakana Ohashi, Yuichi Hattori, “Cardiac fibroblasts: contributory role in septic cardiac dysfunction”, Journal of Surgical Research, 193(2), P. 874–887, 2015.

Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis

Chia-Ying Lien, Tai-Yuan Chuang, Chih-Hsiang Hsu, Ching-Lung Lin, Sheue-Er Wang, Shuenn-Jyi Sheu, Chiang-Ting Chien, and Chung-Hsin Wu, “Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis”, OncoTargets Therapy, 8, p.1193-1210, 2015.

TGFβRI Inhibition Produces Dual Cardioprotective Actions through Increasing Survivin and Inhibiting Wnt Expressions in Cardiac Progenitors

Yu-Sian Ho, Fen-Chiung Lin, Wan-Hsuan Tsai, Wen-Pin Chen, “TGFβRI Inhibition Produces Dual Cardioprotective Actions through Increasing Survivin and Inhibiting Wnt Expressions in Cardiac Progenitors”, WMIC 2015, Honolulu Hawaii, USA, September 2-5, 2015.

DNase1 Decrease the Formation of the Size of Vegetation in Experimental Endocarditis Rat Model

Jeng-Wei Chen, Ling-Yi Tseng, Jean-San Chia, “DNase1 Decrease the Formation of the Size of Vegetation in Experimental Endocarditis Rat Model”, WMIC 2015, Honolulu Hawaii, USA, September 2-5, 2015.

The effect of moderate endurance exercise during doxorubicin-treatment in tumor-bearing mice

Tai-Yuan Chuang, Brock T. Jensen, Mei-Li Chen, Hu Cheng, Chia-Ying Lien, “The effect of moderate endurance exercise during doxorubicin-treatment in tumor-bearing mice”, WMIC 2015, Honolulu Hawaii, USA, September 2-5, 2015.

Feasibility study of the hair growth enhancements with ultrasound-mediated minoxidil loaded microbubbles cavitation

Ai-Ho Liao, Ying-Jui Lu, “Feasibility study of the hair growth enhancements with ultrasound-mediated minoxidil loaded microbubbles cavitation”, WMIC 2015, Honolulu Hawaii, USA, September 2-5, 2015.

Evaluating elasticity dynamics of three-dimensional cell-matrix using ultrasonic shear waves

Po-Ling Kuo, Pai-Chi Li, “Evaluating elasticity dynamics of three-dimensional cell-matrix using ultrasonic shear waves”, 8th AP Biomechanics, September 16-19, 2015.

Implementation and evaluation of slow-time Golay decoding for pre-clinical high-frequency color Doppler imaging in mice

Che-Chou Shen, Jyun-Gong Yu, Gency Jeng, “Implementation and evaluation of slow-time Golay decoding for pre-clinical high-frequency color Doppler imaging in mice”, IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, October 21-24, 2015.

Near Field Shear Wave Elasticity Imaging with High Frequency Single Element Transducers

Nien-Ching Ho and Pai-Chi Li, “Near Field Shear Wave Elasticity Imaging with High Frequency Single Element Transducers”, IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, October 21-24, 2015.

Evaluation the potential of the hair growth enhancements with ultrasound-mediated minoxidil loaded microbubbles cavitation

Ai-Ho Liao, Ying-Jui Lu, “Evaluation the potential of the hair growth enhancements with ultrasound-mediated minoxidil loaded microbubbles cavitation”, IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, October 21-24, 2015.

Efficacy of ultrasound mediated microbubbles in diclofenac gel to enhance transdermal permeation in rheumatoid arthritis induced rat

A.H. Liao, H.C. Chuang, H.Y. Chung, “Efficacy of ultrasound mediated microbubbles in diclofenac gel to enhance transdermal permeation in rheumatoid arthritis induced rat”, IEEE Engineering in Medicine and Biology Society (EMBC), Milan, Italy, Aug. 25-29, 2015.

Anti-Inflammatory Profile of Levosimendan in Cecal Ligation-Induced Septic Mice and in Lipopolysaccharide-Stimulated Macrophages

Qiang Wang, Hiroki Yokoo, Michinori Takashina, Kimimasa Sakata, Wakana Ohashi, Lobna A. Abedelzaher, Takahiro Imaizumi, Takuya Sakamoto, Kohshi Hattori, Naoyuki Matsuda, Yuichi Hattori, “Anti-Inflammatory Profile of Levosimendan in Cecal Ligation-Induced Septic Mice and in Lipopolysaccharide-Stimulated Macrophages”, Critical Care Medicine, 43(11), e508-520, 2015.

Preparation of pH-responsive hollow poly(MAA-co-EGDMA) nanocapsules for drug delivery and ultrasound imaging

He Hu, Xiaofen Zhang, Jin Sun, Lu An, Jing Du, Hong Yang, Fenghua Li, Huixia Wua and Shiping Yang, “Preparation of pH-responsive hollow poly(MAA-co-EGDMA) nanocapsules for drug delivery and ultrasound imaging”, Royal Society of Chemistry Advances, 6(105), P.103754-103762, 2016.

Acoustic and optical droplet vaporization for enhanced sonoporation

Wei-Wen Liu, Chi-Ting Wu, Churng-Ren Chris Wang, Pai-Chi Li, “Acoustic and optical droplet vaporization for enhanced sonoporation”, IEEE International Ultrasonics Symposium (IUS), Tours, France, Sept. 18-21, 2016.

Efficacy of Combined Ultrasound-and-Microbubbles-Mediated Diclofenac Gel Delivery to Enhance Transdermal Permeation in Adjuvant-Induced Rheumatoid Arthritis in the Rat

Ai-Ho Liao, Huan-Yu Chung, Wen-Shiang Chen, Ming-Kung Yeh, “Efficacy of Combined Ultrasound-and-Microbubbles-Mediated Diclofenac Gel Delivery to Enhance Transdermal Permeation in Adjuvant-Induced Rheumatoid Arthritis in the Rat”, Ultrasound in Medical and Biology, 42(8), P.1976-1985, 2016.

Nanodroplet-Vaporization-Assisted Sonoporation for Highly Effective Delivery of Photothermal Treatment

Wei-Wen Liu, Shu-Wei Liu, Yu-Ren Liou, Yu-Hsun Wu, Ya-Chuen Yang, Churng-Ren Chris Wang, and Pai-Chi Li, “Nanodroplet-Vaporization-Assisted Sonoporation for Highly Effective Delivery of Photothermal Treatment”, Scientific Report, 6(24753), 2016.

Efficacy of transdermal magnesium ascorbyl phosphate delivery after ultrasound treatment with microbubbles in gel-type surrounding medium in mice

Ai-Ho Liao, Ying-Jui Lu, Chi-Ray Hung, Meng-Yu Yang, “Efficacy of transdermal magnesium ascorbyl phosphate delivery after ultrasound treatment with microbubbles in gel-type surrounding medium in mice”, Materials Science and Engineering: C on ScienceDirect, 61(1), P.591-598, 2016.

Shear-Wave Measurements for Evaluation of Tendon Diseases

C.L. Yeh, P.L. Kuo, J. L. Gennisson, J. Brum, M. Tanter and P.C. Li, “Shear-Wave Measurements for Evaluation of Tendon Diseases”, IEEE transactions on ultrasonics, ferroelectrics and frequency control, 63(11), P.1906-1921, 2016.

Evaluation of the wound healing enhancements with ultrasound-mediated epidermal growth factor loaded lysozyme shelled microbubbles

Ai-Ho Liao, Chi-Ruei Hong, “Evaluation of the wound healing enhancements with ultrasound-mediated epidermal growth factor loaded lysozyme shelled microbubbles”, WMIC 2016, New York, New York, America, 2016.

Evaluation of the enhancements with ultrasound-mediated retinoid loaded microbubbles on photoaging

Ai-Ho Liao, You-Lin Cia, “Evaluation of the enhancements with ultrasound-mediated retinoid loaded microbubbles on photoaging”, WMIC 2016, New York, New York, America, 2016.

Using high-frequency ultrasound statistical scattering model to assess Nonalcoholic Fatty Liver Disease (NAFLD) in mice

Che-Chou Shen, Sheng-Chang Yu, and Chia-Yuan Liu, “Using high-frequency ultrasound statistical scattering model to assess Nonalcoholic Fatty Liver Disease (NAFLD) in mice”, Telecommunications and Signal Processing (TSP), Vienna, Austria, 2016.

Shear-wave elasticity measurements of three-dimensional cell cultures for mechanobiology

Po-Ling Kuo, Chin-Che Charng, Po-Chen Wu, Pai-Chi Li, “Shear-wave elasticity measurements of three-dimensional cell cultures for mechanobiology”, Journal of Cell Science, 130(1), P.292-302, 2017.

Diminished Responsiveness to Dobutamine as an Inotrope in Mice with Cecal Ligation and Puncture-Induced Sepsis: Attribution to Phosphodiesterase 4 Upregulation

Sakai M, Suzuki T, Tomita K, Yamashita S, Palikhe S, Hattori K, Yoshimura N, Matsuda N and Hattori Y., “Diminished Responsiveness to Dobutamine as an Inotrope in Mice with Cecal Ligation and Puncture-Induced Sepsis: Attribution to Phosphodiesterase 4 Upregulation”, American Journal of Physiology-Heart and Circulatory Physiology, 2017 Apr 28.

Synergistic inhibitory effects on hepatocellular carcinoma with recombinant human adenovirus Aspp2 and oxaliplatin via p53-independent pathway in vitro and in vivo

Xiaoni Liu, Jianji Xu, Shuang Wang, Xiaoxiao Yu, Boxin Kou, Mengyin Chai, Yunjin Zang and Dexi Chen, “Synergistic inhibitory effects on hepatocellular carcinoma with recombinant human adenovirus Aspp2 and oxaliplatin via p53-independent pathway in vitro and in vivo”, International Journal of Oncology, 51(4), P.1291-1299, 2017.

Exosomes Derived From Natural Killer Cells Exert Therapeutic Effect in Melanoma

Liya Zhu, Senthilkumar Kalimuthu, Prakash Gangadaran, Ji-Min Oh, Ho-Won Lee, Se-Hwan Baek, Shin-Young Jeong, Sang-Woo Lee, Jaetae Lee, and Byeong-Cheol Ahn, “Exosomes Derived From Natural Killer Cells Exert Therapeutic Effect in Melanoma”, Theranostics, 7(10), P. 2732-2745, 2017.

Aliskiren Improves Ischemia- and Oxygen Glucose Deprivation-Induced Cardiac Injury through Activation of Autophagy and AMP-Activated Protein Kinase

Ming-Hsien Chiang, Chan-Jung Liang, Chen-Wei Liu, Bo-Jhih Pan, Wen-Ping Chen, Yi-Fan Yang, I-Ta Lee, Jaw-Shiun Tsai, Chiang-Wen Lee and Yuh-Lien Chen, “Aliskiren Improves Ischemia- and Oxygen Glucose Deprivation-Induced Cardiac Injury through Activation of Autophagy and AMP-Activated Protein Kinase”, Frontiers in Pharmacology, 8:819, 2017.

Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genes

Joan Comenge, Jack Sharkey, Oihane Fragueiro, Bettina Wilm, Mathias Brust, Patricia Murray, Raphael Levy and Antonius Plagge, “Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genes”, bioRxiv, 2017.

Oral administration of Ginsenoside Rg1 prevents cardiac toxicity induced by doxorubicin in mice through anti-apoptosis

Chen Zhu, Yi Wang, Hua Liu, Haiman Mu, Yue Lu, Jiayi Zhang, and Jianhua Huang, “Oral administration of Ginsenoside Rg1 prevents cardiac toxicity induced by doxorubicin in mice through anti-apoptosis”, Oncotarget, 8(48), P. 83792-83801, 2017.

SNR improvement and range side lobe suppression in Golay-encoded Doppler detection for ultrasound high-frequency swept-scan imaging system

Jyun-Gong Yu, Pin-Hsian Liu, Che-Chou Shen, “SNR improvement and range side lobe suppression in Golay-encoded Doppler detection for ultrasound high-frequency swept-scan imaging system”, Biomedical Signal Processing and Control, 41, P. 31-39, 2018.

Preparation and imaging investigation of dual-targeted C3F8-filled PLGA nanobubbles as a Novel ultrasound Contrast agent for breast cancer

Jing Du, Xiao-Yu Li, He Hu, Li Xu, Shi-Ping Yang and Feng-Hua Li, “Preparation and imaging investigation of dual-targeted C3F8-filled PLGA nanobubbles as a Novel ultrasound Contrast agent for breast cancer”, Scientific Reports, 8(3887), 2018.

Exploration of antigen induced CaCO3 Nanoparticles for therapeutic vaccine

Shuang Wang, Dezhi Ni, Hua Yue, Nana Luo, Xiaobo Xi, Yugang Wang, Min Shi, Wei Wei and Guanghui Ma, “Exploration of antigen induced CaCO3 Nanoparticles for therapeutic vaccine”, smallNaNO MICRO, Feb 22, 2018.

Development of a PD-L1-Expressing Orthotopic Liver Cancer Model: Implications for Immunotherapy for Hepatocellular Carcinoma

Ou D.-L., Lin Y.-Y., Hsu C.-L., Lin Y.-Y., Chen C.-W., Yu J.-S., Miaw S.-C., Hsu P.-N., Cheng A.-L., and Hsu C, “Development of a PD-L1-Expressing Orthotopic Liver Cancer Model: Implications for Immunotherapy for Hepatocellular Carcinoma”, Liver Cancer, Published online: June 22, 2018.

Cardioprotective and functional effects of levosimendan and milrinone in mice with cecal ligation and puncture-induced sepsis

Shigeyuki Yamashita, Tokiko Suzuki, Keisuke Iguchi, Takuya Sakamoto, Kengo Tomita, Hiroki Yokoo, Mari Sakai, Hiroki Misawa, Kohshi Hattori, Toshi Nagata, Yasuhide Watanabe, Naoyuki Matsuda, Naoki Yoshimura, and Yuichi Hattori, “Cardioprotective and functional effects of levosimendan and milrinone in mice with cecal ligation and puncture-induced sepsis”, Naunyn-Schmiedeberg's Archives of Pharmacology, 391(9), P.1021–1032, 2018.

Ultrasound molecular imaging of breast cancer in MCF-7 orthotopic mice using gold nanoshelled poly(lactic-co-glycolic acid) nanocapsules: a novel dual-targeted ultrasound contrast agent

Li Xu, Jing Du, Caifeng Wan, Yu Zhang, Shaowei Xie, Hongli Li, Hong Yang, and Fenghua Li, “Ultrasound molecular imaging of breast cancer in MCF-7 orthotopic mice using gold nanoshelled poly(lactic-co-glycolic acid) nanocapsules: a novel dual-targeted ultrasound contrast agent”, National Institutes of Health, 13, P.1791–1807, 2018.

Surface-engineered nanobubbles with pH-/light-responsive drug release and charge-switchable behaviors for active NIR/MR/US imaging-guided tumor therapy

Tianliang Li, Jia Zhou, Chunlei Zhang, Xiao Zhi, Jiaqi Niu, Hualin Fu, Jie Song and Daxiang Cui, “Surface-engineered nanobubbles with pH-/light-responsive drug release and charge-switchable behaviors for active NIR/MR/US imaging-guided tumor therapy”, NPG Asia Materials, Published on 7th November 2018.

Ultrasound-Mediated EGF-Coated-Microbubble Cavitation in Dressings for Wound-Healing Applications

Ai-Ho Liao, Chi-Ray Hung, Hang-Kang Chen and Chien-Ping Chiang, “Ultrasound-Mediated EGF-Coated-Microbubble Cavitation in Dressings for Wound-Healing Applications”, Scientific Reports, 8(8327), 2018.

Insulin-like growth factor binding protein related protein 1 knockdown attenuates hepatic fibrosis via the regulation of MMPs/TIMPs in mice

Ren Jun-Jiea, Huang Ting-Juana, Zhang Qian-Qiana, Zhang Hai-Yana, Guo Xiao-Hong, Fan Hui-Qin, Li Ren-Ke, Liu Li-Xin, “Insulin-like growth factor binding protein related protein 1 knockdown attenuates hepatic fibrosis via the regulation of MMPs/TIMPs in mice”, Hepatobiliary & Pancreatic Diseases International, Available online 29 August 2018.

Development of an imaging toolbox to assess the therapeutic potential and biodistribution of macrophages in a mouse model of multiple organ dysfunction

Jack Sharkey, Lorenzo Ressel, Nathalie Brillant, Bettina Wilm, Kevin Park, and Patricia Murray, “Development of an imaging toolbox to assess the therapeutic potential and biodistribution of macrophages in a mouse model of multiple organ dysfunction”, bioRxiv, Posted online Jul. 19, 2018.

Real-time observation of pathophysiological processes during murine experimental Schistosoma japonicum infection using high-resolution ultrasound imaging

Katsumi Maezawa, Rieko Furushima-Shimogawara, Akio Yasukawa, Nobuo Ohta and Shiro Iwanaga, “Real-time observation of pathophysiological processes during murine experimental Schistosoma japonicum infection using high-resolution ultrasound imaging”, Tropical Medicine and Health, Published: 10 December 2018.

Functionalized Holmium-Doped Hollow Silica Nanospheres for Combined Sonodynamic and Hypoxia-Activated Therapy

Yanke Wang, Yan Liu, Huixia Wu, Jianping Zhang, Qiwei Tian and Shiping Yang, “Functionalized Holmium-Doped Hollow Silica Nanospheres for Combined Sonodynamic and Hypoxia-Activated Therapy”, Advanced Functional Meterials, 29(3), 1805764, 2019.

Echographic and physical characterization of albumin-stabilized nanobubbles

AkikoWatanabe, HongSheng, HitomiEndo, Loreto B.Feril, Yutaka Irie, Koichi Ogawa, SeyedehMoosavi-Nejad and KatsuroTachibana, “Echographic and physical characterization of albumin-stabilized nanobubbles”, Heliyon, 5(6), 2019.

Ursolic acid prevents doxorubicin‐induced cardiac toxicity in mice through eNOS activation and inhibition of eNOS uncoupling

Haiman Mu, Haiwen Liu, Jiayi Zhang, Jianhua Huang, Chen Zhu, Yue Lu, Yueping Shi and Yi Wang, “Ursolic acid prevents doxorubicin‐induced cardiac toxicity in mice through eNOS activation and inhibition of eNOS uncoupling”, Journal of Cellular and Molecular Medicine. 23:2174-2183, 2019.

In vivo fate of free and encapsulated iron oxide nanoparticles after injection of labelled stem cells

Sumaira Ashraf, Arthur Taylor, Jack Sharkey, Michael Barrow, Patricia Murray, Bettina Wilm, Harish Poptani, Matthew J. Rosseinsky, Dave J. Adams and Raphaël Lévy, “In vivo fate of free and encapsulated iron oxide nanoparticles after injection of labelled stem cells”, Royal Society of Chemistry, 1, P.367-377, 2019.

MiR-195-5p Promotes Cardiomyocyte Hypertrophy by Targeting MFN2 and FBXW7

Lei Wang, Dongze Qin, Hongtao Shi, Yanan Zhang, Hao Li, and Qinghua Han, “MiR-195-5p Promotes Cardiomyocyte Hypertrophy by Targeting MFN2 and FBXW7”, BioMed Research International, June 2019.

A Noninvasive Imaging Toolbox Indicates Limited Therapeutic Potential of Conditionally Activated Macrophages in a Mouse Model of Multiple Organ Dysfunction

Jack Sharkey, Lorenzo Ressel, Nathalie Brillant, Lauren Scarfe, Bettina Wilm, B. Kevin Park, and Patricia Murray, “A Noninvasive Imaging Toolbox Indicates Limited Therapeutic Potential of Conditionally Activated Macrophages in a Mouse Model of Multiple Organ Dysfunction”, Stem Cells International, April,2019.

Insulin-like growth factor binding protein related protein 1 knockdown attenuates hepatic fibrosis via the regulation of MMPs/TIMPs in mice

Jun-Jie Ren, Ting-Juan Huang, Qian-Qian Zhang, Hai-Yan Zhang, Xiao-Hong Guo, Hui-Qin Fan, Ren-Ke Li and Li-Xin Liu, “Insulin-like growth factor binding protein related protein 1 knockdown attenuates hepatic fibrosis via the regulation of MMPs/TIMPs in mice”, Hepatobiliary & Pancreatic Diseases International, 18(1), P.38-47, 2019.

Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics

Wei-Ting Ho, Jung-Shen Chang, San-Fang Chou, Wei-Lun Hwang, Po-Jen Shih, Shu-Wen Chang, Muh-Hwa Yang, Tzuu-Shuh Jou and I-Jong Wang, “Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics”, Journal of Molecular Medicine, 97(9), P.1345-1357, 2019.

Multimodal Imaging Techniques Show Differences in Homing Capacity Between Mesenchymal Stromal Cells and Macrophages in Mouse Renal Injury Models

Arthur Taylor, Jack Sharkey, Rachel Harwood, Lauren Scarfe, Michael Barrow, Matthew J. Rosseinsky, Dave J. Adams, Bettina Wilm and Patricia Murray, “Multimodal Imaging Techniques Show Differences in Homing Capacity Between Mesenchymal Stromal Cells and Macrophages in Mouse Renal Injury Models”, Molecular Imaging and Biology, Published: 10 December 2019.

Evaluation of antitumor immunity by a combination treatment of high-dose irradiation, anti-PDL1, and anti-angiogenic therapy in murine lung tumors

Jenny Ling‑Yu Chen, Chun Kai Pan, Yu‑Sen Huang, ·Ching‑Yi Tsai, Chun‑Wei Wang, Yu‑Li Lin, Sung‑Hsin Kuo and Ming‑Jium Shieh, “Evaluation of antitumor immunity by a combination treatment of high-dose irradiation, anti-PDL1, and anti-angiogenic therapy in murine lung tumors”, Cancer Immunology, Immunotherapy, Published: 06 August 2020.

The Potential Effect of Fucoidan on Inhibiting Epithelial-to-Mesenchymal Transition, Proliferation, and Increase in Apoptosis for Endometriosis Treatment: In Vivo and In Vitro Study

Li-Chun Chang, Yi-Fen Chiang, Hsin-Yuan Chen, Yun-Ju Huang, An-Chieh Liu, and Shih-Min Hsia, “The Potential Effect of Fucoidan on Inhibiting Epithelial-to-Mesenchymal Transition, Proliferation, and Increase in Apoptosis for Endometriosis Treatment: In Vivo and In Vitro Study”, Biomedicines, 8(11), 528, 2020.

Low-frequency dual-frequency ultrasound-mediated microbubble cavitation for transdermal minoxidil delivery and hair growth enhancement

Ai-Ho Liao, Keng-Hsien Lin, Ho-ChiaoChuang, Chih-HungTsai, Yi-Chun Lin, Chih-HungWang, Cheng-Ping Shih and Hao-Li Liu, “Low-frequency dual-frequency ultrasound-mediated microbubble cavitation for transdermal minoxidil delivery and hair growth enhancement”, Scientific Reports, 10:4338, 2020.

NIR dye-loaded mesoporous silica nanoparticles for a multifunctional theranostic platform: Visualization of tumor and ischemic lesions, and performance of photothermal therapy

Sang Bong Lee, Ho Won Lee, Bobby Aditya Darmawan, In-Kyu Lee, Sung Jin Cho, Jungwook Chin, Sang Kyoon Kim, Jong-Oh Park, Kil Soo Kim, Sang-Woo Lee, Jaetae Lee and Yong Hyun Jeon, “NIR dye-loaded mesoporous silica nanoparticles for a multifunctional theranostic platform: Visualization of tumor and ischemic lesions, and performance of photothermal therapy”, Journal of Industrial and Engineering Chemistry, Volume 88, P. 99-105, 2020.

miR‐26a attenuates cardiac apoptosis and fibrosis by targeting ataxia–telangiectasia mutated in myocardial infarction

Ming‐Hsien Chiang, Chan‐Jung Liang, Lung‐Chun Lin, Yi‐Fan Yang, Ching‐Chang Huang, Ying‐Hsien Chen, Hsien‐Li Kao, Yu‐Chen Chen, Shin‐Rong Ke, Chiang‐Wen Lee, Mao‐Shin Lin and Yuh‐Lien Chen, “miR‐26a attenuates cardiac apoptosis and fibrosis by targeting ataxia–telangiectasia mutated in myocardial infarction”, Journal of Cellular Physiology, P. 1-18, 2020.

Enhanced Radiosensitization for Cancer Treatment with Gold Nanoparticles through Sonoporation

Shao-Lun Lu, Wei-Wen Liu, Jason Chia-Hsien Cheng, Lien-Chieh Lin, Churng-Ren Chris Wang, and Pai-Chi Li, “Enhanced Radiosensitization for Cancer Treatment with Gold Nanoparticles through Sonoporation”, International Journal of Molecular Sciences, 21, 8370, 2020.

Heparanase from triple‑negative breast cancer and platelets acts as an enhancer of metastasis

Wen‑Jing Yang, Gan‑Lin Zhang, Ke‑Xin Cao, Xiao‑Ni Liu, Xiao‑Min Wang, Ming Wei Yu, Jin Ping Li and Guo‑Wang Yang, “Heparanase from triple‑negative breast cancer and platelets acts as an enhancer of metastasis”, International Journal of Oncology, P.890-904, 2020.

Bispecific Antibody Inhalation Therapy for Redirecting Stem Cells from the Lungs to Repair Heart Injury

Mengrui Liu, Halle Lutz, Dashuai Zhu, Ke Huang, Zhenhua Li, Phuong‐Uyen C Dinh, Junqing Gao, Yi Zhang and Ke Cheng, “Bispecific Antibody Inhalation Therapy for Redirecting Stem Cells from the Lungs to Repair Heart Injury”, Advanced Science, 19 November 2020.

MicroRNA-221/222 Mediates ADSC-Exosome-Induced Cardioprotection Against Ischemia/Reperfusion by Targeting PUMA and ETS-1

Tsai-Chun Lai, Tzu-Lin Lee, Yu-Chun Chang, Yu-Chen Chen, Shu-Rung Lin, Shu-Wha Lin, Chi-Ming Pu, Jaw-Shiun Tsai and Yuh-Lien Chen, “MicroRNA-221/222 Mediates ADSC-Exosome-Induced Cardioprotection Against Ischemia/Reperfusion by Targeting PUMA and ETS-1”, Frontiers in Cell and Developmental Biology, Vol.8, December 2020.

Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway

Tzu-Lin Lee, Tsai-Chun Lai, Shu-Rung Lin, Shu-Wha Lin, Yu-Chen Chen, Chi-Ming Pu, I-Ta Lee, Jaw-Shiun Tsai, Chiang-Wen Lee and Yuh-Lien Chen, “Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway”, Theranostics, 11(7):3131-3149, 2021.

Minoxidil-Coated Lysozyme-Shelled Microbubbes Combined With Ultrasound for the Enhancement of Hair Follicle Growth: Efficacy In Vitro and In Vivo

Ai-Ho Liao, Yu-Jhen Huang, Ho-Chiao Chuang, Chih-Hung Wang, Cheng-Ping Shih and Chien-Ping Chiang, “Minoxidil-Coated Lysozyme-Shelled Microbubbes Combined With Ultrasound for the Enhancement of Hair Follicle Growth: Efficacy In Vitro and In Vivo”, Frontiers in Pharmacology, 12: 668754, 2021.

Development of thermosensitive poloxamer 407-based microbubble gel with ultrasound mediation for inner ear drug delivery

Ai-Ho Liao, Cheng-Ping Shih, Ming-Wei Li, Yi-Chun Lin, Ho-Chiao Chuang and Chih-Hung Wang, “Development of thermosensitive poloxamer 407-based microbubble gel with ultrasound mediation for inner ear drug delivery”, Drug Delivery, 28(1), 2021.

A Shift in Tissue Stiffness During Hippocampal Maturation Correlates to the Pattern of Neurogenesis and Composition of the Extracellular Matrix

Youngjae Ryu, Misato Iwashita, Wonyoung Lee, Kenji Uchimura and Yoichi Kosodo, “A Shift in Tissue Stiffness During Hippocampal Maturation Correlates to the Pattern of Neurogenesis and Composition of the Extracellular Matrix”, Frontiers in Aging Neuroscience, 13:709620, 2021.

A Novel ALDH2 Activator AD-9308 Improves Diastolic and Systolic Myocardial Functions in Streptozotocin-Induced Diabetic Mice

Hsiao-Lin Lee, Siow-Wey Hee, Chin-Feng Hsuan, Wenjin Yang, Jing-Yong Huang, Ya-Ling Lin, Chih-Neng Hsu, Juey-Jen Hwang, Shiau-Mei Chen, Zhi-Zhong Ding, Tung-Yuan Lee, Yu-Chiao Lin, Feng-Chiao Tsai, Wei-Lun Su, Li-Yun Chueh, Meng-Lun Hsiehand, Che-Hong Chen, Daria Mochly-Rosen, Yi-Cheng Chang and Lee-Ming Chuang, “A Novel ALDH2 Activator AD-9308 Improves Diastolic and Systolic Myocardial Functions in Streptozotocin-Induced Diabetic Mice”, Antioxidants, 10(3):450, 2021.

Stepwise candidate drug screening for myopia control by using zebrafish, mouse, and Golden Syrian Hamster myopia models

Meng-Yin Lin, I-Tsen Lin, Yu-Ching Wu and I-Jong Wang, “Stepwise candidate drug screening for myopia control by using zebrafish, mouse, and Golden Syrian Hamster myopia models”, eBioMedicine part of THE LACENT Discovery Science, 65:103263, 2021.

5-Methoxytryptophan attenuates postinfarct cardiac injury by controlling oxidative stress and immune activation

Wan-Tseng Hsu, Ya-Hsuan Tseng, Hsiang-Yiang Jui, Chen-Chin Kuo, Kenneth K Wu, and Chii-Ming Lee, “5-Methoxytryptophan attenuates postinfarct cardiac injury by controlling oxidative stress and immune activation”, Journal of Molecular and Cellular Cardiology, 158, p.101-114, 2021.

Combined use of microbubbles of various sizes and single-transducer dual-frequency ultrasound for safe and efficient inner ear drug delivery

Ai-Ho Liao, Chih-Hung Wang, Bo-Han Wang, Yi-Chun Lin, Ho-Chiao Chuang, Hao-Li Liu and Cheng-Ping Shih, “Combined use of microbubbles of various sizes and single-transducer dual-frequency ultrasound for safe and efficient inner ear drug delivery”, Bioengineering and Translational Medicine, 2022.

Global profiling of protein lysine malonylation in mouse cardiac hypertrophy

Li-Fei Wu, De-Ping Wang, Jing Shen, Li-Juan Gao, Ying Zhou, Qing-Hua Liu and Ji-Min Cao, “Global profiling of protein lysine malonylation in mouse cardiac hypertrophy”, Journal of Proteomics, 266, 2022.

Longitudinal shear wave elasticity measurements of millimeter-sized biomaterials using a single-element transducer platform

Shao-Lun Lu, Pei-Yu Chao, Wei-Wen Liu, Kun Han, Jason Chia-Hsien Cheng and Pai-Chi Li, “Longitudinal shear wave elasticity measurements of millimeter-sized biomaterials using a single-element transducer platform”, PLoS One, 17(4), 2022.

Allogeneic Expanded Human Peripheral NK Cells Control Prostate Cancer Growth in a Preclinical Mouse Model of Castration-Resistant Prostate Cancer

Fangming Wang, Xuejiao Dong, Jing Wang, Feiya Yang, Donghua Liu, Jianlin Ma, Shuai Liu, Dehua Chang and Nianzeng Xing, “Allogeneic Expanded Human Peripheral NK Cells Control Prostate Cancer Growth in a Preclinical Mouse Model of Castration-Resistant Prostate Cancer”, Journal of Immunology Research, 2022.

Ultrasound shear-wave computed tomography for elasticity imaging

Geng-Shi Jeng, Chia-Lun Yeh, Chia-Lin Lee, Yung-Shao Yang, Ling-Yi Tseng and Pai-Chi Li, “Ultrasound shear-wave computed tomography for elasticity imaging”, Applied Physics Letters, 121(4), 2022.

Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction

Junlang Li, Yongbo Lv, Dashuai Zhu, Xuan Mei, Ke Huang, Xianyun Wang, Zhenhua Li, Sichen Zhang, Shiqi Hu, Kristen D. Popowski, Ke Cheng and Juan Wang, “Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction”, Chemical Engineering Journal, 427, 2022.

The Imaging Performance of Preclinical Ultrasound Scanners Using the Edinburgh Pipe Phantom

Carmel M Moran, Christopher McLeod, Karne McBride, Scott Inglis, Adrian JW Thomson and Stephen D Pye, “The Imaging Performance of Preclinical Ultrasound Scanners Using the Edinburgh Pipe Phantom”, Frontiers in Physics: Medical Physics and Imaging, 10, 2022.

Cancer "Avatars": Patient-Derived Xenograft Growth Correlation with Postoperative Recurrence and Survival in Pancreaticobiliary Cancer

Lynch, Isaac T BA; Abdelrahman, Amro M MBBS, MS; Alva-Ruiz, Roberto MD; Fogliati, Alessandro MD; Graham, Rondell P MBBS; Smoot, Rory MD; Truty, Mark J MD, MS, FACS, “Cancer “Avatars”: Patient-Derived Xenograft Growth Correlation with Postoperative Recurrence and Survival in Pancreaticobiliary Cancer”, Frontiers in Physics: Medical Physics and Imaging, Journal of the American College of Surgeons, 237(3), p.483-500, 2023.

Treatment efficacy of low-dose 5-fluorouracil with ultrasound in mediating 5-fluorouracil-loaded microbubble cavitation in head and neck cancer

Ai-Ho Liao, Yu-An Lee, Dao-Lung Lin, Ho-Chiao Chuang, Jehng-Kang Wang, Ching-En Chang, Hsiang-Tzu Li, Ting-Yi Wu, Cheng-Ping Shih, Chih-Hung Wang and Yueng-Hsiang Chu, “Treatment efficacy of low-dose 5-fluorouracil with ultrasound in mediating 5-fluorouracil-loaded microbubble cavitation in head and neck cancer”, Drug Delivery, 30(1), p.1-13, 2023.

Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair

Dashuai Zhu, Shuo Liu, Ke Huang, Junlang Li, Xuan Mei, Zhenhua Li and Ke Cheng, “Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair”, European Heart Journal, 44(19), p.1748-1760, 2023.

Overexpression of GRK2 in vascular smooth muscle leads to inappropriate hypertension and acute heart failure as in clinical scenario 1

Hiroki Yano, Kenji Onoue, Shiho Tokinaga, Tomoko Ioka, Satomi Ishihara, Yukihiro Hashimoto, Yasuki Nakada, Hitoshi Nakagawa, Tomoya Ueda, Ayako Seno, Taku Nishida, Makoto Watanabe and Yoshihiko Saito, “Overexpression of GRK2 in vascular smooth muscle leads to inappropriate hypertension and acute heart failure as in clinical scenario 1”, Scientific Reports, 13, Article number: 7707, 2023.

Synaptotagmin-7 mediates cardiac hypertrophy by targeting autophagy

Teng Sun, Yu Han, Jia-Lei Li, Shuang Wang, Zhi-Jie Jing, Zi Yan, Lan Zhou, Lin Zuo, Jun-Li Yang, and Ji-Min Cao, “Synaptotagmin-7 mediates cardiac hypertrophy by targeting autophagy”, The FEBS Journal, 19, 2023.

Pharmacological Inhibition of Gasdermin D Suppresses Angiotensin II-Induced Experimental Abdominal Aortic Aneurysms

Jia Guo, Jinyun Shi, Min Qin, Yan Wang, Zhidong Li, Takahiro Shoji, Toru Ikezoe, Yingbin Ge, and Baohui Xu, “Pharmacological Inhibition of Gasdermin D Suppresses Angiotensin II-Induced Experimental Abdominal Aortic Aneurysms”, Biomolecules, 13(6):899, 2023.

Optimizing Cell Therapy by Sorting Cells with High Extracellular Vesicle Secretion

Doyeon Koo, Xiao Cheng, Shreya Udani, Dashuai Zhu, Junlang Li, Brian Hall, Natalie Tsubamoto, Shiqi Hu, Jina Ko, Ke Cheng and Dino Di Carlo, “Optimizing Cell Therapy by Sorting Cells with High Extracellular Vesicle Secretion”, bioRxiv, 2023.

A Novel Needle Mouse Model of Vascular Cognitive Impairment and Dementia

Zhongfang Weng, Catherine Cao, Nadezda A. Stepicheva, Fenghua Chen, Lesley M. Foley, Sarah Cao, Mohammad Iqbal H. Bhuiyan, Qingde Wang, Yuan Wang, T. Kevin Hitchens, Dandan Sun and Guodong Cao, “A Novel Needle Mouse Model of Vascular Cognitive Impairment and Dementia”, Journal of Neuroscience, 43(44), 2023.

Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity

Chia Yee Tan, Pui Shi Chan, Hansen Tan, Sung Wei Tan, Chang Jie Mick Lee, Jiong-Wei Wang, Shu Ye, Hendrikje Werner, Ying Jie Loh, Yin Loon Lee, Matthew Ackers-Johnson, Roger S. Y. Foo and Jianming Jiang, “Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity”, Journal of Translational Medicine, Vol. 21, Article number: 690, 2023.

Alleviating Effects of Ovatodiolide and Antcin K Supplements on High-Fat Diet-Induced Cardiovascular Dysfunction in ApoE-Knockout Mice by Attenuating Oxidative Stress

Chen-Wen Lu, Wen-Jhen Wu, Thi Kim Ngan Nguyen, Szu-Chuan Shen, Yeh-B. Wu, Hui-Ju Liang, and Chung-Hsin Wu, “Alleviating Effects of Ovatodiolide and Antcin K Supplements on High-Fat Diet-Induced Cardiovascular Dysfunction in ApoE-Knockout Mice by Attenuating Oxidative Stress”, Nutrients, 15(18), 4074, 2023.

Establishment of ultrasound-responsive SonoBacteriaBot for targeted drug delivery and controlled release

Meng Du, Ting Wang Wu, Renjie Feng, Penghui Zeng and Zhiyi Chen, “Establishment of ultrasound-responsive SonoBacteriaBot for targeted drug delivery and controlled release”, Front. Bioeng. Biotechnol, 2023.

VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid–liquid phase separation

Yuma Horii, Shoichi Matsuda, Chikashi Toyota, Takumi Morinaga, Takeo Nakaya, Soken Tsuchiya, Masaki Ohmuraya, Takanori Hironaka, Ryo Yoshiki, Kotaro Kasai, Yuto Yamauchi, Noburo Takizawa, Akiomi Nagasaka, Akira Tanaka, Hidetaka Kosako and Michio Nakaya, “VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid–liquid phase separation”, Nature Communications, 14, Article number: 550, 2023.

RETRACTED ARTICLE: Liquiritin reduces ferroptosis in doxorubicin-induced cardiotoxicity through targeting SLC7A11/GPX4 pathway

Mei Wang, Meng Liu, Lijing Tang, Lixian Shen, Junhui Xiao and Rong Li, “RETRACTED ARTICLE: Liquiritin reduces ferroptosis in doxorubicin-induced cardiotoxicity through targeting SLC7A11/GPX4 pathway”, Naunyn-Schmiedeberg's Archives of Pharmacology, Vol. 397, p. 627, 2024.

Treatment with a new barbituric acid derivative suppresses diet-induced metabolic dysfunction and non-alcoholic fatty liver disease in mice

Fat-Moon Suk, Fang-Yu Hsu, Ming-Hua Hsu, Wan-Chun Chiu, Cheng-Chieh Fang, Tzu-Lang Chen and Yi-Jen Liao, “Treatment with a new barbituric acid derivative suppresses diet-induced metabolic dysfunction and non-alcoholic fatty liver disease in mice”, Life Sciences, Vol. 336, 2024.

Prodigy

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Ultrafast plane wave imaging based pulsed magnetomotive ultrasound

Pei-Hsien Ting, Yi-Da Kang, San-Yuan Chen, Meng-Lin Li, “Ultrafast plane wave imaging based pulsed magnetomotive ultrasound”, IEEE International Ultrasonics Symposium(IUS), Chicago Illinois, USA, September 3-6, 2014.

Hybrid optoacoustic tomography and pulse-echo ultrasonography using concave arrays

Merčep, E., Jeng, G., Morscher, S., Pai-Chi Li, Razansky, D., “Hybrid optoacoustic tomography and pulse-echo ultrasonography using concave arrays”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 62(9), p.1651-1661, 2015.

Low-complexity adaptive beamforming using autocorrelation-based generalized coherence factor

Yong-Qi Xing, Shue-Han Jiang, Gency Jeng, Che-Chou Shen, “Low-complexity adaptive beamforming using autocorrelation-based generalized coherence factor”, IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, October 21-24, 2015.

Ultrafast pulsed magnetomotive ultrasound imaging of sentinel lymph nodes: Small animal study

Yu-Chun Huang , Jieh-Yuan Houng, Yi-Da Kang, San-Yuan Chen, Meng-Lin Li, “Ultrafast pulsed magnetomotive ultrasound imaging of sentinel lymph nodes: Small animal study”, IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, October 21-24, 2015.

Linear array beamformation using virtual sub-wavelength receiving elements

Shao-Yu Peng, Meng-Lin Li, “Linear array beamformation using virtual sub-wavelength receiving elements”, IEEE International Ultrasonics Symposium (IUS), Taipei, Taiwan, October 21-24, 2015.

Sound speed optimization for ultrasound beamforming using differential phase gradient between sub-apertures

Che-Chou Shen, Hsiao-Chi Yang, Gency Jeng, “Sound speed optimization for ultrasound beamforming using differential phase gradient between sub-apertures”, IEEE International Ultrasonics Symposium (IUS), Tour, France, September 18-21, 2016.

Autocorrelation-based generalized coherence factor for low-complexity adaptive beamforming

Che-Chou Shen, Yong-Qi Xing and Gency Jeng, “Autocorrelation-based generalized coherence factor for low-complexity adaptive beamforming”, Ultrasonics, 72, P.177-183, 2016.

Transform-Based Channel-Data Compression to Improve the Performance of a Real-Time GPU-Based Software Beamformer

U.-Wai Lok and Pai-Chi Li, “Transform-Based Channel-Data Compression to Improve the Performance of a Real-Time GPU-Based Software Beamformer”, IEEE Transactions on Ultrasonics, 63(3), P369-380, 2016.

Photoacoustic Elasticity Imaging for Soft Tissue-mimicking Phantom

Nai-Zhang Feng, Ying Fu, Tong Wang, and Ming-Jian Sun, “Photoacoustic Elasticity Imaging for Soft Tissue-mimicking Phantom”, International Conference on Photonics and Imaging in Biology and Medicine, Suzhou, China, September 26-28, 2017.

Backward-mode ultrafast pulsed magnetomotive ultrasound

Ming-Chen Lu, Jieh-Yuan Houng, Meng-Lin Li, “Backward-mode ultrafast pulsed magnetomotive ultrasound”, IEEE International Ultrasonics Symposium (IUS), Washington, DC, USA, September 6-9, 2017.

Needle guidance using laser generated leaky acoustic waves

Yi-An Wang , U-Wai Lok, Pai-Chi Li, “Needle guidance using laser generated leaky acoustic waves”, IEEE International Ultrasonics Symposium (IUS), Washington, DC, USA, September 6-9, 2017.

Compressed sensing in synthetic aperture photoacoustic tomography based on a linear-array ultrasound transducer

Xiang-Wei Lin, Nai-Zhang Feng, Ya-Wei Qu, De-Ying Chen, Yi Shen, and Ming-Jian Sun, “Compressed sensing in synthetic aperture photoacoustic tomography based on a linear-array ultrasound transducer”, Chinese Optics Letters, 15(10), P. 101102, 2017.

Monte Carlo light transport-based blood vessel quantification using linear array photoacoustic tomography

Xiang-Wei Lin, Ming-Jian Sun, Nai-Zhang Feng, De-Peng Hu, and Yi Shen, “Monte Carlo light transport-based blood vessel quantification using linear array photoacoustic tomography”, Chinese Optics Letters, 15(11), P. 111701, 2017.

Adaptive optimization of ultrasound beamforming sound velocity using sub-aperture differential phase gradient

Che-Chou Shen, Hsiao-Chi Yang, “Adaptive optimization of ultrasound beamforming sound velocity using sub-aperture differential phase gradient”, Ultrasonics, 79, P. 52-59, 2017.

Linear array-based real-time photoacoustic imaging system with a compact coaxial excitation handheld probe for noninvasive sentinel lymph node mapping

Mucong Li, Chengbo Liu, Xiaojing Gong, Rongqin Zheng, Yuanyuan Bai, Muyue Xing, Xuemin Du, Xiaoyang Liu, Jing Zeng, Riqiang Lin, Huichao Zhou, Shouju Wang, Guangming Lu, Wen Zhu, Chihua Fang, and Lian Song, “Linear array-based real-time photoacoustic imaging system with a compact coaxial excitation handheld probe for noninvasive sentinel lymph node mapping”, Biomedical Optics Express, 9(4), P.1408-1422, 2018.

Laser generated leaky acoustic waves for needle visualization

Kei-Wen Wu, Yi-An Wang and Pai-Chi Li, “Laser generated leaky acoustic waves for needle visualization”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, PP(99), P.1-1, 2018.

Synthetic transmit aperture beamforming for sound velocity estimation using channel-domain differential phase gradient–A phantom study

Che-Chou Shen, Sheng-Hsuan Hsiao, and Yen-Chung Lin, “Synthetic transmit aperture beamforming for sound velocity estimation using channel-domain differential phase gradient–A phantom study”, Ultrasonics, 94,P.183-191,2019.

Large Depth Focus-Tunable Photoacoustic Tomography Based On Clinical Ultrasound Array Transducer

Ruian Liu, Liangzhong Xiang, Da Xing, Jiandong Li, Huan Qin, Weicheng Zhang, and Sihua Yang, “Large Depth Focus-Tunable Photoacoustic Tomography Based On Clinical Ultrasound Array Transducer”, Applied Physics Letters, 113, Oct. 2018.

Ultrafast Doppler Observation in Rat Stroke Model-Comparison with High Field Magnetic Resonance Imaging

Yu-Chieh JillKao and Bao-Yu Hsieh, “Ultrafast Doppler Observation in Rat Stroke Model-Comparison with High Field Magnetic Resonance Imaging”, IEEE International Ultrasonics Symposium (IUS), 22-25 Oct. 2018.

Laser Generated Leaky Acoustic Waves for Needle Visualization

Kai-Wen Wu, Yi-An Wang and Pai-Chi Li, “Laser Generated Leaky Acoustic Waves for Needle Visualization”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 65(4), P.546-556, 2018.

Microbeamforming With Error Compensation

U-Wai Lok and Pai-Chi Li, “Microbeamforming With Error Compensation”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 65(7), P.1153-1165, 2018.

Ankle Dorsiflexion Strength Monitoring by Combining Sonomyography and Electromyography

Qiang Zhang, Zhiyu Sheng, Frank Moore-Clingenpeel, Kang Kim, Nitin Sharma, “Ankle Dorsiflexion Strength Monitoring by Combining Sonomyography and Electromyography”, ICORR, 24-28 June 2019.

Synchronized Optical and Acoustic Droplet Vaporization for Effective Sonoporation

Wei-Wen Liu, Sy-Han Huang, Pai-Chi Li, “Synchronized Optical and Acoustic Droplet Vaporization for Effective Sonoporation”, Pharmaceutics, 11(6), 279, 2019.

Real-time interleaved photoacoustic and ultrasound imaging for guiding interventional procedures

Weicheng Zhang, Jiandong Li, Sihua Yang, “Real-time interleaved photoacoustic and ultrasound imaging for guiding interventional procedures”, Applied Acoustics, 156, P. 1-6, 2019.

Quantitative Reconstruction of Absorption Coefficients for Photoacoustic Tomography

Yang Liu, Mingjian Sun, Ting Liu, Yiming Ma, Depeng Hu, Chao Li and Naizhang Feng, “Quantitative Reconstruction of Absorption Coefficients for Photoacoustic Tomography”, Applied Sciences, 9(6),1187, 2019.

Ultrasound Baseband Delay-Multiply-and-Sum (BB-DMAS) nonlinear beamforming

Che-Chou Shen and Pei-Ying Hsieh, “Ultrasound Baseband Delay-Multiply-and-Sum (BB-DMAS) nonlinear beamforming”, Ultrasonics, 96, P.165-174, 2019.

Quantitative Assessment of Changes in Muscle Contractility Due to Fatigue During NMES: An Ultrasound Imaging Approach

Zhiyu Sheng, Nitin Sharma and Kang Kim, “Quantitative Assessment of Changes in Muscle Contractility Due to Fatigue During NMES: An Ultrasound Imaging Approach”, IEEE Transactions on Biomedical Engineering, P.1-1, June 2019.

Toward Real Time Backward-Mode Pulsed Magnetomotive Ultrasound

Wei-Hsiang Shen and Meng-Lin Li, “Toward Real Time Backward-Mode Pulsed Magnetomotive Ultrasound”, IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, 2019.

Improved Backward Mode Pulsed Magnetomotive Ultrasound via Pre-magnetization of Superparamagnetic Iron Oxide Nanoparticles

Hong-Wei Wang, Chih-Chia Huang and Meng-Lin Li, “Improved Backward Mode Pulsed Magnetomotive Ultrasound via Pre-magnetization of Superparamagnetic Iron Oxide Nanoparticles”, IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, 2019.

Golay-Encoded Pulse-Inversion Subtraction for Real-Time Ultrasound Monitoring of HIFU Therapy

Guan-Heng Lai, Pai-Chi Li and Che-Chou Shen, “Golay-Encoded Pulse-Inversion Subtraction for Real-Time Ultrasound Monitoring of HIFU Therapy”, IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, 2019.

Detection of KCl Induced Cortical Spreading Depolarization (CSD) with Dynamic Ultrafast Doppler

Ning Zhou, Yu-Chieh Jill Kao, Yu-Ying Mei, Yi-Pei Lin, Dong-Chuan Wu and Bao-Yu Hsieh, “Detection of KCl Induced Cortical Spreading Depolarization (CSD) with Dynamic Ultrafast Doppler”, IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, 2019.

Monitoring of Vascular Response to Peri-Infarct Depolarization (PID) in Photothrombotic Stroke Animal Model

Yu-Chieh Jill Kao and Bao-Yu Hsieh, “Monitoring of Vascular Response to Peri-Infarct Depolarization (PID) in Photothrombotic Stroke Animal Model”, IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, 2019.

A Flexible Speckle Reduction Strategy using Thomson’s Multitaper in High-order DMAS Beamforming

Che-Chou Shen and Pei-Ying Hsieh, “A Flexible Speckle Reduction Strategy using Thomson’s Multitaper in High-order DMAS Beamforming”, IEEE International Ultrasonics Symposium (IUS), Glasgow, Scotland, October 6-9, 2019.

Prediction of Ankle Dorsiflexion Moment by Combined Ultrasound Sonography and Electromyography

Qiang Zhang, Kang Kim and Nitin Sharma, “Prediction of Ankle Dorsiflexion Moment by Combined Ultrasound Sonography and Electromyography”, IEEE Transactions on Neural Systems and Rehabilitation Engineering (Early Access), 2019.

Ultrasound DMAS beamforming for estimation of tissue speed of sound in multi-angle plane-wave imaging

Kuan-Lin Tu, Che-Chou Shen and Yen-Chen Chu, “Ultrasound DMAS beamforming for estimation of tissue speed of sound in multi-angle plane-wave imaging”, IEEE International Ultrasonics Symposium (IUS), 7-11 Sept. 2020.

Analysis of Tremor During Grasp Using Ultrasound Imaging: Preliminary Study

Ashwin Iyer, Zhiyu Sheng, Qiang Zhang, Kang Kim and Nitin Sharma, “Analysis of Tremor During Grasp Using Ultrasound Imaging: Preliminary Study”, 2020 8th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob), New York, USA. Nov 29 - Dec 1, 2020.

Radiotherapy dose characterization of gel dosimetry using shear wave elasticity imaging

Wei‐Huan Xie, Chun‐Ting Su, Yu‐Chieh Jill Kao, Tung‐Hao Chang, Yuan‐Jen Chang, Chun‐Hsu Yao and Bao‐Yu Hsieh, “Radiotherapy dose characterization of gel dosimetry using shear wave elasticity imaging”, Medical Physics, 47(3), p.1404-1410, 2020.

Estimation of ultrasound echogenicity map from B-mode images using convolutional neural network

Jui-En Yang, Che-Chou Shen and Ri-Cheng Lin, “Estimation of ultrasound echogenicity map from B-mode images using convolutional neural network”, IEEE International Ultrasonics Symposium (IUS), 7-11 Sept. 2020.

Ultra-High-Frame-Rate Ultrasound Monitoring of Muscle Contractility Changes Due to Neuromuscular Electrical Stimulation

Zhiyu Sheng, Nitin Sharma and Kang Kim, “Ultra-High-Frame-Rate Ultrasound Monitoring of Muscle Contractility Changes Due to Neuromuscular Electrical Stimulation”, Biomedical Engineering Society, 14 May 2020.

Volitional Contractility Assessment of Plantar Flexors by Using Non-invasive Neuromuscular Measurements

Qiang Zhang, Ashwin Iyer, Kang Kim and Nitin Sharma, “Volitional Contractility Assessment of Plantar Flexors by Using Non-invasive Neuromuscular Measurements”, 2020 8th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob), New York, USA. Nov 29 - Dec 1, 2020.

Evaluation of Non-Invasive Ankle Joint Effort Prediction Methods for Use in Neurorehabilitation Using Electromyography and Ultrasound Imaging

Qiang Zhang, Ashwin Iyer, Kang Kim and Nitin Sharma, “Evaluation of Non-Invasive Ankle Joint Effort Prediction Methods for Use in Neurorehabilitation Using Electromyography and Ultrasound Imaging”, IEEE Transactions on Biomedical Engineering, August 2020.

Correlation-Based Doppler-Angle Estimation with Plane-Wave Excitation

U-Wai Lok, Fang-Yu Lin, Chia-Lun Yeh and Pai-Chi Li, “Correlation-Based Doppler-Angle Estimation with Plane-Wave Excitation”, Informatics in Medicine Unlocked, vol.19, 2020.

Estimation of Ultrasound Echogenicity Map from B-Mode Images Using Convolutional Neural Network

Che-Chou Shen and Jui-En Yang, “Estimation of Ultrasound Echogenicity Map from B-Mode Images Using Convolutional Neural Network”, Sensors, 20(17), 4931, 2020.

Dual-Frequency Chirp Excitation for Passive Cavitation Imaging in the Brain

Hsiang-Ching Lin, Ching-Hsiang Fan, Yi-Ju Ho and Chih-Kuang Yeh, “Dual-Frequency Chirp Excitation for Passive Cavitation Imaging in the Brain”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 67(6), 2020.

Ultrafast Ultrasound-Derived Muscle Strain Measure Correlates with Carotid Local Pulse Wave Velocity in Habitual Resistance-Trained Individuals

Hsin-Fu Lin, Yi-Hung Liao and Pai-Chi Li, “Ultrafast Ultrasound-Derived Muscle Strain Measure Correlates with Carotid Local Pulse Wave Velocity in Habitual Resistance-Trained Individuals”, Applied Sciences, 11(18), 8783, 2021.

Ultra-High-Frame-Rate Ultrasound Monitoring of Muscle Contractility Changes Due to Neuromuscular Electrical Stimulation

Zhiyu Sheng, Nitin Sharma and Kang Kim, “Ultra-High-Frame-Rate Ultrasound Monitoring of Muscle Contractility Changes Due to Neuromuscular Electrical Stimulation”, Annals of Biomedical Engineering, vol. 49, p.262-275, 2021.

DMAS Beamforming with Complementary Subset Transmit for Ultrasound Coherence-Based Power Doppler Detection in Multi-Angle Plane-Wave Imaging

Che-Chou Shen and Yen-Chen Chu, “DMAS Beamforming with Complementary Subset Transmit for Ultrasound Coherence-Based Power Doppler Detection in Multi-Angle Plane-Wave Imaging”, Sensors, 21(14), 4856, 2021.

Elevational motion estimation for 3D ultrasound with machine learning and a speckle generating gel pad

Ching-Yen Lee, U-Wai Lok and Pai-Chi Li, “Elevational motion estimation for 3D ultrasound with machine learning and a speckle generating gel pad”, Proc. SPIE 11792, International Forum on Medical Imaging in Asia 2021, 117920U, 20 April 2021.

Closed-loop photothermal therapy system based on photoacoustic and ultrasonic dual-mode temperature feedback

Yiming Ma, Zhigang Lei, Yuanyuan Gao and Mingjian Sun, “Closed-loop photothermal therapy system based on photoacoustic and ultrasonic dual-mode temperature feedback”, IEEE International Ultrasonics Symposium (IUS), 11-16 Sept. 2021.

Stereoscopic photoacoustic imaging of radial artery for preoperative evaluation of coronary intervention

Tengsen Qiu, Yihao Duan and Zhongwen Cheng, “Stereoscopic photoacoustic imaging of radial artery for preoperative evaluation of coronary intervention”, Applied Physics Express, 14(5), 2021.

Computationally efficient minimum-variance baseband delay-multiply-and-sum beamforming for adjustable enhancement of ultrasound image resolution

Che-ChouShen, “Computationally efficient minimum-variance baseband delay-multiply-and-sum beamforming for adjustable enhancement of ultrasound image resolution”, Ultrasonics, Vol.112, 2021.

Intelligent photothermal treatment method based on photoacoustic and photothermal probe assistance

Yiming Ma, Liyong Ma, Yuanyuan Gao and Mingjian Sun, “Intelligent photothermal treatment method based on photoacoustic and photothermal probe assistance”, Proc. SPIE 11781, 4th Optics Young Scientist Summit (OYSS 2020), 1178121, 28 Feb. 2021.

Spherical-matching hyperbolic-array photoacoustic computed tomography

Yihao Duan, Zhongwen Cheng, Tengsen Qiu, Liewei Wen and Kedi Xiong, “Spherical-matching hyperbolic-array photoacoustic computed tomography”, Journal of Biophotonics, 14(6), 2021.

Laser-Generated Leaky Acoustic Wave Imaging for Interventional Guidewire Guidance

Geng-Shi Jeng, Yi-An Wang, Ping-Yang Liu and Pai-Chi Li, “Laser-Generated Leaky Acoustic Wave Imaging for Interventional Guidewire Guidance”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 68(7), p. 2496 – 2506, 2021.

An Excitation-Reception Collinear Probe for Ultrasonic, Photoacoustic, and Thermoacoustic Tri-Modal Volumetric Imaging

Zhongwen Cheng, Linghua Wu, Tengsen Qiu, Yihao Duan, Huan Qin, Jun Hu and Sihua Yang, “An Excitation-Reception Collinear Probe for Ultrasonic, Photoacoustic, and Thermoacoustic Tri-Modal Volumetric Imaging”, IEEE Transactions on Medical Imaging, 40(12), p.3498 - 3506, 2021.

Ultrasound Echogenicity as an Indicator of Muscle Fatigue during Functional Electrical Stimulation

Qiang Zhang, Ashwin Iyer, Krysten Lambeth, Kang Kim and Nitin Sharma, “Ultrasound Echogenicity as an Indicator of Muscle Fatigue during Functional Electrical Stimulation”, Sensors, 22(1):335, 2022.

Transmit Delay and Standard Deviation Beamforming to Enhance Specular Reflections in Synthetic Transmit Aperture Imaging

Cheng-Hao Lin and Che-Chou Shen, “Transmit Delay and Standard Deviation Beamforming to Enhance Specular Reflections in Synthetic Transmit Aperture Imaging”, IEEE International Ultrasonics Symposium (IUS), Venice, Italy, 10-13 Oct., 2022.

Ultrasound-Based Sensing and Control of Functional Electrical Stimulation for Ankle Joint Dorsiflexion: Preliminary Study

Qiang Zhang, Ashwin Iyer, and Nitin Sharma, “Ultrasound-Based Sensing and Control of Functional Electrical Stimulation for Ankle Joint Dorsiflexion: Preliminary Study”, International Symposium on Wearable Robotics, Wearable Robotics: Challenges and Trends, Biosystems & Biorobotics 27.

Noninvasive photoacoustic computed tomography/ultrasound imaging to identify high-risk atherosclerotic plaques

Xuewei Liu, Rongkang Gao, Chiyun Chen, Xiaobo Li, Chen Yu, Yejia Chen, Hongbin Liang, Min Xiao, Lei Dai, Shifeng Qiu, Xiaoyu Xin, Liang Song, Jinbin Liu, Chengbo Liu and Jiancheng Xiu, “Noninvasive photoacoustic computed tomography/ultrasound imaging to identify high-risk atherosclerotic plaques”, European Journal of Nuclear Medicine and Molecular Imaging, 49, p.4601–4615, 2022.

A Hybrid Knee Exoskeleton Using Real-Time Ultrasound-Based Muscle Fatigue Assessment

Z. Sheng, A. Iyer, Z. Sun, K. Kim and N. Sharma, “A Hybrid Knee Exoskeleton Using Real-Time Ultrasound-Based Muscle Fatigue Assessment”, IEEE/ASME Transactions on Mechatronics, 27(4), p. 1854-1862, 2022.

Golay-Encoded Ultrasound Monitoring of Simultaneous High-Intensity Focused Ultrasound Treatment: A Phantom Study

Che-Chou Shen, Ri-Cheng Lin and Nien-Hung Wu, “Golay-Encoded Ultrasound Monitoring of Simultaneous High-Intensity Focused Ultrasound Treatment: A Phantom Study”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 69(4), p.1370-1381, 2022.

Fused ultrasound and electromyography-driven neuromuscular model to improve plantarflexion moment prediction across walking speeds

Qiang Zhang, Natalie Fragnito, Jason R. Franz and Nitin Sharma, “Fused ultrasound and electromyography-driven neuromuscular model to improve plantarflexion moment prediction across walking speeds”, Journal of NeuroEngineering and Rehabilitation, 19, Article number: 86, 2022.

Vascular responses of penetrating vessels during cortical spreading depolarization with ultrasound dynamic ultrafast Doppler imaging

Bao-Yu Hsieh, Yu-Chieh Jill Kao, Ning Zhou, Yi-Pei Lin, Yu-Ying Mei, Sung-Yu Chu and Dong-Chuan Wu, “Vascular responses of penetrating vessels during cortical spreading depolarization with ultrasound dynamic ultrafast Doppler imaging”, Frontiers in Neuroscience, 16, 2022.

A deep learning method to predict ankle joint moment during walking at different speeds with ultrasound imaging: A framework for assistive devices control

Qiang Zhang, Natalie Fragnito, Xuefeng Bao and Nitin Sharma, “A deep learning method to predict ankle joint moment during walking at different speeds with ultrasound imaging: A framework for assistive devices control”, Wearable Technologies, 3,e20, 2022.

Polarization microwave-induced thermoacoustic imaging for quantitative characterization of deep biological tissue microstructures

Yujing Li, Shanxiang Zhang, Linghua Wu, Zhongwen Cheng, Zhenhui Zhang, Haohao Wang, Shuxiang Zhao, Mingyang Ren, Sihua Yang, Da Xing, and Huan Qin, “Polarization microwave-induced thermoacoustic imaging for quantitative characterization of deep biological tissue microstructures”, Photonics Research, 10(5), p.1297-1306, 2022.

Ultrasound Imaging-Based Closed-Loop Control of Functional Electrical Stimulationfor Drop Foot Correction

Qiang Zhang, Krysten Lambeth, Ashwin Iyer, Ziyue Sun and Nitin Sharma, “Ultrasound Imaging-Based Closed-Loop Control of Functional Electrical Stimulationfor Drop Foot Correction”, IEEE Transactions on Control Systems Technology, p.1-17, 2022.

Nonlinear System Identification of Tremors Dynamics: A Data-driven Approximation Using Koopman Operator Theory

Xiangming Xue, Ashwin Iyer, Daniel Roque, and Nitin Sharma, “Nonlinear System Identification of Tremors Dynamics: A Data-driven Approximation Using Koopman Operator Theory”, 2023 11th International IEEE/EMBS Conference on Neural Engineering (NER), Baltimore, MD, USA, p. 1-4, 2023.

Towards ultrasound imaging-based closed-loop peripheral nerve stimulation for tremor suppression

Nitin Sharma, Xiangming Xue, Ashwin Iyer, Xiaoning Jiang and Daniel Roque, “Towards ultrasound imaging-based closed-loop peripheral nerve stimulation for tremor suppression”, Current Opinion in Biomedical Engineering, Vol. 28, 2023.

A Dual-Mode Spherically Focused Theranostic Phased Array for CNS Application

Chun Fu, Tzu-Tsen Hsieh, and Hao-Li Liu, “A Dual-Mode Spherically Focused Theranostic Phased Array for CNS Application”, 2023 IEEE International Ultrasonics Symposium (IUS), Montreal, QC, Canada, p.1-4, 2023.

Multi-Wavelength Photoacoustic Temperature Feedback Based Photothermal Therapy Method and System

Yiming Ma, Yang Liu, Zhigang Lei, Zezheng Qin, Yi Shen and Mingjian Sun, “Multi-Wavelength Photoacoustic Temperature Feedback Based Photothermal Therapy Method and System”, Pharmaceutics, 15(2), 2023.

Improved source localization in passive acoustic mapping using delay-multiply-and-sum beamforming with virtually augmented aperture

Che-Chou Shen, You-An Chen, and Hsin-Yu Ku, “Improved source localization in passive acoustic mapping using delay-multiply-and-sum beamforming with virtually augmented aperture”, Ultrasonics, Vol. 135, 2023.

Visual Perception and Convolutional Neural Network-Based Robotic Autonomous Lung Ultrasound Scanning Localization System

Boheng Zhang, Haibo Cong, Yi Shen and Mingjian Sun, “Visual Perception and Convolutional Neural Network-Based Robotic Autonomous Lung Ultrasound Scanning Localization System”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 70(9), p.961-974, 2023.

A neural network estimation model based light dose control method and system for low-temperature photothermal therapy

Yiming Ma, Zhigang Lei, Dongjian Wu, Yi Shen and Mingjian Sun, “A neural network estimation model based light dose control method and system for low-temperature photothermal therapy”, Biomedical Signal Processing and Control, Vol. 85, 2023.

Mild-temperature photothermal treatment method and system based on photoacoustic temperature measurement and control

Yiming Ma, Yang Liu, Zezheng Qin, Yi Shen and Mingjian Sun, “Mild-temperature photothermal treatment method and system based on photoacoustic temperature measurement and control”, Biomedical Signal Processing and Control, Vol. 79, Part 1, 2023.

Effects of acute resistance exercise on myocardial perfusion and left ventricular energy waste: Comparisons between habitually resistance-trained only and combined exercise-trained populations

Chang-Lun Shu, Shiou-Shu Huang, Lian-Yu Lin, and Hsin-Fu Lin, “Effects of acute resistance exercise on myocardial perfusion and left ventricular energy waste: Comparisons between habitually resistance-trained only and combined exercise-trained populations”, Physical Education Journal, 56(3), p.285, 2023.

Visual Perception-Guided Robotic Arm Automatic Ultrasound Scanning 3D Imaging System

Boheng Zhang, Kui Xu, Yunshu Xue, Yi Shen and Mingjian Sun, “Visual Perception-Guided Robotic Arm Automatic Ultrasound Scanning 3D Imaging System”, Ultrasonics, 2023.

Oxygen-loaded microbubble-mediated sonoperfusion and oxygenation for neuroprotection after ischemic stroke reperfusion

Yi-Ju Ho, Hsiang-Lung Cheng, Lun-De Liao, Yu-Chun Lin, Hong-Chieh Tsai and Chih-Kuang Yeh, “Oxygen-loaded microbubble-mediated sonoperfusion and oxygenation for neuroprotection after ischemic stroke reperfusion”, Biomaterials Research, 27, Article number: 65, 2023.

Convolutional sparse coding for compressed sensing photoacoustic CT reconstruction with partially known support

Zezheng Qin, Yiming Ma, Lingyu Ma, Guangxing Liu and Mingjian Sun, “Convolutional sparse coding for compressed sensing photoacoustic CT reconstruction with partially known support”, Biomedical Optics Express, 15(2), p.524-539, 2024.

Ultrafast Doppler Imaging for Early Detection of Synovitis in Rheumatoid Arthritis

Kuo-Lung Lai, Min-Chieh Tsai and Pai-Chi Li, “Ultrafast Doppler Imaging for Early Detection of Synovitis in Rheumatoid Arthritis”, Ultrasound in Medicine & Biology, 2024.

Ultrasound monitoring of simultaneous High-Intensity focused ultrasound (HIFU) therapy using Minimum-Peak-Sidelobe coded excitation

Che-Chou Shen and Nien-Hung Wu, “Ultrasound monitoring of simultaneous High-Intensity focused ultrasound (HIFU) therapy using Minimum-Peak-Sidelobe coded excitation”, Ultrasonics, Vol. 138, 2024.

Fourier-Based Fast 3-D Ultrasound Imaging Using Row–Column-Addressed 2-D Arrays

Shang-Ching Lin and Pai-Chi Li, “Fourier-Based Fast 3-D Ultrasound Imaging Using Row–Column-Addressed 2-D Arrays”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 71(1), p.85-101, 2024.

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Clinical photoacoustic imaging of cancer

Keerthi S. Valluru and Juergen K. Willmann, “Clinical photoacoustic imaging of cancer.”, Ultrasonography, 35(4), P.267-280, 2016.

Ultrasound Echogenicity as an Indicator of Muscle Fatigueduring Functional Electrical Stimulation

Qiang Zhang, Ashwin Iyer, Krysten Lambeth, Kang Kim and Nitin Sharma, “Ultrasound Echogenicity as an Indicator of Muscle Fatigueduring Functional Electrical Stimulation”, Sensors, 22(1):335, 2022.

Hybrid-array-based optoacoustic and ultrasound (OPUS) imaging of biological tissues

X. L. Deán-Ben, E. Merčep, and D. Razansky, “Hybrid-array-based optoacoustic and ultrasound (OPUS) imaging of biological tissues.”, Applied Physics Letters, 110(20) ; published online 19 May 2017.

Multispectral optoacoustic tomography of the human breast: characterisation of healthy tissue and malignant lesions using a hybrid ultrasound-optoacoustic approach

Anne Becker, Max Masthoff, Jing Claussen, Steven James Ford, Wolfgang Roll, Matthias Burg, Peter J. Barth, Walter Heindel, Michael Schäfers, Michel Eisenblätter, Moritz Wildgruber, “Multispectral optoacoustic tomography of the human breast: characterisation of healthy tissue and malignant lesions using a hybrid ultrasound-optoacoustic approach.”, European Society of Radiology, 28(2), P.602-609, 2017.

Multispectral Optoacoustic Tomography for Assessment of Crohn’s Disease Activity

Knieling F., Neufert C., Hartmann A., Claussen J., Urich A., Egger C., Vetter M., Fischer S., Pfeifer L., Hagel A., Kielisch C., Görtz R.S., Wildner D., Engel M., Röther J., Uter W., Siebler J., Atreya R., Rascher W., Strobel D., Neurath M.F., Waldner M.J., “Multispectral Optoacoustic Tomography for Assessment of Crohn’s Disease Activity.”, The New England Journal of medicine, 376(13), P.1292-1294, 2017.

Multispectral Optoacoustic Tomography in Assessment of Breast Tumor Margins During Breast-Conserving Surgery: A First-in-human Case Study

Yonggeng Goh, Ghayathri Balasundaram, Mohesh Moothanchery, Amalina Attia, Xiuting Li, Hann Qian Lim, Neal Burton, Yi Qiu, Thomas Choudary Putti, Ching Wan Chan, Philip Iau, Siau Wei Tang, Celene Wei Qi Ng, Felicity Jane Pool, Premilla Pillay, Wynne Chua, Eide Sterling, Swee Tian Quek, Malini Olivo, “Multispectral Optoacoustic Tomography in Assessment of Breast Tumor Margins During Breast-Conserving Surgery: A First-in-human Case Study.”, Clinical Breast Cancer, 18(6), P.e1247-e1250, 2018.

Multimodal Imaging Approach to Monitor Browning of Adipose Tissue In Vivo

Xin Hui Derryn Chan, Ghayathri Balasundaram2, Amalina Binte Ebrahim Attia, Julian L. Goggi, Boominathan Ramasamy, Weiping Han, Malini Olivo, Shigeki Sugii, “Multimodal Imaging Approach to Monitor Browning of Adipose Tissue In Vivo.”, Journal of Lipid Research, 59(6), P.1071-1078.

Small Molecule Optoacoustic Contrast Agents: An Unexplored Avenue for Enhancing In Vivo Imaging

Matt D. Laramie, Mary K. Smith, Fahad Marmarchi, Lacey R. McNally, and Maged Henary, “Small Molecule Optoacoustic Contrast Agents: An Unexplored Avenue for Enhancing In Vivo Imaging.”, Molecules, 23(11), P.2766, 2018.

Imaging of blood flow and oxygen state with a multi-segment optoacoustic ultrasound array

Elena Merčep, Xosé Luís, Deán-Ben, and DanielRazansky, “Imaging of blood flow and oxygen state with a multi-segment optoacoustic ultrasound array.”, Photoacoustics, 10, P.48-53, 2018.

Optoacoustic Imaging Detects Hormone-Related Physiological Changes of Breast Parenchyma

Oshaani Abeyakoon, Stefan Morscher, Nina Dalhaus, Steven J. Ford, Iosif A. Mendichovszky, Roido Manavaki, Matthew Wallis, Penelope Moyle, Ramona Woitek, Andrew Patterson, Turid Torheim, James Joseph, Isabel Quiros Gonzalez, Sarah Bohndiek, Fiona J. Gilbert, “Optoacoustic Imaging Detects Hormone-Related Physiological Changes of Breast Parenchyma.”, Ultraschall in Med, Published online 7 Jun 2018.

Multispectral optoacoustic tomography of systemic sclerosis

Max Masthoff, Anne Helfen1, Jing Claussen, Wolfgang Roll, Angelos Karlas, Heidemarie Becker, Gert Gabriëls, Jan Riess, Walter Heindel, Michael Schäfers, Vasilis Ntziachristos, Michel Eisenblätter, Ulrich Gerth and Moritz Wildgruber, “Multispectral optoacoustic tomography of systemic sclerosis.”, Journal of biophotonics, First published: 04 July 2018.

Use of Multispectral Optoacoustic Tomography to Diagnose Vascular Malformations

Max Masthoff, Anne Helfen, Jing Claussen, Angelos Karlas, Niklas A. Markwardt, Vasilis Ntziachristos, Michel Eisenblätter, and Moritz Wildgruber, “Use of Multispectral Optoacoustic Tomography to Diagnose Vascular Malformations.”, JAMA Dermatology, Published online September 26, 2018.

Visualizing Alzheimer’s Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7

Sung-Jin Park, Chris Jun Hui Ho, Satoshi Arai, Animesh Samanta, Malini Olivo, and Young-Tae Chang, “Visualizing Alzheimer’s Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7”, Scientific Reports, 9, 12052, 2019.

Assessment of Nonradioactive Multispectral Optoacoustic Tomographic Imaging With Conventional Lymphoscintigraphic Imaging for Sentinel Lymph Node Biopsy in Melanoma

Ingo Stoffels, Philipp Jansen, Maximilian Petri, Lukas Goerdt,Titus J. Brinker, Klaus G. Griewank, Thorsten D. Poeppel, Dirk Schadendorf and Joachim Klode, “Assessment of Nonradioactive Multispectral Optoacoustic Tomographic Imaging With Conventional Lymphoscintigraphic Imaging for Sentinel Lymph Node Biopsy in Melanoma”, JAMA Network Open, 638(3), August 14, 2019.

Transmission–reflection optoacoustic ultrasound (TROPUS) computed tomography of small animals

Elena Merčep, Joaquín L. Herraiz, Xosé Luís Deán-Ben and Daniel Razansky, “Transmission–reflection optoacoustic ultrasound (TROPUS) computed tomography of small animals”, Nature Light: Science & Applicationsvolume, 8, Article number: 18, 2019.

Multispectral optoacoustic tomography of benign and malignant thyroid disorders-a pilot study

Wolfgang Roll, Niklas A. Markwardt, Max Masthoff, Anne Helfen, Jing Claussen, Michel Eisenblätter, Alexa Hasenbach, Sven Hermann, Angelos Karlas, Moritz Wildgruber, Vasilis Ntziachristos and Michael Schäfers, “Multispectral optoacoustic tomography of benign and malignant thyroid disorders-a pilot study”, Journal of Nuclear Medicine, published on March 8, 2019.

Multispectral Optoacoustic Tomography: Intra- and Interobserver Variability Using a Clinical Hybrid Approach

Anne Helfen, Max Masthoff, Jing Claussen, Mirjam Gerwing, Walter Heindel , Vasilis Ntziachristos, Michel Eisenblätter, Michael Köhler and Moritz Wildgruber, “Multispectral Optoacoustic Tomography: Intra- and Interobserver Variability Using a Clinical Hybrid Approach”, Journal of Clinical Medicine. 8(1), 63, 2019.

Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy

Adrian P. Regensburger, Lina M. Fonteyne, Jörg Jüngert, Alexandra L. Wagner, Teresa Gerhalter, Armin M. Nagel, Rafael Heiss, Florian Flenkenthaler, Matthias Qurashi, Markus F. Neurath, Nikolai Klymiuk, Elisabeth Kemter, Thomas Fröhlich, Michael Uder, Joachim Woelfle, Wolfgang Rascher, Regina Trollmann, Eckhard Wolf, Maximilian J. Waldner and Ferdinand Knieling, “Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy”, Nature Medicine, 25, P.1905-1915, 2019.

Visualizing Alzheimer’s Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7

Sung-Jin Park, Chris Jun Hui Ho, Satoshi Arai, Animesh Samanta, Malini Olivo and Young-Tae Chang, “Visualizing Alzheimer’s Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7”, Scientific Reports, 9, Article number: 12052, 2019.

Functionalised iron oxide nanoparticles for multimodal optoacoustic and magnetic resonance imaging

Gavin Bell, Ghayathri Balasundaram, Amalina Binte Ebrahim Attia, Francesca Mandino, Malini Olivo and Ivan P. Parkin, “Functionalised iron oxide nanoparticles for multimodal optoacoustic and magnetic resonance imaging”, Journal of Materials Chemistry B, 13, 2019.

Photoacoustic effect of azo derivatives modified by click reagents and parceled by liposomes

Libin Yang, Liaoliao Li, Hong Gao, Dong Wang, Zhou Yang, Hui Cao and Wanli He, “Photoacoustic effect of azo derivatives modified by click reagents and parceled by liposomes”, Dyes and Pigments, 172, 2020.

Ultrasound Guided Optoacoustic Tomography in Assessment of Tumor Margins for Lumpectomies

Yonggeng Goh, Ghayathri Balasundaram, Mohesh Moothanchery, Amalina Attia, Xiuting Li, Hann Qian Lim, Neal C. Burton, Yi Qiu, Thomas Choudary Putti, Ching Wan Chan, Philip Iau, Shaik Ahmad Buhari, Mikael Hartman, Siau Wei Tang, Celene Wei Qi Ng, Yiong Huak Chan, Felicity Jane Pool, Premilla Pillay, Wynne Chua, Jeevesh Kapur, Pooja Jagmohan, Eide Sterling, Swee Tian Quek and Malini Olivo, “Ultrasound Guided Optoacoustic Tomography in Assessment of Tumor Margins for Lumpectomies”, Translational Oncology, 13(2), P.254-261, 2020.

Ultrasound Guided Optoacoustic Tomography in Assessment of Tumor Margins for Lumpectomies

Yonggeng Goh, Ghayathri Balasundaram, Mohesh Moothanchery, Amalina Attia, Xiuting Li, Hann Qian Lim, Neal C. Burton, Yi Qiu, Thomas Choudary Putti, Ching Wan Chan, Philip Iau, Shaik Ahmad Buhari, Mikael Hartman, Siau Wei Tang, Celene Wei Qi Ng, Yiong Huak Chan, Felicity Jane Pool, Premilla Pillay, Wynne Chua, Jeevesh Kapur, Pooja Jagmohan, Eide Sterling, Swee Tian Quek and Malini Olivo, “Ultrasound Guided Optoacoustic Tomography in Assessment of Tumor Margins for Lumpectomies”, Translational Oncology, 13(2), P.254-261, 2020.

Deep Learning for Automatic Segmentation of Hybrid Optoacoustic Ultrasound (OPUS) Images

Berkan Lafci, Elena Merčep, Stefan Morscher, Xosé Luís Deán-Ben and Daniel Razansky, “Deep Learning for Automatic Segmentation of Hybrid Optoacoustic Ultrasound (OPUS) Images”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 07 September 2020.

Optoacoustic characterization of breast conserving surgery specimens–A pilot study

Ghayathri Balasundaram, Yonggeng Goh, Mohesh Moothanchery, Amalina Attia, Hann Qian Lim, Neal C. Burton, Yi Qiu, Thomas Choudary Putti, Ching Wan Chan, Mikael Hartmann, Swee Tian Quek and Malini Olivo, “Optoacoustic characterization of breast conserving surgery specimens–A pilot study”, Photoacoustics, 19, 2020.

Bedside 3D Visualization of Lymphatic Vessels with a Handheld Multispectral Optoacoustic Tomography Device

Guido Giacalone, Takumi Yamamoto, Florence Belva, and Akitatsu Hayashi, “Bedside 3D Visualization of Lymphatic Vessels with a Handheld Multispectral Optoacoustic Tomography Device”, Jounal of Clinical Medicine, 9(3),815, 2020.

Efficient segmentation of multi-modal optoacoustic and ultrasound images using convolutional neural networks

Berkan Lafci, Elena Merćep, Stefan Morscher, Xosé Luís Deán-Ben, and Daniel Razansky, “Efficient segmentation of multi-modal optoacoustic and ultrasound images using convolutional neural networks”, SPIE BiOS, San Francisco, California, United States, 2020.

Real-time interleaved spectroscopic photoacoustic and ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction

Geng-Shi Jeng, Meng-Lin Li, MinWoo Kim, Soon Joon Yoon, John J. Pitre Jr David S. Li, Ivan Pelivanov and Matthew O’Donnell, “Real-time interleaved spectroscopic photoacoustic and ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction”, Nature Communications, 12:716, 2021.

Multispectral optoacoustic tomography of peripheral arterial disease based on muscle hemoglobin gradients—a pilot clinical study

Angelos Karlas, Max Masthoff, Michael Kallmayer, Anne Helfen, Michail Bariotakis, Nikolina Alexia Fasoula, Michael Schäfers, Max Seidensticker, Hans-Henning Eckstein, Vasilis Ntziachristos and Moritz Wildgruber, “Multispectral optoacoustic tomography of peripheral arterial disease based on muscle hemoglobin gradients—a pilot clinical study”, Annals of Translational Medicine, 9(1): 36, 2021.

Multicompartmental non-invasive sensing of postprandial lipemia in humans with multispectral optoacoustic tomography

Nikolina-Alexia Fasoula, Angelos Karlas, Michael Kallmayer, Anamaria Beatrice Milik, Jaroslav Pelisek, Hans-Henning Eckstein, Martin Klingenspor, and Vasilis Ntziachristos, “Multicompartmental non-invasive sensing of postprandial lipemia in humans with multispectral optoacoustic tomography”, Molecular Metabolism, 47: 101184, 2021.

Multispectral optoacoustic tomography of lipid and hemoglobin contrast in human carotid atherosclerosis

AngelosKarlas, MichaelKallmayer, MichaelBariotakis, Nikolina-AlexiaFasoula, EvangelosLiapis, Fabien Hyafil, Jaroslav Pelisek, Moritz Wildgruber, Hans-Henning Eckstein, and Vasilis Ntziachristos, “Multispectral optoacoustic tomography of lipid and hemoglobin contrast in human carotid atherosclerosis”, Photoacoustics, 23: 100283, 2021.

Clinically translatable quantitative molecular photoacoustic imaging with liposome-encapsulated ICG J-aggregates

Cayla A. Wood, Sangheon Han, Chang Soo Kim, Yunfei Wen, Diego R. T. Sampaio, Justin T. Harris, Kimberly A. Homan, Jody L. Swain, Stanislav Y. Emelianov, Anil K. Sood, Jason R. Cook, Konstantin V. Sokolov, and Richard R. Bouchard, “Clinically translatable quantitative molecular photoacoustic imaging with liposome-encapsulated ICG J-aggregates”, Nature Communications, 12: 5410, 2021.

Image processing improvements afford second-generation handheld optoacoustic imaging of breast cancer patients

Jan Kukačka, Stephan Metz, Christoph Dehner, Alexander Muckenhuber, Korbinian Paul-Yuan, Angelos Karlas, Eva Maria Fallenberg, Ernst Rummeny, Dominik Jüstel and Vasilis Ntziachristos, “Image processing improvements afford second-generation handheld optoacoustic imaging of breast cancer patients”, Photoacoustics, 26, 2022.

DeepMB: Deep neural network for real-time optoacoustic image reconstruction with adjustable speed of sound

Christoph Dehner, Guillaume Zahnd, Vasilis Ntziachristos and Dominik Jüstel, “DeepMB: Deep neural network for real-time optoacoustic image reconstruction with adjustable speed of sound”, arXiv: Image and Video Processing, 27th Sep. 2022.

Multispectral optoacoustic tomography for in vivo detection of lymph node metastases in oral cancer patients using an EGFR-targeted contrast agent and intrinsic tissue contrast: A proof-of-concept study

J. Vonk, J. Kukačka, P.J. Steinkamp, J.G. de Wit, F.J. Voskuil, W.T.R. Hooghiemstra, M. Bader, D. Jüstel, V. Ntziachristos, G.M. van Dam and M.J.H. Witjes, “Multispectral optoacoustic tomography for in vivo detection of lymph node metastases in oral cancer patients using an EGFR-targeted contrast agent and intrinsic tissue contrast: A proof-of-concept study”, Photoacoustics, 26, 2022.

An optoacoustic imaging feature set to characterise blood vessels surrounding benign and malignant breast lesions

O. Abeyakoon, R. Woitek, M.G. Wallis, P.L. Moyle, S. Morscher, N. Dahlhaus, S.J. Ford, N.C. Burton, R. Manavaki, I.A. Mendichovszky, J. Joseph, I. Quiros-Gonzalez, S.E. Bohndiek F.J. Gilbert, “An optoacoustic imaging feature set to characterise blood vessels surrounding benign and malignant breast lesions”, Photoacoustics, 27, 2022.

Biochemical “decoding” of breast ultrasound images with optoacoustic tomography fusion: First-in-human display of lipid and collagen signals on breast ultrasound

Yonggeng Goh, Ghayathri Balasundaram, Hui Min Tan, Thomas Choudary Putti, Siau Wei Tang, Celene Wei Qi Ng, Shaik Ahmad Buhari, Eric Fang, Mohesh Moothanchery, Renzhe Bi, Malini Olivo and Swee Tian Quek, “Biochemical “decoding” of breast ultrasound images with optoacoustic tomography fusion: First-in-human display of lipid and collagen signals on breast ultrasound”, Photoacoustics, 27, 2022.

Photoacoustic Tomography Appearance of Fat Necrosis: A First-in-Human Demonstration of Biochemical Signatures along with Histological Correlation

Yonggeng Goh, Ghayathri Balasundaram, Hui Min Tan, Thomas Choudary Putti, Celene Wei Qi Ng, Eric Fang, Renzhe Bi, Siau Wei Tang, Shaik Ahmad Buhari, Mikael Hartman, Ching Wan Chan, Yi Ting Lim, Malini Olivo, and Swee Tian Quek, “Photoacoustic Tomography Appearance of Fat Necrosis: A First-in-Human Demonstration of Biochemical Signatures along with Histological Correlation”, Diagnostics, 12(10):2456, 2022.

Multispectral optoacoustic tomography for the non-invasive identification of patients with severe anemia in vivo

Ingo Ganzleben, Daniel Klett, Wiebke Hartz, Lisa Götzfried, Francesco Vitali, Markus F. Neurath and Maximilian J. Waldner, “Multispectral optoacoustic tomography for the non-invasive identification of patients with severe anemia in vivo”, Photoacoustics, 28, 2022.

Multispectral optoacoustic tomography for non-invasive disease phenotyping in pediatric spinal muscular atrophy patients

Adrian P. Regensburger, Alexandra L. Wagner, Vera Danko, Jörg Jüngert, Anna Federle, Daniel Klett, Stephanie Schuessler, Adrian Buehler, Markus F. Neurath, Andreas Roos, Hanns Lochmüller, Joachim Woelfle, Regina Trollmann, Maximilian J. Waldner and Ferdinand Knieling, “Multispectral optoacoustic tomography for non-invasive disease phenotyping in pediatric spinal muscular atrophy patients”, Photoacoustics, 25, 2022.

Spotlight on Nerves: Portable Multispectral Optoacoustic Imaging of Peripheral Nerve Vascularization and Morphology

Dominik Jüstel, Hedwig Irl, Florian Hinterwimmer, Christoph Dehner, Walter Simson, Nassir Navab, Gerhard Schneider and Vasilis Ntziachristos, “Spotlight on Nerves: Portable Multispectral Optoacoustic Imaging of Peripheral Nerve Vascularization and Morphology”, Advanced Science, 10(19), 2023.

Towards in vivo characterization of thyroid nodules suspicious for malignancy using multispectral optoacoustic tomography

Milou E. Noltes, Maximilian Bader, Madelon J. H. Metman, Jasper Vonk, Pieter J. Steinkamp, Jan Kukačka, Henriette E. Westerlaan, Rudi A. J. O. Dierckx, Bettien M. van Hemel, Adrienne H. Brouwers, Gooitzen M. van Dam, Dominik Jüstel, Vasilis Ntziachristos and Schelto Kruijff, “Towards in vivo characterization of thyroid nodules suspicious for malignancy using multispectral optoacoustic tomography”, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 50, p.2736-2750, 2023.

Targeting Muscular Hemoglobin Content for Classification of Peripheral Arterial Disease by Noninvasive Multispectral Optoacoustic Tomography

Josefine S. Günther, Ferdinand Knieling, Anna P. Träger, Werner Lang, Alexander Meyer, Adrian P. Regensburger, Alexandra L. Wagner, Regina Trollmann, Joachim Woelfle, Daniel Klett, Wolfgang Uter, Michael Uder, Markus F. Neurath, Maximilian J. Waldner, and Ulrich Rother, “Targeting Muscular Hemoglobin Content for Classification of Peripheral Arterial Disease by Noninvasive Multispectral Optoacoustic Tomography”, Journals of the American College of Cardiology: Cardiovascular Imaging, 16(5), p.719-721, 2023.

A deep neural network for real-time optoacoustic image reconstruction with adjustable speed of sound

Christoph Dehner, Guillaume Zahnd, Vasilis Ntziachristos, and Dominik Jüstel, “A deep neural network for real-time optoacoustic image reconstruction with adjustable speed of sound”, Nature Machine Intelligence, 5, p.1130-1141, 2023.

Contrast-Enhanced Multispectral Optoacoustic Tomography for Functional Assessment of the Gastrointestinal Tract

Lars-Philip Paulus, Adrian Buehler, Alexandra L. Wagner, Roman Raming, Jörg Jüngert, David Simon, Koray Tascilar, Alexander Schnell, Ulrich Rother, Markus Eckstein, Werner Lang, André Hoerning, Georg Schett, Markus F. Neurath, Maximilian J. Waldner, Regina Trollmann, Joachim Woelfle, Sarah E Bohndiek, Adrian P. Regensburger and Ferdinand Knieling, “Contrast-Enhanced Multispectral Optoacoustic Tomography for Functional Assessment of the Gastrointestinal Tract”, Advanced Science, 2023.

Hybrid reflected-ultrasound computed tomography versus B-mode-ultrasound for muscle scoring in spinal muscular atrophy

Vera Danko, Jörg Jüngert, Stephanie Schuessler, Adrian Buehler, Daniel Klett, Anna Federle, Andreas Roos, Hanns Lochmüller, Markus F. Neurath, Joachim Woelfle, Regina Trollmann, Maximilian J. Waldner, Ferdinand Knieling, Adrian P. Regensburger and Alexandra L. Wagner, “Hybrid reflected-ultrasound computed tomography versus B-mode-ultrasound for muscle scoring in spinal muscular atrophy”, Journal of Neuroimaging, 33(3), p.393-403, 2023.

Multispectral optoacoustic tomography of the human intestine – temporal precision and the influence of postprandial gastrointestinal blood flow

Lars-Philip Paulus, Alexandra L. Wagner, Adrian Buehler, Roman Raming, Jörg Jüngert, David Simon, Koray Tascilar, Alexander Schnell, Josefine Günther, Ulrich Rother, Werner Lang, André Hoerning, Georg Schett, Markus F. Neurath, Joachim Woelfle, Maximilian J. Waldner, Ferdinand Knieling, and Adrian P. Regensburger, “Multispectral optoacoustic tomography of the human intestine – temporal precision and the influence of postprandial gastrointestinal blood flow”, Photoacoustics, Vol. 30, 2023.

Derivation and validation of a non-invasive optoacoustic imaging biomarker for patients with intermittent claudication

Milenko Caranovic, Julius Kempf, Yi Li, Adrian P. Regensburger, Josefine S. Günther, Anna P. Träger, Werner Lang, Alexander Meyer, Alexandra L. Wagner, Joachim Woelfle, Roman Raming, Lars-Philip Paulus, Adrian Buehler, Wolfgang Uter, Michael Uder, Christian-Alexander Behrendt, Markus F. Neurath, Maximilian J. Waldner, Ferdinand Knieling and Ulrich Rother, “Derivation and validation of a non-invasive optoacoustic imaging biomarker for patients with intermittent claudication”, medRxiv, 2023.

Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography

Koray Tascilar, Filippo Fagni, Arnd Kleyer, Sara Bayat, Robert Heidemann, Florian Steiger, Gerhard Krönke, Daniela Bohr, Andreas Ramming, Fabian Hartmann, Daniel Klett, Anna Federle, Adrian P Regensburger, Alexandra L Wagner, Ferdinand Knieling, Markus F Neurath, Georg Schett, Maximilian Waldner and David Simon, “Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography”, Rheumatology, 62(2), p.841-849, 2023.

Optoacoustic Endoscopy of the Gastrointestinal Tract

Hailong He, Ludwig Englert, and Vasilis Ntziachristos, “Optoacoustic Endoscopy of the Gastrointestinal Tract”, ACS Photonics, 10, 3, p.559-570, 2023.

Multispectral optoacoustic tomography enables assessment of disease activity in paediatric inflammatory bowel disease

Adrian P. Regensburger, Markus Eckstein, Matthias Wetzl, Roman Raming, Lars-Philip Paulus, Adrian Buehler, Emmanuel Nedoschill, Vera Danko, Jörg Jüngert, Alexandra L. Wagner, Alexander Schnell, Aline Rückel, Ulrich Rother, Oliver Rompel, Michael Uder, Arndt Hartmann, Markus F. Neurath, Joachim Woelfle, Maximilian J. Waldner, André Hoerning and Ferdinand Knieling, “Multispectral optoacoustic tomography enables assessment of disease activity in paediatric inflammatory bowel disease”, Photoacoustics, Vol. 35, 2024.